(1) The following conclusions emerge: (i) when the 3' or the 3' penultimate base of the oligonucleotide mismatched an allele, no amplification product could be detected; (ii) when the mismatches were 3 and 4 bases from the 3' end of the primer, differential amplification was still observed, but only at certain concentrations of magnesium chloride; (iii) the mismatched allele can be detected in the presence of a 40-fold excess of the matched allele; (iv) primers as short as 13 nucleotides were effective; and (v) the specificity of the amplification could be overwhelmed by greatly increasing the concentration of target DNA.
(2) She added: “We will continue to act upon the overwhelming majority view of our shareholders.” The vote was the second year running Ryanair had suffered a rebellion on pay.
(3) T cells admixed in the germinal centers were overwhelmingly of the T-helper type.
(4) Unfortunately for the governor, he could win both states and still face the overwhelming likelihood of failure if he doesn't take Ohio, where the poll found Obama out front 51-43.
(5) In Britain, the European election is overwhelmingly seen through the prism of domestic politics.
(6) Photograph: Christopher Thomond for the Guardian Asked if Watson should seek to refresh his mandate after Corbyn’s overwhelming victory among members, McCluskey added: “Well, if Tom wants to try to refresh his mandate it would be interesting to see what happens.” Watson said it was time “to be proud of our party”, because the Conservatives were beatable and the prime minister, Theresa May, could call an election any time.
(7) The government acknowledged it had been overwhelmed by the devastation from the deadliest quake in Nepal in over 80 years.
(8) He made me laugh and cry, and his courage in writing about what he was going through was sometimes quite overwhelming.
(9) Although alpha 1-antiprotease (alpha 1-AP) binds and inactivates NE and is the major antielastase of the lower respiratory tract, antielastase defenses may be overwhelmed in CF, leading to progressive lung damage.
(10) And HAP has shown that the key finding that debt slows growth was driven overwhelmingly by the exclusion of four years of data from New Zealand.
(11) Cathepsin D-like acid proteinase existed overwhelmingly in the mucosal layer and was hardly detected in the gastric juice.
(12) Hence, reaction of chemical carcinogen with nuclear DNA is possible only when the cell is overwhelmed leading to cell death, or following a temporary breach of the nuclear membrane control points, but the DNA damage in the latter is totally reparable.
(13) The facts are clear: the overwhelming majority of EU citizens in Britain are contributors, not freeloaders.” But that was not the official position of any of the parties involved, so it went mostly unsaid.
(14) Of 54 patients with poor-grade aneurysms, ventriculostomy was placed in 47 (87.0%) and yielded high ICP's in the overwhelming majority, with the mean ICP being 40.2 cm H2O.
(15) There is overwhelming evidence, today, that such factors are involved in the manifestation of acute as well as chronic, non-specific as well as well as specific inflammation.
(16) Mobile phone networks, overwhelmed by demand, were down for hours, with authorities advising people to use email or text messages instead.
(17) The immunity was enacted by an overwhelming bipartisan vote, with the support of leading Democrats including Barack Obama, who had promised - when seeking his party's nomination - to filibuster any bill that contained retroactive telecom immunity.
(18) There’s an overwhelming sadness among kids like that who have been kept there for a very long time.
(19) Panic attacks would overwhelm her periodically and she experienced regular “ scanxiety ” – the feelings of dread that grip patients before new tests.
(20) In the meantime, Malaysia Airlines’ overwhelming focus will be the same as it has been from the outset – to provide the families with a comprehensive support programme.
Panic
Definition:
(n.) A plant of the genus Panicum; panic grass; also, the edible grain of some species of panic grass.
(a.) Extreme or sudden and causeless; unreasonable; -- said of fear or fright; as, panic fear, terror, alarm.
(a.) A sudden, overpowering fright; esp., a sudden and groundless fright; terror inspired by a trifling cause or a misapprehension of danger; as, the troops were seized with a panic; they fled in a panic.
(a.) By extension: A sudden widespread fright or apprehension concerning financial affairs.
Example Sentences:
(1) The findings are more consistent with those in studies of panic disorder.
(2) The sound of the ambulance frightened us, especially us children, and panic gripped the entire community: people believe that whoever is taken into the ambulance to the hospital will die – you so often don’t see them again.
(3) Lactate-induced anxiety and symptom attacks without panic were seen more often in the groups with panic attacks, but a full-blown panic attack was provoked in only four subjects, all belonging to the groups with a history of panic attacks.
(4) Evidence of the industrial panic surfaced at Digital Britain when Sly Bailey, the chief executive of Trinity Mirror, suggested that national newspaper websites that chased big online audiences have "devalued news" , whatever that might mean.
(5) Panic disorder subjects showed a negative relationship between pulmonary function and hyperventilation symptoms, suggesting a heightened sensitivity to, and discomfort with, sensations associated with normal pulmonary function.
(6) The occurrence of secondary MDE was related to the length of time subjects were ill with panic disorder.
(7) This unbearable situation leads to panic and auto-sensory deprivation.
(8) Patients with temporal lobe abnormalities were significantly younger at the onset of panic disorder and had more panic attacks compared with patients with normal MRI scans (p less than .05).
(9) Sometimes it can seem as if the history of the City is the history of its crises and disasters, from the banking crisis of 1825 (which saw undercapitalised banks collapse – perhaps the closest historic parallel to the contemporary credit crunch), through the Spanish panic of 1835, the railway bust of 1837, the crash of Overend Gurney, the Kaffir boom, the Westralian boom, the Marconi scandal, and so on and on – a theme with endless variations.
(10) The incidence of cardiac perceptions was about the same in both groups, but only subjects with panic attacks reported anxiety associated with such perceptions.
(11) Future work on biochemical causes of, and pharmacological treatments for panic attacks should take account of such factors.
(12) He was the peaceful activist whose sudden disappearance into a phalanx of riot police on a Baltimore street sparked a viral panic.
(13) Unresolved etiological issues requiring clarification in the near future include the following: (1) Are stressful events important in the development of panic, or are they more incidentally related?
(14) The results provide support for cognitive mediation in the "panic" component of spontaneous panic attacks.
(15) Most panics surged out of a pre-existing plateau of tonic anxiety which lasted most of the day.
(16) Advancing to the edge of the Ireland penalty area, he tries to pick out Thierry Henry, but his pass is wayward and a panic-stricken, back-pedalling Ireland defence clears.
(17) Meantime, while we wouldn't want to you panic, Owen Gibson says vuvuzelas may be on their way to the Premier League .
(18) Some were less fortunate, but panic has given way to a Balkan pride and resilience.
(19) The findings are discussed in relation to conditions such as somatisation disorder, the syndrome of chronic unexplained pain, and panic disorder.
(20) The Scottish defence did well not to panic, there, as Walcott's twinkle-toed run had penalty written all over it.