(v. t.) To load or fill to excess; to load too heavily.
(n.) An excessive load; the excess beyond a proper load.
Example Sentences:
(1) By means of rapid planar Hill type antimony-bismuth thermophiles the initial heat liberated by papillary muscles was measured synchronously with developed tension for control (C), pressure-overload (GOP), and hypothyrotic (PTU) rat myocardium (chronic experiments) and after application of 10(-6) M isoproterenol or 200 10(-6) M UDCG-115.
(2) In iron-overloaded patients with primary haemochromatosis, there was inappropriately high uptake of iron by the biopsy specimens.
(3) The patient presented urgently for Caesarean section, with fluid overload and worsening thrombocytopaenia.
(4) Al hepatocytes overload appeared only in nuclei and not in nuclei and not in lysosomes, contrarily to chronic intoxications.
(5) Fluid overload, which could have been caused by the hyperosmolar properties of dextran, worsened progressively as fluids were drawn from the interstitial space and urine output was reduced.
(6) There were no significant differences between the mean levels of peak blood pressures (systolic, diastolic and mean), degree of fluid overload, and fractional sodium excretion in the 2 groups.
(7) Persisting diastolic dysfunction with a substantial rise in left ventricular filling pressure can be observed during dynamic exercise in postoperative patients with preoperative severe pressure overload hypertrophy.
(8) The 8 men and 3 women were clinically stable, were known to be compliant, and had no clinical evidence of aluminum overload; they were not receiving vitamin D supplements; and they had been on dialysis for an average of 65.6 months (range: 13-188 months).
(9) Wilson disease is due to a genetically determined impairment of copper excretion from liver into bile resulting in copper overload of the organism.
(10) There was no change in the sarcolemmal Mg2+ -ATPase of the left or right ventricle for the whole duration (3 to 9 months) of left ventricular pressure overload.
(11) These experimental results demonstrate that aluminium interferes with iron absorption and iron transfer, and suggest that these mechanisms may be responsible for maintaining and even increasing the anaemia observed in aluminium overload.
(12) When a high dose of the complex was administered, an overloading with hemosiderin of macrophages and hepatocytes was noticed.
(13) The subsequent accumulation of Na+ in the cell Na(+)-Ca2+ exchange, which can ultimately result in intracellular Ca2+ overload, contractile dysfunction and damage.
(14) If overloaded, these areas are subject to "cervical cratering," a common prelude to implant failure.
(15) The rationale for the inclusion of Mg in cardioplegic solutions therefore lies not in its cardioplegic properties, but in its ability to influence other cellular events such as the loss of Mg and K and perhaps to counter the detrimental effects of ischemia by antagonizing calcium (Ca) overload.
(16) Cardiac hypertrophy due to a chronic hemodynamic overload is accompanied by isoformic changes of two proteins of the thick filament of the sarcomere, myosin, and creatine phosphokinase.
(17) Age, gender and laboratory markers of iron overload did not differentiate patients with cardiac dysfunction (group 1) from those without cardiac dysfunction (group 2).
(18) Severe overloading can increase microdamage alarmingly, its repair by BMUs too, and can cause woven bone formation, anarchic resorption and a regional acceleratory phenomenon.
(19) Thus, it appears that the increased expression of the regulatory MLC2 gene in SHR atrial cells is a predetermined event, which, most likely, participates in functional adaptation of the myocardium in response to pressure overload and subsequent hypertrophy.
(20) To help resolve the issue of contractile function in volume overload hypertrophy, we examined ventricular function in a recently described model of severe chronic experimental mitral regurgitation.
Overlord
Definition:
(n.) One who is lord over another or others; a superior lord; a master.
Example Sentences:
(1) What he liked best was to talk to the cricket pro, Bert Wensley, formerly of Sussex, about such heroes as Maurice Tate, Duleepsinhji and HT Bartlett, and to encourage Bert to enlarge on his reasons for describing Sir Home Gordon, Bart, the overlord of Sussex cricket, as a "shit" - the first time we heard that word.
(2) It was launched on Wednesday with a party at the Mandarin Oriental hotel next door – an event so glittering that Formula One overlord Bernie Ecclestone was in attendance and überchef Heston Blumenthal did the catering.
(3) Believe the hype and he was a cross between a mafioso overlord and "HRH Victor Meldrew" (the epithet is David Starkey's).
(4) If the oligarchs of Silicon Valley feel empowered to sink outlets that they disagree with, our robot overlords will be here sooner than we think.
(5) Deliciously, The Internship is distributed by Searchlight's corporate overlord, 21st Century Fox.
(6) A year would have been the sort of seemly distance that might permit us to stop worrying and love our all-powerful tech overlords again.
(7) Bear that in mind while the feral overlords, with no real life experience, steal from the poor to bail out the rich.
(8) Seeing as I've already broken the fashion ranks by revealing the Great 57th Birthday Denim Swag Haul, I shall further anger my style overlords by confessing I strongly disagree with this rule.
(9) Instead of being a geeky orphan with money problems, the new Peter Parker (played by Andrew Garfield) was set up as a brooding teen (still with money problems) whose lack of mum and dad is linked in some mysterious manner to the seemingly omnipotent Oscorp and its shadowy overlord.
(10) She will be our discount dictator, perhaps, when her permatanned, pouting overlord has annexed us as a puppet state.
(11) Humans are part of nature, not its overlords, and caring for ourselves and for nature is inseparable in caring for our common home.
(12) Chinese people's long-standing animus toward their erstwhile colonial overlord is, of course, very real.
(13) As the US disengaged, Iran stepped in and, in the years since the US withdrawal, has acted as an overlord in neighbouring Iraq.
(14) This is entirely unfair to This Is 40 , no matter what one thinks of Apatow and his current status as Total Overlord of American Comedy.
(15) He will remain editor-in-chief, which he says will be more than a titular role, but plans to be an "enabler" rather than an overlord.
(16) Take out the results against the Bundesliga’s southern overlords and you’ll get an average points return against the 16 others in the league that has markedly decreased from 2.34 (2011-12) to 2 (2012-13) and 2.1 (2013-14).
(17) Its fate, and its chaotic confrontation with the eurozone’s overlords, is going to shape all of Europe’s future.
(18) On the eve of the 70th anniversary of the launch of Operation Overlord , Livingston has detailed memorabilia relating to the allied commander and the wartime president Franklin D Roosevelt , as well as other White House-related and sporting items.
(19) "I, for one, welcome our new computer overlords," Jennings wrote next to his last answer, displaying one human quality conspicuously absent in Watson – a sense of humour.
(20) My Dalek is not fit to serve at the court of his mighty citrus overlord.