(a.) Not covert; open; public; manifest; as, an overt act of treason.
Example Sentences:
(1) None of the animals injected with either CD4+ or CD8+ T cells became overtly diabetic during the 30 days of observation whereas 8 of 23 mice inoculated with a mixture of the two subsets developed glycosuria and hyperglycemia.
(2) In contrast, albino rats and rabbits failed to succumb to overt disease by subcutaneous and intraperitoneal routes of inoculation.
(3) Overt hemorrhage, major or minor, was assessed clinically.
(4) The recorded APs were further subdivided into those exhibiting consistent antegrade conduction during sinus rhythm (overt APs: 50 left APs, eight right APs), those exhibiting intermittent antegrade conduction (intermittent APs: six left APs, two right APs), and those exhibiting only retrograde conduction (concealed APs: 33 left APs, two right APs).
(5) Of 55 new open reading frames analysed by gene disruption, three are essential genes; of 42 non-essential genes that were tested, 14 show some discernible effect on phenotype and the remaining 28 have no overt function.
(6) It is theoretically possible that in patients with overt CHF, drug treatment may not alter prognosis.
(7) This is suggested by the fact that patients with overt hyperparathyroidism are protected from developing aluminum-related bone disease even when they are given large parenteral loads of aluminum.
(8) Cable news channels like Fox News and CNN carried the address, and some of the networks carried it on their digital platforms, but a network insider told Politico on Thursday the speech’s content was too “overtly political” to broadcast.
(9) These do not concur with clinical experience but the figures for overt resistance, at 39% and 69%, correspond with expected non-responders to these regimes.
(10) It is important to appreciate that metabolic alterations are more severe in those patients with overt pulmonary insufficiency and that the metabolic response does not appear to be directly related to the severity of skeletal injury.
(11) Criteria for selective measurement of cholesterol concentration in cardiovascular screening programmes identify about three quarters of patients with the clinically overt condition.
(12) The present study demonstrated that delayed administration of a marine lipid diet, 25% menhaden oil (MO) by weight, until after the onset of overt renal disease, also resulted in significant improvement in rates of mortality, proteinuria, and histologic evidence of glomerular injury, compared with control animals fed a diet that contained mostly saturated fatty acids, 25% beef tallow.
(13) A more aggressive treatment with cytostatic drugs is suggested in the progressive form of the disease of younger patients and in patients with overt acute leukaemia.
(14) This study includes nine patients with a megakaryoblastic crisis in chronic myeloid leukemia (CML), four with acute megakaryoblastic leukemia (AM) and three with myeloid dysplasia later evolving into overt acute leukemia.
(15) In this study we measured plasma carnitine in a third group, alcoholic patients without overt liver disease.
(16) IDDM patients with incipient and overt nephropathy have been found to exhibit an overactivity of RBC sodium-lithium countertransport.
(17) To investigate atrial natriuretic factor (ANF) and its relationship to the renin system in diabetes, we measured plasma immunoreactive ANF and plasma renin activity (PRA) in 27 non-ketotic diabetic patients without evidence of cardiac or overt renal disease, and compared them with 26 age- and sex-matched normal subjects.
(18) Failure to isolate bacteria and the lack of overt inflammation during periods of remission suggested that the bacteria were not in the gland cistern but within gland tissue.
(19) TRH-TSH test enables to detect disorders of hypophyseal-thyroidal regulation characteristic for both overt and masked hyperthyroidism.
(20) Using two different assay systems to distinguish between overt and inner forms of carnitine palmitoyl transferase (CPT, EC 2.3.1.21) of intact guinea-pig liver mitochondria, we have shown that the hypoglycemic agent 2-(3-methylcinnamylhydrazono)-propionate (BM 42.304) inhibits the activity of carnitine-acylcarnitine translocase of liver mitochondria.
Subtle
Definition:
(superl.) Sly in design; artful; cunning; insinuating; subtile; -- applied to persons; as, a subtle foe.
(superl.) Cunningly devised; crafty; treacherous; as, a subtle stratagem.
(superl.) Characterized by refinement and niceness in drawing distinctions; nicely discriminating; -- said of persons; as, a subtle logician; refined; tenuous; sinuous; insinuating; hence, penetrative or pervasive; -- said of the mind; its faculties, or its operations; as, a subtle intellect; a subtle imagination; a subtle process of thought; also, difficult of apprehension; elusive.
(superl.) Smooth and deceptive.
Example Sentences:
(1) As a group, the three mammalian proteins resemble bovine serum conglutinin and behave as lectins with rather broad sugar specificities directed at certain non-reducing terminal N-acetylglucosamine, mannose, glucose and fucose residues, but with subtle differences in fine specificities.
(2) But it will be a subtle difference, because it's already abundantly clear there's no danger of the war being suddenly forgotten, or made to seem irrelevant to our sense of what Europe and the world has to avoid repeating.
(3) Communicating sustainability is a subtle attempt at doing good Read more And yet, in environmental terms it is infinitely preferable to prevent waste altogether, rather than recycle it.
(4) If, indeed, there is an immunologic basis for pre-eclampsia, it is more subtle than the methodology used in this study is capable of detecting.
(5) Subtle differences between Chicago urban and Grand Forks rural climates are reflected in arthritic subjects' degree of pain and their perception of pain-related stress.
(6) Critical in this understanding are the subtle changes that occur in the individual patient, reflecting the natural history of the disease or response to its treatment.
(7) Subtle cognitive deficits in Inferential Reading Comprehension were detected when Reading Vocabulary was at or better than a twelfth grade level.
(8) This histochemical difference corresponded to more subtle differences in Nissl and myelin staining patterns, and suggests further structural subdivisions of potential functional significance.
(9) Thus, luciferase transcriptional fusions can detect subtle variations in initial rates of gene expression in a real-time, nondestructive assay.
(10) The binding of [3H]PAF to washed human platelets indicated subtle changes between Days 2 and 4, which became more noticeable by Day 6.
(11) In this study the temperature dependence of the reactivity of aldolase SH groups is investigated in order to detect subtle changes in the enzyme conformation.
(12) The crucial issue of whether subtle behavioral, intellectual, and developmental impairment occurs in young children, as a result of lead-induced CNS damage is discussed in detail.
(13) Historically, what made SNL’s campaign coverage so necessary was its ability to highlight the subtle absurdities of the election and exaggerate the ridiculous.
(14) It is believed that by looking at such subtle shape differences an understanding of what it means morphologically for a primate to be either more or less arboreal may be achieved.
(15) The current magnetic resonance imaging system with computerized image processing is a sensitive and simple method for evaluation of subtle parenchymal changes of the brain.
(16) Fundus examination disclosed a subtle cherry red spot bilaterally.
(17) Ependymal cells developed luminal fronds that projected into the ventricle and the subpial glia displayed a very subtle gliosis in the form of thin multi-laminated processes.
(18) The rapidity of obtaining the results (within one hour), the complete absence of untoward reactions to the radiopharmaceuticals, the much lower frequency of subtle or indeterminate results, the ability to render useful information in the presence of moderate jaundice and the lack of interference from overlying intestinal contents establishes these radionuclide agents as superior to both radiographic oral and intravenous cholangiography in the investigation of the acute abdomen.
(19) Moreover, subtle improvements observed in earlier investigations were not confirmed.
(20) Various compounds show subtle but significant differences in blood clearance, excretion, and soft-tissue uptake.