(n.) A discharge of fetid matter from the nostril, particularly if associated with ulceration of the soft parts and disease of the bones of the nose.
Example Sentences:
(1) Although the incidence of ozena is greatly diminished in the western world, it is still encountered rarely and merits the attention of the ENT specialist.
(2) Experiments on the active protection of mice from ozenous infection in its two forms, generalized (acute sepsis) and local (plantar infiltration), have demonstrated that immunity, induced by experimental heat-killed ozena vaccine (Klebsiella ozaenae strain 2211, antigens 02B:K4) introduced in a single injection, is characterized by sufficiently high intensity (the degree of protection increases up to 10,000-fold) and duration (at least 30 days).
(3) Primary atrophic rhinitis or ozena is a chronic nasal disease characterized by progressive atrophy of the nasal mucosa and underlying bone, accompanied by the formation of foul smelling, thick, dry crusts in the greatly enlarged nasal cavities.
(5) Hereditary, infectious, developmental, endocrine and nutritional factors have been implicated but the etiology of ozena still remains enigmatic.
(6) An osteoperiosteal flap taken from the anterior wall of the maxilla and pedicled on its periosteum was developed to narrow the nasal cavity of 15 patients with ozena.
(7) Its use in the inner nose to replace the cartilaginous septum or rebase the mucosa in ozena, however, cannot be recommended.
(8) Antibiotic sensitivity of 292 strains of Proteus, 60 strains of Ps, aeruginosa, 309 strains of S. aureus and 88 strains of S. epidermidis isolated from the upper respiratory tract of patients with scleroma and ozena was studied.
(9) Odor decreased in one patient, but K ozenae failed to clear.
(10) Hydroxylapatite was implanted under the mucosa of the nasal septum and the floor of the nasal cavity in four patients with ozena.
(11) K ozenae was cultured from the nasal cavity of three patients.
(12) Histopathologic features allow ozena to be distinguished from chronic non-specific hypertrophic rhinitis, which may have a cell-mediated immune basis underlying its pathogenesis.
(13) Biopsy material from 50 patients with a known clinical diagnosis of ozena was examined histopathologically.
(14) A critical evaluation of test results, immunological literature and some related challenge tests as to delayed reactions in human medicine are the reason for assuming the clinical symptoms of hypertrophy preceding ozena to be the clinical correlation to a type IV reaction.
(15) Antibacterial therapy in cases with scleroma and ozena should be directed not only against causative agents of the diseases but also against the microbes developing due to disbacteriosis.
(16) Before this decade, K. ozaenae was considered to be only a colonizer of the nasopharynx or a putative cause of ozena (atrophic rhinitis).
(17) Among many theories about the etiology of atrophic rhinitis with ozena, a reduced mucosal blood flow has been suggested, possibly caused by 'sympathetic spasm'.
(18) The organism most often associated with atrophic rhinitis is Klebsiella ozenae.
(19) In the second patient both odor and K ozenae disappeared.
(20) K ozaenae is generally considered an opportunist of low virulence and a respiratory tract colonizer implicated in ozena (atrophic rhinitis).