(1) The following conclusions emerge: (i) when the 3' or the 3' penultimate base of the oligonucleotide mismatched an allele, no amplification product could be detected; (ii) when the mismatches were 3 and 4 bases from the 3' end of the primer, differential amplification was still observed, but only at certain concentrations of magnesium chloride; (iii) the mismatched allele can be detected in the presence of a 40-fold excess of the matched allele; (iv) primers as short as 13 nucleotides were effective; and (v) the specificity of the amplification could be overwhelmed by greatly increasing the concentration of target DNA.
(2) She added: “We will continue to act upon the overwhelming majority view of our shareholders.” The vote was the second year running Ryanair had suffered a rebellion on pay.
(3) T cells admixed in the germinal centers were overwhelmingly of the T-helper type.
(4) Unfortunately for the governor, he could win both states and still face the overwhelming likelihood of failure if he doesn't take Ohio, where the poll found Obama out front 51-43.
(5) In Britain, the European election is overwhelmingly seen through the prism of domestic politics.
(6) Photograph: Christopher Thomond for the Guardian Asked if Watson should seek to refresh his mandate after Corbyn’s overwhelming victory among members, McCluskey added: “Well, if Tom wants to try to refresh his mandate it would be interesting to see what happens.” Watson said it was time “to be proud of our party”, because the Conservatives were beatable and the prime minister, Theresa May, could call an election any time.
(7) The government acknowledged it had been overwhelmed by the devastation from the deadliest quake in Nepal in over 80 years.
(8) He made me laugh and cry, and his courage in writing about what he was going through was sometimes quite overwhelming.
(9) Although alpha 1-antiprotease (alpha 1-AP) binds and inactivates NE and is the major antielastase of the lower respiratory tract, antielastase defenses may be overwhelmed in CF, leading to progressive lung damage.
(10) And HAP has shown that the key finding that debt slows growth was driven overwhelmingly by the exclusion of four years of data from New Zealand.
(11) Cathepsin D-like acid proteinase existed overwhelmingly in the mucosal layer and was hardly detected in the gastric juice.
(12) Hence, reaction of chemical carcinogen with nuclear DNA is possible only when the cell is overwhelmed leading to cell death, or following a temporary breach of the nuclear membrane control points, but the DNA damage in the latter is totally reparable.
(13) The facts are clear: the overwhelming majority of EU citizens in Britain are contributors, not freeloaders.” But that was not the official position of any of the parties involved, so it went mostly unsaid.
(14) Of 54 patients with poor-grade aneurysms, ventriculostomy was placed in 47 (87.0%) and yielded high ICP's in the overwhelming majority, with the mean ICP being 40.2 cm H2O.
(15) There is overwhelming evidence, today, that such factors are involved in the manifestation of acute as well as chronic, non-specific as well as well as specific inflammation.
(16) Mobile phone networks, overwhelmed by demand, were down for hours, with authorities advising people to use email or text messages instead.
(17) The immunity was enacted by an overwhelming bipartisan vote, with the support of leading Democrats including Barack Obama, who had promised - when seeking his party's nomination - to filibuster any bill that contained retroactive telecom immunity.
(18) There’s an overwhelming sadness among kids like that who have been kept there for a very long time.
(19) Panic attacks would overwhelm her periodically and she experienced regular “ scanxiety ” – the feelings of dread that grip patients before new tests.
(20) In the meantime, Malaysia Airlines’ overwhelming focus will be the same as it has been from the outset – to provide the families with a comprehensive support programme.
Smash
Definition:
(v. t.) To break in pieces by violence; to dash to pieces; to crush.
(v. i.) To break up, or to pieces suddenly, as the result of collision or pressure.
(n.) A breaking or dashing to pieces; utter destruction; wreck.
(n.) Hence, bankruptcy.
Example Sentences:
(1) I can't wait to see what Christie and her patriarchy-smashing pals do next.
(2) At one, in the Gun and Dog pub in Leeds on Tuesday, a witness described how the meeting descended into chaos when one of the rebels smashed a glass and threatened to attack Griffin supporter Mark Collett.
(3) Shaker Aamer , a Saudi who lived in London before travelling to Afghanistan, has given a statement to one of his lawyers in which he says British intelligence officers were present while Americans beat him and smashed his head against a wall.
(4) Bloody odd combination but those Orange Foam Headphones would blast those magnificent records into my developing brain over and over again" chernypyos – Björk's Human Behavior and Sinead O'Connor's Fire On Babylon: "bjork's 'human behavior' and sinead o'connor's "fire on babylon" oddly stick in my head from that one evening walking in the woods, breathing the damp air, and feeling pleasantly invisible" Pyromancer – REM – Automatic for the People Blood Sugar Sex Magic Pearl Jam - Vs RATM's first album Portishead Maxinquaye by Tricky Manic Street Preachers – Gold Against the Soul Smashing Pumpkins, Siamese Dream "I used to go to the local library and take out a CD (50p for 3 weeks!
(5) It may have been like punk never ‘appened, but you caught a whiff of the movement’s scorched earth puritanism in the mocking disdain with which Smash Hits addressed rock-star hedonism.
(6) 8.51pm GMT Falcons 27 - Seahawks 21, 3:35 4th of quarter The smash mouth Falcons are back on first down, Turner has 12 more yards.
(7) Kuyt tries to smash a first-time sidefoot goalwards from the penalty spot, but doesn't connect properly, and Garay blocks anyway.
(8) I thought he'd smash it somewhere near the corner and hope it would go through, and he's left‑footed.
(9) Smashed windows and bomb damage visible at the front of the station.
(10) When I had that keyhole surgery, I thought: ‘Maybe, if I come back, it won’t be to that top level.’ But with the support I have been getting from my coach, family and friends, I think that really motivated me to come back strong.” Kenya is more famed for its distance runners and steeplechasers than its hurdlers, but the country was left celebrating a surprise gold medal in the 400m hurdles when Nicholas Bett powered home from lane nine to smash his personal best to win in 47.79sec.
(11) In one of his lunch breaks with Sleep, he told him that he had been tortured by the army, smashed over the head with the butt of an AK47 and left for dead.
(12) Cops were smashing people with bicycles and nightsticks."
(13) The former concept has been smashed by the digital economy, which helped enable 1.2 million Britons to switch banks last year.
(14) Barra’s main rivals in the single-speed category were Willo and a rider nicknamed Neu York, representing the Gorilla Smash Squad.
(15) Manchester United coach ‘smashed up’ on way to Upton Park Read more The equation had been simple enough.
(16) In December he smashed apart the Roman forces in the north, assisted by his awesome elephants, the tanks of classical warfare.
(17) The ceremony also produced the most retweeted photograph ever, with Ellen DeGeneres’ “selfie” attracting more than 2m retweets to smash Barack Obama’s record .
(18) Damn them and their hands for what they are doing.” Facebook Twitter Pinterest The video, released on Thursday, showed men smashing up artefacts dating back to the seventh century BC Assyrian era, toppling statues from plinths, smashing them with a sledgehammer and breaking up a carving of a winged bull with a drill.
(19) Bauer Radio's Smash Hits saw the biggest dip in audience among the national digital commercial radio stations in the third quarter of 2009, dipping below the 1 million mark.
(20) (Has anyone come across a couple who have tried this successfully, without one smashing the bottle of wine across the other's forehead?