(1) While estradiol levels were equivalent in these two groups, the rise in LH after ovariectomy was prevented by the immediate administration in the pseudo-intact rats, while the augmented plasma LH levels present three weeks following ovariectomy were only reduced by 50% as a result of delayed estradiol treatment.
(2) Decreased levels of receptors for estradiol-17beta, progesterone, and prolactin were found in the tumors remaining after ovariectomy while treatment with the dose (24 mug) of RU 16117, efficient to inhibit tumor growth, has a similar inhibitory effect on the levels of estradiol-17beta and prolactin receptors.
(3) Neonatal ovariectomy raised 3H-estradiol concentrations in all tissues, except hippocampus and anterior pituitary, suggesting an increase in nonspecifically bound hormone.
(4) The osteopenic effects of prednisolone and ovariectomy were additive and independent.
(5) Estrous cycles were not disrupted by removal of the autogenous ovaries 8 wk after the grafting, indicating that grafted ovaries began functioning before or within days after ovariectomy.
(6) Both experiments were conducted using an animal model in which pulsatile secretion of gonadotropin-releasing hormone (GnRH) and endogenous secretion of ovarian steroids were eliminated by ovariectomy during seasonal anestrus and treatment with Silastic implants which maintained a luteal-phase level of serum progesterone.
(7) While the production of material rich in cysteine increases after ovariectomy (Dürnberger et al., 1978), the fine structure of the cells is essentially unchanged.
(8) In submandibular glands, 1 to 4 weeks after ovariectomy, no changes were observed in percentages of the acinar, intercalated duct, and granular convoluted tubular areas occupying photomicrographs.
(9) The results demonstrated that both oestradiol and tamoxifen induced a temporary growth delay, whereas ovariectomy of the host had no effect on the growth of the tumour.
(10) A similar effect was detected in them after combined adrenal- and ovariectomy.
(11) After ovariectomy, LH-beta mRNA levels increased 2- to 2.5-fold, while alpha mRNA levels increased 2.5-fold 6 and 10 days after ovariectomy.
(12) Within 6 h of ovariectomy in adult rats with 4-day estrous cycles, plasma FSH titers were significantly elevated above those of sham-operated controls at all stages of the estrous cycle, whereas plasma LH concentrations were raised by ovariectomy only during diestrus day 2, proestrus or estrus.
(13) Following unilateral ovariectomy in the rat, the remaining ovary undergoes rapid compensatory changes including an increase in the number of antral follicles (follicular activation) and an increase in ovarian weight (compensatory ovarian hypertrophy).
(14) However, ovariectomy induces female beta-cell degeneration similar to that in the males.
(15) Morphological alterations in the shape of germinal centres was noted after ovariectomy in adult and immature mice.
(16) In spite of the weak feedback response of the neonatal rats to ovariectomy, diethylstilbestrol suppressed the basal pituitary gonadotropin concentrations and the specific LH and FSH beta-chain mRNAs (p < 0.01-0.05).
(17) In uterus, ER mRNA increased 3- to 6-fold after ovariectomy, and returned to intact levels within 24 h of E2 replacement.
(18) Ovariectomy, on the other hand, depressed, whereas chronic administration of estradiol 17-beta enhanced the pressor response to the thromboxane mimic, but had no effect on the response to angiotensin II.
(19) A total of 35 menstruating women undergoing ovariectomy were randomly divided into five groups of 7 patients each, receiving a 4-week treatment with oral clonidine, lisuride and sodium valproate, transdermal 17 beta-estradiol, or placebo.
(20) Thyroidectomy did not alter the concentration of serum IR-GnRH and IR-TRH in Ovx rats on days 70 and 90 post-ovariectomy.
Ovary
Definition:
(n.) That part of the pistil which contains the seed, and in most flowering plants develops into the fruit. See Illust. of Flower.
(n.) The essential female reproductive organ in which the ova are produced. See Illust. of Discophora.
Example Sentences:
(1) Although Jeggo's Chinese hamster ovary cells were more responsive to mAMSA, novo still abrogated mAMSA toxicity in the mutant cells as well as in the parental Chinese hamster ovary cells 2,4-Dinitrophenol acted similarly to novo with respect to mAMSA killing, but neither compound reduced the ATP content of V79 cells.
(2) This study was designed to investigate the localization and cyclic regulation of the mRNA for these two IGFBPs in the porcine ovary, RNA was extracted from whole ovaries morphologically classified as immature, preovulatory, and luteal.
(3) Stimulation of dopamine D2 receptors potentiates Ca2+ ionophore- or ATP-induced arachidonic acid (AA) release in D2 receptor cDNA-transfected Chinese hamster ovary (CHO) cells [CHO(D2)].
(4) Stable mutants which are between 1.6- and 2.2-fold resistant to the microtubule inhibitor, nocodazole (NocR mutants) have been isolated in Chinese hamster ovary cells after a single-step selection.
(5) Ovarian venous concentrations of these four steroids from the side draining the tumor-bearing ovary were increased in 40 to 80% of the women.
(6) Ovarian aromatase activity, assessed by incubating the homogenised ovaries of treated rats with tritium-labelled androstenedione (0.2 microM) or testosterone (1 microM), indicated that residual enzyme activity was reduced compared with controls.
(7) The normal tissues included the ovary, fallopian tube, uterine endometrium, uterine cervix, and vagina.
(8) To determine where in the cell cycle Chinese hamster ovary cells die following heating in G1, a mild hyperthermia treatment, i.e., 10 or 11.5 min at 45.5 degrees C, resulting in 40-50% cell kill was used.
(9) The clinical and pathological features of a patient with giant cell arteritis of the uterus and ovaries are described.
(10) The surface of the ovary has been found to be composed of two types of epithelial cells called A and B cells which are found in their own respective zones, the A and B zones.
(11) As early as postnatal Day 2, NPY-I nerves were observed in connective tissue septa of the developing ovary.
(12) This increase was consistent with the stimulation of the total renin concentration in the ovary.
(13) Only 7 of 241 hatchlings had gonads that had not differentiated fully into ovaries or testes.
(14) We now report on the Singapore Chinese experience, in which the following changes were notable: decreases in rates of cancers of the stomach and oesophagus and increases in rates of cancers of the lung, colon, rectum, skin (excluding melanoma), breast and ovary.
(15) This study demonstrated that the ovaries did not influence uterine growth until after 60 d of age and that unilateral ovariohysterectomy could be performed as early as 60 d of age without altering consequent normal uterine growth.
(16) In ovaries, GtH stimulates production of 17 alpha-hydroxyprogesterone in the thecal cells.
(17) We have used a rapid in vivo recombinational method to clone and completely sequence 34 UV-induced mutants at the adenine phosphoribosyltransferase (APRT) locus of Chinese hamster ovary cells.
(18) None of the rete-depleted ovaries exhibited normal follicular differentiation regardless of the presence or absence of the surface epithelium, whereas follicles developed normally in all the implants containing the rete system.
(19) Interpretation of the results shows that the ovary of the European eel contains the following enzymes: a 3 beta-hydroxysteroid dehydrogenase, 5----4-ene-isomerase complex, a 17 alpha-hydroxylase, a C21-C19 desmolase, a 17 beta-hydroxysteroid oxidoreductase, a 5 alpha-reductase, a 3 beta-hydroxysteroid oxidoreductase and an aromatase complex.
(20) The data are expressed as percent inhibition of ovulation in the treated vs. the untreated ovaries.