(interj.) An exclamation expressing disgust or contempt. See Bah.
(n.) A kind of stockaded intrenchment.
Example Sentences:
(1) In contrast, Leydig cells from rat testis contain monooxygenase systems which catalyze the metabolism of PAH, such as DMBA.
(2) The reason we have postulated that one-electron oxidation plays an important role in the activation of PAH derives from certain common characteristics of the radical cation chemistry of the most potent carcinogenic PAH.
(3) It is suggested that the atmosphere of Athens favours the formation of secondary direct-acting mutagens due to the oxidation and nitration of PAH by ozone and nitrogen oxides, which are more abundant in the late spring months.
(4) The cytosol binding activity apparently decreased but reincubation of the cytosol with the radioactive ligand completely restored "4S" PAH-BP activity.
(5) PAH levels have progressively decreased in the last few decades, most probably due to the introduction of anti-smoke regulations and the decrease of coal burning for heating.
(6) The haplotype associations, relative frequencies, and distributions of five prevalent PAH mutations (R158Q, R261Q, IVS10nt546, R408W, and IVS12n1) were established in a comprehensive European sample population and subsequently were examined to determine the potential roles of several genetic mechanisms in explaining the present distribution of the major PKU alleles.
(7) The stimulation was followed by short-term hyperpolarization of primary afferents (PAH; 1-5 min) and by depression of dorsal root potentials (DPRs) which had a similar time course to the delta [K]e, and were not blocked by naloxone.
(8) An isolated rat kidney preparation was used, and the uptake of UB by renal tissue, the UB appearance in the urine, and the secretion of PAH were analyzed throughout the perfusion.
(9) The analytical method for PAH determination is based on filter extraction, two-dimensional thin-layer chromatography and fluorescence spectrometry; lead is measured by atomic absorption.
(10) Thus, the substantially invasive procedure of ureteral catheterization is not required to ascertain left and right kidney PAH clearance in patients already at risk from renal disease.
(11) Uroporphyrin, heptacarboxylic acid porphyrin, and coproporphyrin are the major porphyrins to accumulate in response to PAHs (for example, 3,3',4,4'-TCBP in chick embryo liver cell culture).
(12) We have also found useful for the determination of acceptable concentration levels for the noncarcinogenic PAHs an analogous methodology based on the relative toxicities of the noncarcinogenic PAHs.
(13) The carcinogenic potency not only of PAH-containing extracts but also of the whole exhausts has often been estimated from their benzo[a]pyrene (BP) content.
(14) Deposition fluxes of Pb, Cd, Cu and a range of 11 PAH compounds have been determined at distances of 3.8-220 m from the M6 motorway in northwest England over a period of 21 months.
(15) Sucrose-gradient analysis of BeP binding activity indicated that BeP bound with high affinity to the 4S PAH-binding protein, but not to the Ah receptor.
(16) The air was sampled daily by glass fiber's filters; a ponderal determination of total particulate was made; PAH was dosed by gas-chromatography and by mass spectrometry, metals was determined by atomic absorption spectrometry.
(17) Both the occupational and in particular the therapeutic exposure to coal tar resulted in clear increases in urinary levels of PAH metabolites as compared to unexposed subjects.
(18) Simultaneous imposition of the pH gradient (outward OH- gradient) and inward Na+ gradient stimulated PAH uptake significantly over that with an Na+ gradient alone.
(19) Using PAH as a marker for the maximal extractable perfusion flow, 1-naphthol could be regarded as a high-extraction compound even at high perfusion flow rates.
(20) Experiments with basolateral membrane vesicles prepared from rat kidney cortex were performed to study the mechanism by which p-aminohippuric acid (PAH) is taken up across the contraluminal membrane and is concentrated in proximal tubule cells.
Pax
Definition:
(n.) The kiss of peace; also, the embrace in the sanctuary now substituted for it at High Mass in Roman Catholic churches.
(n.) A tablet or board, on which is a representation of Christ, of the Virgin Mary, or of some saint and which, in the Mass, was kissed by the priest and then by the people, in mediaeval times; an osculatory. It is still used in communities, confraternities, etc.
Example Sentences:
(1) By radioactive in situ hybridization (ISH) using a fragment from the murine Pax-1 paired box that is almost identical to the respective sequences from the cognate human gene HuP48 and fluorescence in situ hybridization (FISH) using a complete mouse Pax-1 cDNA, we have assigned the human homologue of murine Pax-1, the PAX1 locus, to chromosome 20p.
(2) Concurrent research has recently characterized Sp2H, a radiation induced mutation at the splotch (Sp) locus, and found alterations in the murine paired box gene, Pax-3, in homozygous Sp2H DNA.
(3) The chromosomal location of all novel Pax genes and of Pax-3 and Pax-7 has been determined and reveals that they are not clustered.
(4) Here we describe the paired boxes of three novel Pax genes, Pax-4, Pax-5, and Pax-6.
(5) Zebrafish pax[b](pax[zf-b]) is a member of the Pax gene family that is expressed in the presumptive posterior midbrain from the end of gastrulation and, at later stages, in other localized regions of the developing embryo.
(6) However, there are some differences in Pax-2 expression between the two species.
(7) These results support the Pax-6 homologue as a strong candidate for the AN2 gene.
(8) The chromosomal location and the mutation in the paired box of un mice in conjunction with Pax 1 gene expression in wild-type mice implicate a causative role of Pax 1 in generation of the vertebral column.
(9) Pax-3 encodes a 479 amino acid protein with an Mr of 56 kd containing both a paired domain and a paired-type homeodomain.
(10) The murine paired-box-containing gene 5, Pax-5, is highly homologous to two other Pax genes, Pax-2 and Pax-8.
(11) The Pax-2 expression domain in the prospective brain of E8 mouse embryos has not been described previously.
(12) Here we describe a zebrafish (Brachydanio rerio) paired box-containing clone, pax[zf-a], which is clearly distinct from reported vertebrate Pax genes.
(13) pax-6 expression appears during processes when cell-to-cell signalling is thought to be important, for example during induction of the eye and regionalization of the spinal cord and brain, suggesting that it may be one component mediating the response to inductive interactions.
(14) We describe the isolation and characterization of Pax-3, a novel murine paired box gene expressed exclusively during embryogenesis.
(15) Among the genes thought to be involved in patterning the nervous system are a family of developmentally regulated paired box-containing (Pax) genes.
(16) However, normal v-Myb- and c-Myb-expressing CNR cells all express the pax-QNR gene, a newly described paired and homeobox-containing gene specifically expressed in the neuroretina.
(17) The brain, the optic stalk, the auditory vesicle, the pronephros, and single cells in the spinal cord and the hindbrain express Pax-2 in both species.
(18) Mutations in Pax-6 have been described previously in Small eye, the proposed mouse model for aniridia.
(19) To date five murine paired box-containing genes (Pax genes) have been described and one, Pax-1, has been associated with the developmental mutant phenotype undulated.
(20) However, a region of homology to the N-terminal half of paired-type homeoboxes is detected C-terminal to the pax[zf-b] paired domain.