(v. t.) To get the better of; to surmount; to conquer; to subdue; as, to overcome enemies in battle.
(v. t.) To overflow; to surcharge.
(v. t.) To come or pass over; to spreads over.
(v. i.) To gain the superiority; to be victorious.
Example Sentences:
(1) To overcome this difficulty, a "hetero-antibody" RIA was studied.
(2) To overcome these problems we developed methotrexate bone cement (MTX-Palacos) with the aim to obtain high local concentrations of methotrexate in order to destroy remaining tumor cells and avoid systemic side effects.
(3) This phenomenon may be overcome by utilizing more dextran-coated charcoal in the extraction.
(4) The diet dilution technique overcomes the major disadvantage of the graded supplementation method for determining the requirements of amino acids, namely that of the amino acid balance changing systematically in successive dietary treatments.
(5) This was overcome by using a continuous subcutaneous infusion pump which also enabled the effective daily dosage to be reduced and thereby adverse reactions to be avoided.
(6) If this is the only issue, flight would be fine, but need to make sure that it isn’t symptomatic of a more significant upstream root cause.” Elon Musk (@elonmusk) Btw, 99% likely to be fine (closed loop TVC wd overcome error), but that 1% chance isn't worth rolling the dice.
(7) The model is meant to overcome the diffusional limitations, caused by a microcapsulated membrane.
(8) To overcome the problem of incontinence which failed to respond to standard measures, an animal model was designed for continent diversion without cystectomy.
(9) Results indicate that the rachitogenic factor in rye is not present in the ash portion of the grain, that it can be largely overcome by water extraction and penicillin supplementation, and that an organic solvent extraction has no effect.
(10) We interpret this exaggerated positive attitude as an attempt to overcome inner fears, doubts and ambivalences.
(11) In contrast, addition of CsA-plus-exogenous-IL-2 within the first 4 hr of culture did not overcome the immunosuppressive effect of CsA.
(12) Intraruminal sustained release devices largely overcome this problem and constitute the most important new technology.
(13) Many of the limitations of conventional diagnostic arthroscopy of the knee have been largely overcome through the development of techniques that permit manipulation of intra-articular structures through paired, coordinated entry sites.
(14) In an attempt to overcome some of these difficulties, the concept of excess mortality was suggested, which is independent of death cause diagnoses or coding routines, as well as of the rate of detection of non-fatal cancer.
(15) To overcome some of these problems it is suggested that an investigation of lay evaluation of health care should be carried out within a conceptual framework which incorporates the following elements.
(16) Introduction of D 600 of the perfusion medium reduced release of catecholamines in response to acetylcholine, and this reduction was overcome by raising calcium ion concentrations of the perfusion medium.
(17) To help overcome this problem, a stereoscopic slide-based auto-instructional program has been developed as a substitute for dissection.
(18) Unlike cycloheximide (CXM) which inhibits long-term memory by inhibiting ribosomal protein synthesis, AIB is non-effective when administered 10 min or more after learning, and its effect is overcome by the sodium pump stimulator diphenylhydantoin if the latter is administered 10 min or more after learning.
(19) Plasma membranes from activated T cells stimulated HIV production, suggesting cell contact induces factor(s) in monocytes to overcome latency.
(20) The results demonstrate the usefulness of polyacrylamide-gel electrophoresis to detect and overcome aggregation problems with membrane proteins and suggest that detergent mixtures in specific ratios may be useful in the purification of adenylate cyclase and other intrinsic membrane proteins.
Surmount
Definition:
(v. i.) To rise above; to be higher than; to overtop.
(v. i.) To conquer; to overcome; as, to surmount difficulties or obstacles.
(v. i.) To surpass; to exceed.
Example Sentences:
(1) This report describes how the difficulties were surmounted, and how the National Technical Centre then proceeded to undertake activities to extend awareness of the ICIDH.
(2) In calf tracheae, ketanserin caused surmountable antagonism of the effects of 5-HT with a pKB of 9.5.
(3) The results indicate that metoclopramide is a potent, surmountable and selective antagonist of tryptamine receptors on rabbit cardiac sympathetic nerves.
(4) The inhibitory effect on degranulation could not be surmounted even by concentrations of PAF 10-fold higher than that of 1-acyl-2-acetyl-GPC.
(5) One line of tumour proved to be sensitive to inhibition by a histamine H2 receptor antagonist and a dopamine D2 antagonist but resistant to serotonin antagonists; the inhibition by histamine antagonists was surmountable by co-administration of histamine.
(6) Our experience indicated that: It is possible to increase and enrich dream activity in quantity and in substance in the course of the treatment; This approach can affect all of the components of the personality which have been in regression after injury; Dream analysis does not require complex cognitive abilities and surmounts the special difficulty these patients have in using language and abstract concepts; It is possible to bring to the surface inner and subconscious contents residing in the patient that were ignored before; and The residual content of the premorbid personality is also expressed, thus facilitating the patient's inner contact between his former identity and his new one.
(7) Barriers to the effective dissemination of HIV prevention education are identified and strategies that may be effective in surmounting these barriers and implementing culturally-appropriate HIV behavioral modification programs are described.
(8) We hope that through our efforts we can surmount these difficulties, improve the quality of medical care in our country, and create a more rational economic and scientific basis for future medical development and advances.
(9) Hence, these tetanic contractions are not due to a surmounting of the atropine-block by the increased release of acetylcholine following the 50 pulses.4.
(10) Be resolute, fear no sacrifice, and surmount every difficulty to win victory!” read one famous counsel.
(11) These data show that behavior-relevant information transmitted by GABAergic drugs surmounted that transmitted by cholinergic drugs which, in turn, surmounted behavior-relevant information transmitted by dopaminergic drugs.
(12) In Model II, this difficulty is surmounted, but the formula is no longer exact.
(13) Some fibers produced very small spikes surmounted on large EPPs.
(14) We reinvestigated if it was possible to reveal this phenomenon by carefully choosing a concentration of the alpha adrenoceptor blocker prazosin that would give a significant displacement while it still was possible to completely surmount the blockade by reasonable concentrations of norepinephrine.
(15) In the absence of U46619, 5-HT responses were mediated predominantly by 5-HT2-receptors as judged by potent, surmountable antagonism by the selective 5-HT2 receptor antagonists, spiperone and ketanserin.
(16) After summarizing the health situation in Honduras and describing the National Health Plan launched in 1973, the authors explain the changes that have come about in nursing, the difficulties that had to be surmounted to reach a new professional position, and the administrative decisions that had to be taken to devise a health policy.
(17) In this paper, SDZ 205-557 (2-methoxy-4-amino-5-chloro-benzoic acid 2-(diethylamino) ethyl ester) is characterized as the first potent, selective and surmountable antagonist at 5-HT4 receptors in the isolated guinea pig ileum.
(18) The LV mechanical disadvantage of shock hearts was not correlated with changes in beating frequency, active state duration, or tissue water content; neither was it surmounted by pyruvate nor by maximally effective increases in coronary flow, diastolic stretch, or extracellular Ca2+ concentration.
(19) Trazodone and spiperone were apparently simple competitive antagonists since they produced antagonism that was surmountable over the concentration range studied and, in each tissue, their apparent affinity appeared to be independent of the antagonist concentration.
(20) There is an energy barrier at the channel entrance; if the ion could surmount this barrier, it would be quite stable within the channel.