(v. t.) To get the better of; to surmount; to conquer; to subdue; as, to overcome enemies in battle.
(v. t.) To overflow; to surcharge.
(v. t.) To come or pass over; to spreads over.
(v. i.) To gain the superiority; to be victorious.
Example Sentences:
(1) To overcome this difficulty, a "hetero-antibody" RIA was studied.
(2) To overcome these problems we developed methotrexate bone cement (MTX-Palacos) with the aim to obtain high local concentrations of methotrexate in order to destroy remaining tumor cells and avoid systemic side effects.
(3) This phenomenon may be overcome by utilizing more dextran-coated charcoal in the extraction.
(4) The diet dilution technique overcomes the major disadvantage of the graded supplementation method for determining the requirements of amino acids, namely that of the amino acid balance changing systematically in successive dietary treatments.
(5) This was overcome by using a continuous subcutaneous infusion pump which also enabled the effective daily dosage to be reduced and thereby adverse reactions to be avoided.
(6) If this is the only issue, flight would be fine, but need to make sure that it isn’t symptomatic of a more significant upstream root cause.” Elon Musk (@elonmusk) Btw, 99% likely to be fine (closed loop TVC wd overcome error), but that 1% chance isn't worth rolling the dice.
(7) The model is meant to overcome the diffusional limitations, caused by a microcapsulated membrane.
(8) To overcome the problem of incontinence which failed to respond to standard measures, an animal model was designed for continent diversion without cystectomy.
(9) Results indicate that the rachitogenic factor in rye is not present in the ash portion of the grain, that it can be largely overcome by water extraction and penicillin supplementation, and that an organic solvent extraction has no effect.
(10) We interpret this exaggerated positive attitude as an attempt to overcome inner fears, doubts and ambivalences.
(11) In contrast, addition of CsA-plus-exogenous-IL-2 within the first 4 hr of culture did not overcome the immunosuppressive effect of CsA.
(12) Intraruminal sustained release devices largely overcome this problem and constitute the most important new technology.
(13) Many of the limitations of conventional diagnostic arthroscopy of the knee have been largely overcome through the development of techniques that permit manipulation of intra-articular structures through paired, coordinated entry sites.
(14) In an attempt to overcome some of these difficulties, the concept of excess mortality was suggested, which is independent of death cause diagnoses or coding routines, as well as of the rate of detection of non-fatal cancer.
(15) To overcome some of these problems it is suggested that an investigation of lay evaluation of health care should be carried out within a conceptual framework which incorporates the following elements.
(16) Introduction of D 600 of the perfusion medium reduced release of catecholamines in response to acetylcholine, and this reduction was overcome by raising calcium ion concentrations of the perfusion medium.
(17) To help overcome this problem, a stereoscopic slide-based auto-instructional program has been developed as a substitute for dissection.
(18) Unlike cycloheximide (CXM) which inhibits long-term memory by inhibiting ribosomal protein synthesis, AIB is non-effective when administered 10 min or more after learning, and its effect is overcome by the sodium pump stimulator diphenylhydantoin if the latter is administered 10 min or more after learning.
(19) Plasma membranes from activated T cells stimulated HIV production, suggesting cell contact induces factor(s) in monocytes to overcome latency.
(20) The results demonstrate the usefulness of polyacrylamide-gel electrophoresis to detect and overcome aggregation problems with membrane proteins and suggest that detergent mixtures in specific ratios may be useful in the purification of adenylate cyclase and other intrinsic membrane proteins.
Profligate
Definition:
(a.) Overthrown; beaten; conquered.
(a.) Broken down in respect of rectitude, principle, virtue, or decency; openly and shamelessly immoral or vicious; dissolute; as, profligate man or wretch.
(n.) An abandoned person; one openly and shamelessly vicious; a dissolute person.
(v. t.) To drive away; to overcome.
Example Sentences:
(1) But this is not to say that I do not have a working knowledge of true bedsitters - and yes, they do still exist, in spite of estate agents' profligate use of the term 'studio flat'.
(2) But it relies too much on the myth that booms enrich everyone, a myth easily exposed by pointing out that under that supposedly profligate Labour administration, now accused of recklessly taking from the rich and giving to the poor, the gap between the richest and the poorest didn't narrow.
(3) "With a 53 per cent increase in energy consumption forecast by 2035, those who are commercially savvy will recognise that in a resource poor future, we cannot be captured by a profligate economic model from the past.
(4) Reasonable use” sounds … well, reasonable, but a “use it or lose it” clause incentivizes profligate use: if you don’t use your historic water allocation in a beneficial way, you forfeit your water rights, Gray said.
(5) The coalition succeeded an unbelievably profligate government that took state spending from 34% of GDP to over 45% in a decade .
(6) Other critics say low water prices are the culprits as they result in profligate water use and low investment in water-efficient infrastructure.
(7) All the debt ceiling ends up becoming is a political football used by the opposition party to suggest the government are profligate spenders.
(8) He believes that Osborne's decision to veto the measures in February shows that the Tories want to put spending cuts ahead of tackling child poverty as he seeks to depict Labour as profligate.
(9) The credit crunch hit, which might have been terminal to a project so palpably of the profligate boom years, but then the cavalry appeared, in the form of the property arm of the ruling family of Qatar.
(10) Thatcherism liked to present itself as a rejection of the postwar, state-driven, more profligate way of doing things.
(11) There is no reason why a constitutional solution that involves debt limitation should not command a large measure of public acceptance, especially in debtor countries, which have experienced the political and economic damage caused by previous profligate governments.
(12) In Brussels, right-of-centre German economists, who until recently dominated the European Central Bank's main decision-making board, lobbied for a "can't-pay, won't-pay" stance towards southern European countries seen as profligate spenders who need to understand the moral hazard of raising their living standards on a mountain of debt.
(13) The latest shock wave has served to ram home the reality that this remains first of all a crisis of the banks and the private sector – not, as the British government would have it, of profligate governments and public debt, which only ballooned to fill the gap left by market failure.
(14) Election officials have also disqualified Raja Pervaiz Ashraf, the man who until just a few weeks ago was the country's prime minister, under articles ensuring candidates are, among many other things, "sagacious, righteous and non-profligate".
(15) As inspectors from Brussels demanded answers this week from the Spanish government about how it plans to bring profligate regional governments under control, senior officials admitted they were clueless as to the real size of the debt in the biggest region – party-loving Andalucía.
(16) "People have far more confidence in Britain than in many other western countries who have got into trouble through profligate economic policies," he said.
(17) London, which has less annual rainfall than cities such as Athens and Sydney, is classed as "seriously water-stressed" by the Environment Agency , but critics of the Beckton plant – including former mayor of London Ken Livingstone – told the inquiry that desalination was energy-profligate, unnecessary and unsustainable.
(18) More and more people feel the gap between the profligate promises of individual freedom and sovereignty, and the incapacity of their political and economic organisations to realise them.
(19) His party has no members of parliament, a situation unlikely to change at the next election, and offers promiscuous and profligate policies that add up to errant nonsense as a platform for government.
(20) That debacle shows the Conservatives as being as profligate as sailors on shore leave.