(v. t.) To get the better of; to surmount; to conquer; to subdue; as, to overcome enemies in battle.
(v. t.) To overflow; to surcharge.
(v. t.) To come or pass over; to spreads over.
(v. i.) To gain the superiority; to be victorious.
Example Sentences:
(1) To overcome this difficulty, a "hetero-antibody" RIA was studied.
(2) To overcome these problems we developed methotrexate bone cement (MTX-Palacos) with the aim to obtain high local concentrations of methotrexate in order to destroy remaining tumor cells and avoid systemic side effects.
(3) This phenomenon may be overcome by utilizing more dextran-coated charcoal in the extraction.
(4) The diet dilution technique overcomes the major disadvantage of the graded supplementation method for determining the requirements of amino acids, namely that of the amino acid balance changing systematically in successive dietary treatments.
(5) This was overcome by using a continuous subcutaneous infusion pump which also enabled the effective daily dosage to be reduced and thereby adverse reactions to be avoided.
(6) If this is the only issue, flight would be fine, but need to make sure that it isn’t symptomatic of a more significant upstream root cause.” Elon Musk (@elonmusk) Btw, 99% likely to be fine (closed loop TVC wd overcome error), but that 1% chance isn't worth rolling the dice.
(7) The model is meant to overcome the diffusional limitations, caused by a microcapsulated membrane.
(8) To overcome the problem of incontinence which failed to respond to standard measures, an animal model was designed for continent diversion without cystectomy.
(9) Results indicate that the rachitogenic factor in rye is not present in the ash portion of the grain, that it can be largely overcome by water extraction and penicillin supplementation, and that an organic solvent extraction has no effect.
(10) We interpret this exaggerated positive attitude as an attempt to overcome inner fears, doubts and ambivalences.
(11) In contrast, addition of CsA-plus-exogenous-IL-2 within the first 4 hr of culture did not overcome the immunosuppressive effect of CsA.
(12) Intraruminal sustained release devices largely overcome this problem and constitute the most important new technology.
(13) Many of the limitations of conventional diagnostic arthroscopy of the knee have been largely overcome through the development of techniques that permit manipulation of intra-articular structures through paired, coordinated entry sites.
(14) In an attempt to overcome some of these difficulties, the concept of excess mortality was suggested, which is independent of death cause diagnoses or coding routines, as well as of the rate of detection of non-fatal cancer.
(15) To overcome some of these problems it is suggested that an investigation of lay evaluation of health care should be carried out within a conceptual framework which incorporates the following elements.
(16) Introduction of D 600 of the perfusion medium reduced release of catecholamines in response to acetylcholine, and this reduction was overcome by raising calcium ion concentrations of the perfusion medium.
(17) To help overcome this problem, a stereoscopic slide-based auto-instructional program has been developed as a substitute for dissection.
(18) Unlike cycloheximide (CXM) which inhibits long-term memory by inhibiting ribosomal protein synthesis, AIB is non-effective when administered 10 min or more after learning, and its effect is overcome by the sodium pump stimulator diphenylhydantoin if the latter is administered 10 min or more after learning.
(19) Plasma membranes from activated T cells stimulated HIV production, suggesting cell contact induces factor(s) in monocytes to overcome latency.
(20) The results demonstrate the usefulness of polyacrylamide-gel electrophoresis to detect and overcome aggregation problems with membrane proteins and suggest that detergent mixtures in specific ratios may be useful in the purification of adenylate cyclase and other intrinsic membrane proteins.
Wild
Definition:
(superl.) Living in a state of nature; inhabiting natural haunts, as the forest or open field; not familiar with, or not easily approached by, man; not tamed or domesticated; as, a wild boar; a wild ox; a wild cat.
(superl.) Growing or produced without culture; growing or prepared without the aid and care of man; native; not cultivated; brought forth by unassisted nature or by animals not domesticated; as, wild parsnip, wild camomile, wild strawberry, wild honey.
(superl.) Desert; not inhabited or cultivated; as, wild land.
(superl.) Savage; uncivilized; not refined by culture; ferocious; rude; as, wild natives of Africa or America.
(superl.) Not submitted to restraint, training, or regulation; turbulent; tempestuous; violent; ungoverned; licentious; inordinate; disorderly; irregular; fanciful; imaginary; visionary; crazy.
(superl.) Exposed to the wind and sea; unsheltered; as, a wild roadstead.
(superl.) Indicating strong emotion, intense excitement, or /ewilderment; as, a wild look.
(superl.) Hard to steer; -- said of a vessel.
(n.) An uninhabited and uncultivated tract or region; a forest or desert; a wilderness; a waste; as, the wilds of America; the wilds of Africa.
(adv.) Wildly; as, to talk wild.
Example Sentences:
(1) In contrast, resting cells of strain CHA750 produced five times less IAA in a buffer (pH 6.0) containing 1 mM-L-tryptophan than did resting cells of the wild-type, illustrating the major contribution of TSO to IAA synthesis under these conditions.
(2) Comparison of wild type and the mutant parD promoter sequences indicated that three short repeats are likely involved in the negative regulation of this promoter.
(3) Insensitive variants die more slowly than wild type cells, with 10-20% cell death observed within 24 h after addition of dexamethasone.
(4) But when he speaks, the crowds who have come together to make a stand against government corruption and soaring fuel prices cheer wildly.
(5) RNAs encoding a wild-type (RBK1) and a mutant (RBK1(Y379V,V381T); RBK1*) subunit of voltage-dependent potassium channels were injected into Xenopus oocytes.
(6) One rat strain (TAS) is susceptible to the anticoagulant and lethal effects of warfarin and the other two strains are homozygous for warfarin resistance genes from either wild Welsh (HW) or Scottish (HS) rats.
(7) No reversions to wild-type levels were observed in 555 heterozygous offspring of crosses between homozygous Campines and normals.
(8) The kinetics of endocytosis and recycling of the wild-type and mutant receptors were compared.
(9) Genetic regulation of the ilvGMEDA cluster involves attenuation, internal promoters, internal Rho-dependent termination sites, a site of polarity in the ilvG pseudogene of the wild-type organism, and autoregulation by the ilvA gene product, the biosynthetic L-threonine deaminase.
(10) In contrast, strains carrying the substitutions Ile-30----Phe, Gly-33----Leu, Gly-58----Leu, and Lys-34----Val and the Lys-34----Val, Glu-37----Gln double substitution were found to possess a coupled phenotype similar to that of the wild type.
(11) With one exception, the mutant control regions showed elevated beta-lactamase activity in comparison to the wild-type.
(12) Intercistronic complementation of these mutants with pm1493 and dl121, two SV40 mutants that are defective in agnoprotein but encode wild-type T antigen, results in an increased synthesis of agnoprotein in the infected cells.
(13) For example, stem pairing with a sequence other than wild-type resulted in normal protein binding in vitro but derepression of protein synthesis in vivo.
(14) Phage lysates of wild-type cells are capable of transducing auxotrophs of strain 78 to prototrophy at frequencies ranging from 0.3 x 10(-7) to 34 x 10(-7) per plaque-forming unit adsorbed.
(15) The mutant spores are pleomorphic and differ both in shape and size from the wild-type spores.
(16) Addition of streptomycin restores much of the wild-type behaviour.
(17) She read geography at Oxford, where Benazir Bhutto (a future prime minister of Pakistan, assassinated in 2007) introduced May to her future husband, Philip May: "I hate to say this, but it was at an Oxford University Conservative Association disco… this is wild stuff.
(18) A plasmid carrying this mutation, along with wild-type genes encoding the c and b subunits, was unusual in that it failed to complement a chromosomal c-subunit mutation on succinate minimal medium.
(19) Using allozymes as the genetic probe, data are presented which show that wild Drosophila buzzatii females and males engaged in copulation mate at random.
(20) Intact wild-type cells, or those of a mutant in which the core region of the lipopolysaccharide was absent, were equally resistant to pronase treatment.