(a.) Affecting a whole people or a number of countries; everywhere epidemic.
(n.) A pandemic disease.
Example Sentences:
(1) The west Africa Ebola epidemic “Few global events match epidemics and pandemics in potential to disrupt human security and inflict loss of life and economic and social damage,” he said.
(2) The human immunodeficiency virus (HIV) has resulted in a worldwide pandemic of infection.
(3) The cholera-pandemic raging in South and Middle America and endemic cholera in other countries call for measures of health protection of the local population, but particularly with respect to the young, old, pregnant and immunocompromised citizens of countries importing food from the areas where the disease has struck.
(4) The seventh pandemic of cholera is still continuing (92 countries have so far been affected), and other organisms related to V. cholerae O1 are being reported increasingly frequently as the cause of diarrhoeal outbreaks as well as endemic diarrhoea.Recent research has considerably increased our understanding of how cholera is transmitted, the mechanisms by which V. cholera O1 produces disease, and the functioning of the local intestinal immune response by which individuals can be protected from infection.
(5) It is argued that prior to the present AIDS pandemic the efficiency of the rev receptor was enhanced by an ancestral recombination event.
(6) This study provides arguments that (1) strains of biotypes cholerae and El Tor are different clones, (2) a cholera pandemic is not a single world-wide epidemic (due to a single clone) but rather a simultaneous occurrence of several epidemics (several clones involved), and (3) epidemic waves of biotype El Tor could be due to the emergence of new clones.
(7) Two hypotheses are advanced for the range of hemagglutinin (HA) subtypes of viruses that can cause pandemics (1) circle or cycle limited to H1, H2, and H3 subtypes, thereby implying that a virus of the H2 subtype will cause the next pandemic; and (2) spiral, by which any one of the 14 HA subtypes recorded to date may be involved.
(8) This sequence is conserved in representative viruses from each of the major pandemics.
(9) The effect of the AIDS pandemic on the sexual behavior of the general population has not been clearly established.
(10) Mathematical modeling of the AIDS pandemic has been limited by the difficulty of satisfactorily representing the marked behavioral heterogeneity that characterizes the various populations at risk.
(11) Introductory comments are made regarding the seriousness of AIDS as a global pandemic, its initial identification and description, and the various patterns of epidemic spread observed throughout the world.
(12) The impact of the AIDS-pandemic on the social and economic structures will grow to very large dimensions in some countries.
(13) HIV is now a worldwide pandemic, affecting some ten million adults and one million children--the overwhelming majority from sub-Saharan Africa.
(14) (iv) The different virus lineages are predominantly host specific, but there are periodic exchanges of influenza virus genes or whole viruses between species, giving rise to pandemics of disease in humans, lower animals, and birds.
(15) Understanding of the nature and pathogenic mechanisms of the oral microbiota may lead to control of this pandemic infection.
(16) Only a limited number of A-subtypes of influenza virus so far caused disease in human subjects, pigs and horses; this occurred in more or less defined areas which occasionally showed epidemic aggravations, becoming apparent as rapidly spreading epidemics or otherwise in even the form of pandemics.
(17) This gap between discovery and disclosure allowed the Sony rootkit to become a global pandemic that infected hundreds of thousands of US military and government networks.
(18) The major antigenic changes in influenza A virus that occur at 10-year intervals reduce the effectiveness of existing vaccines and pose a problem for the control of pandemics by vaccination.
(19) These findings underline the importance of pigs as potential reservoirs for future human pandemics by the continued isolation (in Asia) of H3N2 and Hsw1N1 influenza viruses.
(20) Because prostitutes are viewed as a major source of a variety of sexually transmitted diseases (STDs), many researchers have studied their role in spreading the AIDS pandemic.
Systemic
Definition:
(a.) Of or relating to a system; common to a system; as, the systemic circulation of the blood.
(a.) Of or pertaining to the general system, or the body as a whole; as, systemic death, in distinction from local death; systemic circulation, in distinction from pulmonic circulation; systemic diseases.
Example Sentences:
(1) This particular variant of rheumatoid arthritis (RA) is characterized by the presence of subcutaneous rheumatoid nodules, scanty or absent systemic manifestations and a clinically benign course.
(2) These factors might account for the lower systemic bioavailability of these compounds.
(3) The most actively proliferating region of the excurrent duct system is zone 3 of the epididymis, whereas the least active region is the ductuli efferentes.
(4) In 49 cases undergoing systemic lymphadenectomy 32 were found to have glandular involvement, of which both aortic and pelvic nodes were positive in 17 cases (53.1%), aortic nodes positive but pelvic negative in six (18.8%), and pelvic nodes positive but aortic negative in nine (28.1%).
(5) An automated continuous flow sample cleanup system intended for rapid screening of foods for pesticide residues in fresh and processed vegetables has been developed.
(6) Spectral analysis of spontaneous heart rate fluctuations, a powerful noninvasive tool for quantifying autonomic nervous system activity, was assessed in Xenopus Laevis, intact or spinalized, at different temperatures and by use of pharmacological tools.
(7) Herpesviruses such as EBV, HSV, and human herpes virus-6 (HHV-6) have a marked tropism for cells of the immune system and therefore infection by these viruses may result in alterations of immune functions, leading at times to a state of immunosuppression.
(8) It is concluded that during exposure to simulated microgravity early signs of osteoporosis occur in the tibial spongiosa and that changes in the spongy matter of tubular bones and vertebrae are similar and systemic.
(9) The telencephalic proliferative response has been studied in adult newts after lesion on the central nervous system.
(10) In dogs, cibenzoline given i.v., had no effects on the slow response systems, probably because of sympathetic nervous system intervention since the class 4 effects of cibenzoline appeared after beta-adrenoceptor blockade.
(11) The various evocational changes appear to form sets of interconnected systems and this complex network seems to embody some plasticity since it has been possible to suppress experimentally some of the most universal evocational events or alter their temporal order without impairing evocation itself.
(12) The Cavitron Ultrasonic Surgical Aspirator (CUSA) is a dissecting system that removes tissue by vibration, irrigation and suction; fluid and particulate matter from tumors are aspirated and subsquently deposited in a canister.
(13) In cardiac tissue the adenylate system is not a good indicator of the energy state of the mitochondrion, even when the concentrations of AMP and free cytosolic ADP are calculated from the adenylate kinase and creatine kinase equilibria.
(14) These results suggest the presence of a new antigen-antibody system for another human type C retrovirus related antigens(s) and a participation of retrovirus in autoimmune diseases.
(15) The combined analysis of pathogenesis and genetics associated with the salmonella virulence plasmids may identify new systems of bacterial virulence and the genetic basis for this virulence.
(16) We determined whether serological investigations can assist to distinguish between chronic idiopathic autoimmune thrombocytopenia (cAITP) and immune-mediated thrombocytopenia in patients at risk to develop systemic lupus erythematosus (SLE); 82 patients were seen in this institution for the evaluation of immune thrombocytopenia.
(17) The results demonstrated that K2PtCl4 was bound to a greater degree than CDDP in this system with 3-5 and 1-2 platinum atoms respectively, bound per transferrin molecule.
(18) IgE-mediated acute systemic reactions to penicillin continue to be an important clinical problem.
(19) The PSB dioxygenase system displayed a narrow substrate range: none of 18 sulphonated or non-sulphonated analogues of PSB showed significant substrate-dependent O2 uptake.
(20) Although solely nociresponsive neurons are clearly likely to fill a role in the processing and signalling of pain in the conscious central nervous system, the way in which such useful specificity could be conveyed by multireceptive neurons is difficult to appreciate.