(1) The following conclusions emerge: (i) when the 3' or the 3' penultimate base of the oligonucleotide mismatched an allele, no amplification product could be detected; (ii) when the mismatches were 3 and 4 bases from the 3' end of the primer, differential amplification was still observed, but only at certain concentrations of magnesium chloride; (iii) the mismatched allele can be detected in the presence of a 40-fold excess of the matched allele; (iv) primers as short as 13 nucleotides were effective; and (v) the specificity of the amplification could be overwhelmed by greatly increasing the concentration of target DNA.
(2) She added: “We will continue to act upon the overwhelming majority view of our shareholders.” The vote was the second year running Ryanair had suffered a rebellion on pay.
(3) T cells admixed in the germinal centers were overwhelmingly of the T-helper type.
(4) Unfortunately for the governor, he could win both states and still face the overwhelming likelihood of failure if he doesn't take Ohio, where the poll found Obama out front 51-43.
(5) In Britain, the European election is overwhelmingly seen through the prism of domestic politics.
(6) Photograph: Christopher Thomond for the Guardian Asked if Watson should seek to refresh his mandate after Corbyn’s overwhelming victory among members, McCluskey added: “Well, if Tom wants to try to refresh his mandate it would be interesting to see what happens.” Watson said it was time “to be proud of our party”, because the Conservatives were beatable and the prime minister, Theresa May, could call an election any time.
(7) The government acknowledged it had been overwhelmed by the devastation from the deadliest quake in Nepal in over 80 years.
(8) He made me laugh and cry, and his courage in writing about what he was going through was sometimes quite overwhelming.
(9) Although alpha 1-antiprotease (alpha 1-AP) binds and inactivates NE and is the major antielastase of the lower respiratory tract, antielastase defenses may be overwhelmed in CF, leading to progressive lung damage.
(10) And HAP has shown that the key finding that debt slows growth was driven overwhelmingly by the exclusion of four years of data from New Zealand.
(11) Cathepsin D-like acid proteinase existed overwhelmingly in the mucosal layer and was hardly detected in the gastric juice.
(12) Hence, reaction of chemical carcinogen with nuclear DNA is possible only when the cell is overwhelmed leading to cell death, or following a temporary breach of the nuclear membrane control points, but the DNA damage in the latter is totally reparable.
(13) The facts are clear: the overwhelming majority of EU citizens in Britain are contributors, not freeloaders.” But that was not the official position of any of the parties involved, so it went mostly unsaid.
(14) Of 54 patients with poor-grade aneurysms, ventriculostomy was placed in 47 (87.0%) and yielded high ICP's in the overwhelming majority, with the mean ICP being 40.2 cm H2O.
(15) There is overwhelming evidence, today, that such factors are involved in the manifestation of acute as well as chronic, non-specific as well as well as specific inflammation.
(16) Mobile phone networks, overwhelmed by demand, were down for hours, with authorities advising people to use email or text messages instead.
(17) The immunity was enacted by an overwhelming bipartisan vote, with the support of leading Democrats including Barack Obama, who had promised - when seeking his party's nomination - to filibuster any bill that contained retroactive telecom immunity.
(18) There’s an overwhelming sadness among kids like that who have been kept there for a very long time.
(19) Panic attacks would overwhelm her periodically and she experienced regular “ scanxiety ” – the feelings of dread that grip patients before new tests.
(20) In the meantime, Malaysia Airlines’ overwhelming focus will be the same as it has been from the outset – to provide the families with a comprehensive support programme.
Subjugate
Definition:
(v. t.) To subdue, and bring under the yoke of power or dominion; to conquer by force, and compel to submit to the government or absolute control of another; to vanquish.
Example Sentences:
(1) Although he could be lovable, charming, whimsical, encouraging, and deeply devoted to his family, he subjugated the adult women in his household and at least one son to exploitation and abuse, demanding (and receiving from his wife and step-daughter) almost total abnegation of self.
(2) It is very disturbing that today's social customs allow Dr. Cornwell to advise that personal moral values should be subjugated to those of the community.
(3) If a Muslim candidate did not renounce such aspects of his or her faith, Carson said, “Why in fact would you take that chance?” Referring to criticism of his remark last weekend to NBC that he “would not advocate” a Muslim becoming president, Carson said: “I said anybody, doesn’t matter what their religious background, if they accept American values and principles and are willing to subjugate their religious beliefs to our constitution, I have no problem with them.” Article VI of the US constitution states: “No religious Test shall ever be required as a Qualification to any Office or public Trust under the United States.” The first amendment to the constitution says: “Congress shall make no law respecting an establishment of religion, or prohibiting the free exercise thereof …” Carson is a member of the Seventh Day Adventist Church.
(4) The next conquest by William in 1066 crushed Anglo-Saxon England, but that in turn would produce the idea of “the Norman yoke”, which had supposedly subjugated the English people.
(5) Egypt's breadbasket is littered with the remnants of old colonisers, from the Romans to the Germans, and today its 50 million inhabitants jostle for space among the crumbling forts and cemeteries of those who sought to subjugate them in the past.
(6) The judiciary branch, according to these three laws, would become subjugated to the executive,” said Ewa Łętowska, a professor at Poland’s Institute of Legal Sciences and a former judge who served on the country’s constitutional tribunal and the supreme administrative court.
(7) When psychotherapy is viewed as inherently a change-facilitating process, subjugated to and oriented toward such events, the therapist's function is catalytic rather than analytic.
(8) With the Somali women who were the antithesis of the stereotyped, subjugated Muslim female – strong, proud, fighters to the end.
(9) LaPierre says look at the Second Amendment: "They had lived under the tyranny of King George and they wanted to make sure that these people in this new country would never be subjugated to tyranny... Then LaPierre says if there's an earthquake people need guns: "The only way they're going to be able to protect themselves in the cold, in the dark, when they're vulnerable, is with a gun."
(10) And yet the latest criticism from Brussels inspires a rightwing magazine cover showing European leaders wearing Nazi uniform: “Once again they want to subjugate Poland.” The PiS government is “anti-European”.
(11) Although the modern medical culture has originated in the West, it has gradually spread to all parts of the world, subjugating other kinds of medical knowledge and other attitudes to dying and death.
(12) Has the epidemic mass rape in Congo got something to do with the country's own history, the result of many years of subjugation, played back?
(13) It is no more justifiable than saying that the only future which religious Jews - as Jews - can envision is one in which non-Jews live in complete slavery and subjugation: a claim often made by anti-semites based on highly selective passages from the Talmud .
(14) His own daughter, a glamorous lawyer, is certainly no subjugated eastern woman.
(15) They are those who do not want Britain to look after its own economic interests and wants it to be subjugated to them for ever."
(16) And so they came by the thousands from every corner of our country, men and women, young and old, blacks who longed for freedom and whites who could no longer accept freedom for themselves while witnessing the subjugation of others.
(17) These connections survived Moon's increasingly embarrassing activities – his sermons dwelling on the "sexual organs", his description of American women as descended from prostitutes, family scandals, Rabbinic court condemnation for antisemitism and a vow to "conquer and subjugate the world".
(18) As a fellow Rhodes scholar and an African woman, I frequently get asked why, in the face of Rhodes's bloody and destructive quest to subjugate an entire generation of my people, I would accept money from a trust set up in his name.
(19) During subjugation and inertial feeding the skull remains ventroflexed.
(20) Asked in 2005 to elaborate on the meaning of the band's lyrics, Page replied: "The topics vary from sociological issues, religion, and how the value of human life has been degraded by being submissive to tyranny and hypocrisy that we are subjugated to."