(n.) Punishment suffered or denounced; suffering or evil inflicted as a punishment for crime, or connected with the commission of a crime; penalty.
(n.) Any uneasy sensation in animal bodies, from slight uneasiness to extreme distress or torture, proceeding from a derangement of functions, disease, or injury by violence; bodily distress; bodily suffering; an ache; a smart.
(n.) Specifically, the throes or travail of childbirth.
(n.) To inflict suffering upon as a penalty; to punish.
(n.) To put to bodily uneasiness or anguish; to afflict with uneasy sensations of any degree of intensity; to torment; to torture; as, his dinner or his wound pained him; his stomach pained him.
(n.) To render uneasy in mind; to disquiet; to distress; to grieve; as a child's faults pain his parents.
Example Sentences:
(1) Experience of pain is modified by intern and extern influences, and it can appear very multiformly in the chronicity.
(2) All subjects completed the Coping Strategies Questionnaire, which measures the use and perceived effectiveness of a variety of cognitive and behavioral coping strategies in controlling and decreasing pain.
(3) Although solely nociresponsive neurons are clearly likely to fill a role in the processing and signalling of pain in the conscious central nervous system, the way in which such useful specificity could be conveyed by multireceptive neurons is difficult to appreciate.
(4) Sixteen patients were operated on for lumbar pain and pain radiating into the sciatic nerve distribution.
(5) Needle acupuncture did, however, increase the pain threshold compared with the initial value (alpha = 0.1%).
(6) Pain is not reported in the removal area, the clinical examinations show identical findings on both patellar tendons, X-ray and ultrasound evaluations do not demonstrate any change in patellar position.
(7) For assessment of clinical status, investigators must rely on the use of standardized instruments for patient self-reporting of fatigue, mood disturbance, functional status, sleep disorder, global well-being, and pain.
(8) However, as the plan unravels, Professor Marcus's team turn on one another, with painfully (if painfully funny) results.
(9) During the chronic phase, pain was assessed using visual analogue scales at 8 AM and 4 PM daily.
(10) Symptoms, particularly colicky abdominal pain, improved during the period of chelation therapy.
(11) Cook, who has postbox-red hair and a painful-looking piercing in his lower lip, was now on stage in discussion with four fellow YouTubers, all in their early 20s.
(12) The main clinical symptom was pain, usually sciatica, while neurological symptoms were less common than they are in adults.
(13) The study revealed that hypophysectomy and ventricular injection of AVP dose dependently raised pain threshold and these effects were inhibited by naloxone.
(14) Anxious mood and other symptoms of anxiety were commonly seen in patients with chronic low back pain.
(15) During these delays, medical staff attempt to manage these often complex and painful conditions with ad hoc and temporizing measures,” write the doctors.
(16) In this study, a potassium nitrate-polycarboxylate cement was used as a liner and was found clinically to tend to preserve pulpal vitality and significantly eliminate or decrease postoperative pain.
(17) The successful treatment of the painful neuroma remains an elusive surgical goal.
(18) Univariate and multivariate analyses indicated previous LBP or back pain in another location of the spine were strongly associated with LBP during the study year.
(19) Our previous study demonstrated that acupuncture increased pain threshold of the body, especially in the inflammatory area.
(20) The triad of epigastric pain unrelieved by antacids, bilious vomiting, and weight loss, particularly after a gastric operation should make one suspect this syndrome.
Tolerance
Definition:
(n.) The power or capacity of enduring; the act of enduring; endurance.
(n.) The endurance of the presence or actions of objectionable persons, or of the expression of offensive opinions; toleration.
(n.) The power possessed or acquired by some persons of bearing doses of medicine which in ordinary cases would prove injurious or fatal.
Example Sentences:
(1) within 12 h of birth followed by similar injections every day for 10 consecutive days and then every second day for a further 8 weeks, with mycoplasma broth medium (tolerogen), to induce immune tolerance.
(2) No differences between the two substances were observed with respect to side effects and general tolerability.
(3) This treatment is usually well tolerated but not devoid of systemic effects.
(4) Well tolerated from the clinical and laboratory points of view, it proved remarkably effective.
(5) To estimate the age of onset of these differences, and to assess their relationship to abdominal and gluteal adipocyte size, we measured adiposity, adipocyte size, and glucose and insulin concentrations during a glucose tolerance test in lean (less than 20% body fat), prepubertal children from each race.
(6) Although temazepam was effective for maintaining sleep with short-term use, there was rapid development of tolerance for this effect with intermediate-term use.
(7) testosterone, fentanyl, nicotine) may ultimately be administered in this way, important questions pertaining to pharmacology (tolerance), toxicity (irritation, sensitisation) and dose sufficiency (penetration enhancement) remain.
(8) There were no biochemical or haematological abnormalities caused by prazosin but on continued therapy 16 patients developed tolerance to its effect.
(9) Characerization of further parameters such as relative susceptibility to tolerance induction and relative degree of specificity was not possible with the use of KLH as the antigen.
(10) Because of these different direct and indirect actions, a sudden cessation of sinus node activity or sudden AV block may result in the diseased heart in a prolonged and even fatal cardiac standstill, especially if the tolerance to ischemia of other organs (notably the brain) is decreased.
(11) Efficacy and tolerability of perorally administered desmopressin were evaluated in 12 adult patients suffering from central diabetes insipidus.
(12) This suggests that both blood transfusion and allograft are required for IL2 suppression and that this suppression may be related to the heart tolerance.
(13) At present, ACE inhibitors are preferred because they are usually better tolerated than conventional vasodilators and are clinically more effective.
(14) Changes in pain tolerance after administration of differently labelled placebos were studied by measuring the reaction time after a cold stimulus.
(15) TK1 showed the most restricted substrate specificity but tolerated 3'-modifications of the sugar ring and some 5-substitutions of the pyrimidine ring.
(16) Provided that adequate reflection is given and the appropriate moment chosen, it is well tolerated and provides all the necessary information.
(17) After large bowel removal, there was impaired glucose tolerance and attenuated plasma insulin secretion.
(18) Cardiac pump function is not affected, even in patients with ventricular dysfunction or heart failure, in whom chronic oral administration of the drug is well tolerated.
(19) These agents have been well-tolerated and generally produce a high incidence of sustained improvements in neutrophil counts and marrow morphology, although hemoglobin and platelet counts have generally not been altered.
(20) The above treatment is tolerated well and no serious side effects have been observed.