(1) The following conclusions emerge: (i) when the 3' or the 3' penultimate base of the oligonucleotide mismatched an allele, no amplification product could be detected; (ii) when the mismatches were 3 and 4 bases from the 3' end of the primer, differential amplification was still observed, but only at certain concentrations of magnesium chloride; (iii) the mismatched allele can be detected in the presence of a 40-fold excess of the matched allele; (iv) primers as short as 13 nucleotides were effective; and (v) the specificity of the amplification could be overwhelmed by greatly increasing the concentration of target DNA.
(2) She added: “We will continue to act upon the overwhelming majority view of our shareholders.” The vote was the second year running Ryanair had suffered a rebellion on pay.
(3) T cells admixed in the germinal centers were overwhelmingly of the T-helper type.
(4) Unfortunately for the governor, he could win both states and still face the overwhelming likelihood of failure if he doesn't take Ohio, where the poll found Obama out front 51-43.
(5) In Britain, the European election is overwhelmingly seen through the prism of domestic politics.
(6) Photograph: Christopher Thomond for the Guardian Asked if Watson should seek to refresh his mandate after Corbyn’s overwhelming victory among members, McCluskey added: “Well, if Tom wants to try to refresh his mandate it would be interesting to see what happens.” Watson said it was time “to be proud of our party”, because the Conservatives were beatable and the prime minister, Theresa May, could call an election any time.
(7) The government acknowledged it had been overwhelmed by the devastation from the deadliest quake in Nepal in over 80 years.
(8) He made me laugh and cry, and his courage in writing about what he was going through was sometimes quite overwhelming.
(9) Although alpha 1-antiprotease (alpha 1-AP) binds and inactivates NE and is the major antielastase of the lower respiratory tract, antielastase defenses may be overwhelmed in CF, leading to progressive lung damage.
(10) And HAP has shown that the key finding that debt slows growth was driven overwhelmingly by the exclusion of four years of data from New Zealand.
(11) Cathepsin D-like acid proteinase existed overwhelmingly in the mucosal layer and was hardly detected in the gastric juice.
(12) Hence, reaction of chemical carcinogen with nuclear DNA is possible only when the cell is overwhelmed leading to cell death, or following a temporary breach of the nuclear membrane control points, but the DNA damage in the latter is totally reparable.
(13) The facts are clear: the overwhelming majority of EU citizens in Britain are contributors, not freeloaders.” But that was not the official position of any of the parties involved, so it went mostly unsaid.
(14) Of 54 patients with poor-grade aneurysms, ventriculostomy was placed in 47 (87.0%) and yielded high ICP's in the overwhelming majority, with the mean ICP being 40.2 cm H2O.
(15) There is overwhelming evidence, today, that such factors are involved in the manifestation of acute as well as chronic, non-specific as well as well as specific inflammation.
(16) Mobile phone networks, overwhelmed by demand, were down for hours, with authorities advising people to use email or text messages instead.
(17) The immunity was enacted by an overwhelming bipartisan vote, with the support of leading Democrats including Barack Obama, who had promised - when seeking his party's nomination - to filibuster any bill that contained retroactive telecom immunity.
(18) There’s an overwhelming sadness among kids like that who have been kept there for a very long time.
(19) Panic attacks would overwhelm her periodically and she experienced regular “ scanxiety ” – the feelings of dread that grip patients before new tests.
(20) In the meantime, Malaysia Airlines’ overwhelming focus will be the same as it has been from the outset – to provide the families with a comprehensive support programme.
Sweeping
Definition:
(p. pr. & vb. n.) of Sweep
(a.) Cleaning off surfaces, or cleaning away dust, dirt, or litter, as a broom does; moving with swiftness and force; carrying everything before it; including in its scope many persons or things; as, a sweeping flood; a sweeping majority; a sweeping accusation.
Example Sentences:
(1) Now, as the Senate takes up a weakened House bill along with the House's strengthened backdoor-proof amendment, it's time to put focus back on sweeping reform.
(2) One man has died in storms sweeping across the UK that have brought 100-mile-an-hour winds and led to more than 50 flood warnings being issued with widespread disruption on the road and rail networks in much of southern England and Scotland.
(3) That’s a criticism echoed by Democrats in the Senate, who issued a report earlier this month criticising Republicans for passing sweeping legislation in July to combat addiction , the Comprehensive Addiction and Recovery Act (Cara), but refusing to fund it.
(4) he asked in a low voice, referring to the Sunni insurgents sweeping across northern Iraq .
(5) The Florida senator on Wednesday signed on to legislation that would delay the implementation of the sweeping surveillance reforms passed by Congress under the USA Freedom Act.
(6) The building blocks were laid out in a sweeping document presented by Van Rompuy and colleagues earlier this week that included sharing debt in the form of jointly issued eurobonds.
(7) For once, however, Beckham's timing was out, and his tenure has seen the club win nothing, and a new regime led by austere Italian Fabio Capello sweep away the superstar culture.
(8) Behind the broad sweep of pessimism, it is worth thinking about how the "eurozone in crisis" story could eventually improve.
(9) As fighter jets screamed overhead and tanks churned up the sand, it looked and sounded like the violent protests sweeping the Middle East had spread to the wealthy emirate of Abu Dhabi.
(10) Compulsory national testing for four- and five-year-olds in England from 2016 is to be introduced as part of sweeping changes being proposed to early years and primary education.
(11) In addition, the sine-sweep responses show quite different frequency characteristics in respect of depolarization and repolarization.
(12) The sweeping proposals are a sizeable step up in scale and urgency for a mayor who has for years emphasised the threat climate change poses to the city, which has 520 miles of coastline.
(13) Blinded by a series of sweeping victories, he forgot that the public saw in him not only stability, but also a hope for decentralisation and redistribution of power.
(14) In post-spike averages of 1000-10,000 sweeps, no evidence of reflex excitation of the homonymous motoneurone pool was detected.
(15) In 11 cases, barium examination of the upper gastrointestinal tract revealed prominent filling defects in the duodenal bulb and the duodenal sweep.
(16) Tom Tobler, a forecaster with MeteoGroup, the weather division of the Press Association, said: "Gusts of 50mph to 60mph are sweeping across south-west England, central England and Wales, which will see the worst of the windy weather.
(17) Three US senators announced bills on Thursday that proposed the most sweeping structural changes to the secret court that oversees the legal basis for surveillance activities since it was set up 35 years ago.
(18) A "sweep" bend was incorporated to avoid unwanted side effects at the second premolar.
(19) However, the military remains unable to shift Isis from its strongholds or reverse the gains the group made during a stunning sweep through Mosul and Tikrit that continues to pose a grave threat to Iraq's borders.
(20) She may have her own reasons, but if this view takes hold, it will have sweeping implications.