(a.) Full of pain; causing uneasiness or distress, either physical or mental; afflictive; disquieting; distressing.
(a.) Requiring labor or toil; difficult; executed with laborious effort; as a painful service; a painful march.
(a.) Painstaking; careful; industrious.
Example Sentences:
(1) Experience of pain is modified by intern and extern influences, and it can appear very multiformly in the chronicity.
(2) All subjects completed the Coping Strategies Questionnaire, which measures the use and perceived effectiveness of a variety of cognitive and behavioral coping strategies in controlling and decreasing pain.
(3) Although solely nociresponsive neurons are clearly likely to fill a role in the processing and signalling of pain in the conscious central nervous system, the way in which such useful specificity could be conveyed by multireceptive neurons is difficult to appreciate.
(4) Sixteen patients were operated on for lumbar pain and pain radiating into the sciatic nerve distribution.
(5) Needle acupuncture did, however, increase the pain threshold compared with the initial value (alpha = 0.1%).
(6) Pain is not reported in the removal area, the clinical examinations show identical findings on both patellar tendons, X-ray and ultrasound evaluations do not demonstrate any change in patellar position.
(7) For assessment of clinical status, investigators must rely on the use of standardized instruments for patient self-reporting of fatigue, mood disturbance, functional status, sleep disorder, global well-being, and pain.
(8) However, as the plan unravels, Professor Marcus's team turn on one another, with painfully (if painfully funny) results.
(9) During the chronic phase, pain was assessed using visual analogue scales at 8 AM and 4 PM daily.
(10) Symptoms, particularly colicky abdominal pain, improved during the period of chelation therapy.
(11) Cook, who has postbox-red hair and a painful-looking piercing in his lower lip, was now on stage in discussion with four fellow YouTubers, all in their early 20s.
(12) The main clinical symptom was pain, usually sciatica, while neurological symptoms were less common than they are in adults.
(13) The study revealed that hypophysectomy and ventricular injection of AVP dose dependently raised pain threshold and these effects were inhibited by naloxone.
(14) Anxious mood and other symptoms of anxiety were commonly seen in patients with chronic low back pain.
(15) During these delays, medical staff attempt to manage these often complex and painful conditions with ad hoc and temporizing measures,” write the doctors.
(16) In this study, a potassium nitrate-polycarboxylate cement was used as a liner and was found clinically to tend to preserve pulpal vitality and significantly eliminate or decrease postoperative pain.
(17) The successful treatment of the painful neuroma remains an elusive surgical goal.
(18) Univariate and multivariate analyses indicated previous LBP or back pain in another location of the spine were strongly associated with LBP during the study year.
(19) Our previous study demonstrated that acupuncture increased pain threshold of the body, especially in the inflammatory area.
(20) The triad of epigastric pain unrelieved by antacids, bilious vomiting, and weight loss, particularly after a gastric operation should make one suspect this syndrome.
Poignant
Definition:
(a.) Pricking; piercing; sharp; pungent.
(a.) Fig.: Pointed; keen; satirical.
Example Sentences:
(1) Totò was a legend in the Vesuvian city – a comedian of genius; poignant, mysterious.
(2) Fleeting though it may have been (he jetted off to New York this morning and is due in Toronto on Saturday), there was a poignant reason for his appearance: he was here to play a tribute set to Frankie Knuckles, the Godfather of house and one of Morales's closest friends, who died suddenly in March.
(3) One of the most poignant exchanges came when Tony was asked by @ juliangratton to sum up the last seven years of his life.
(4) The exercise yard is adorned with poignant children's paintings in response to school trips here.
(5) This double bind may be particularly poignant for grandparents in single mother families.
(6) This addition was particularly poignant as Andrew Jackson’s legacy includes the decision to sign the Indian Removal Act of 1830 , which gave the federal government power to expel Native American tribes from their land.
(7) This poignant letter, addressing Recep Tayyip Erdogan and written by one of the protesters in Istanbul's historic Taksim Square , was widely circulated on Turkey's social media.
(8) Treasure Island gives us an intense sense of place, and a poignant coming-of-age story full of moral ambiguity.
(9) Their songs ranged from the almost unbearably poignant ("Hand in Glove") to the frankly vulnerable ("How Soon is Now").
(10) The image of the France midfielder walking, head bowed, past the World Cup trophy is one of the more poignant in football history.
(11) The second series of BBC1’s hit drama Happy Valley ended on Tuesday night , bowing out in a wondrous blaze of confrontation, perceptive resolution and poignant revelation.
(12) Ed Miliband said: "This is a tragic and poignant reminder of the sacrifices made by our armed forces in serving our country with bravery and distinction."
(13) But the American author, already the recipient of the Man Booker International prize, the Pulitzer and the National Book award , said it was "particularly poignant for me to have gotten news of the award only a few weeks after the death of Carlos Fuentes, who received the award in 1994".
(14) A picture sits on each one of the chairs, decorated by poignant letters, orange flowers and gifts.
(15) Or perhaps we could focus on the relationship of Leia and Solo, now married, and there could be a heart-rendingly poignant study of their elderly existence together, rather like Michael Haneke's Amour , but set in space.
(16) Dern, all windblown white hair and stubble, is often entirely silent and withdrawn, and all the more compelling and poignant for that.
(17) On the basis of this limited but poignant experience, we propose an outline of steps in management to help others avoid similar problems.
(18) Yet the narratives in Benefits Street have a human and poignant quality, often presenting decent and compassionate people disenfranchised by an unfair society.
(19) Sandy Nairne, director of the NPG, said: "The Van Dyck self-portrait is a poignant portrait of great significance.
(20) It was poignant, afterwards, to hear Martínez try to put the human element into some perspective.