(a.) Having the highest rank or jurisdiction; superior to all others; chief; supreme; preeminent; as, a paramount duty.
(n.) The highest or chief.
Example Sentences:
(1) The results of our phenotypic and functional testing of unmodified GIC (no enzyme treatment, no additional culture with or without interleukin 2), show that T cells, especially OKT8+ cells, are of paramount importance in the mechanism of this type of acute irreversible rejection of human renal allografts (i.e., to the point of allograft rupture), but other potential effector mechanisms are also present in situ.
(2) mechanisms of quality control, including extensive programs of orientation, inservice, and utilization review, are paramount in achievement of success.
(3) In the Labour party over the past two decades, the leader has become paramount, directing not just his own staff, but Labour headquarters.
(4) Urinalysis, a simple front-line test, is of paramount importance in the evaluation and management of the patient with urinary tract infection.
(5) Since the primary diagnosis of this condition is almost invariably based on cytologic observations, the diagnostic criteria are of paramount importance.
(6) José Manuel Barroso, the re-elected commission chief, stressed that rather than being seen as president of Europe, or Europe's paramount leader, the new post should be confined to the European council, which groups national governments from the member states.
(7) They emphasize that life-time diagnosis of pericardial mesothelioma is of paramount importance because rational chemotherapy permits prolongation of the patient's survival.
(8) The paramount feature revealed by immunohistological double marker analyses was the intimate association of myoid cells (antigen producing) with interdigitating reticulum cells (potentially antigen presenting cells), both of which were surrounded by T3+ lymphocytes in thymus medulla.
(9) The latter method is suitable for routine use in renography when accuracy is not of paramount importance.
(10) These preliminary data confirm the paramount importance of cellular immunity in controlling neoplasias.
(11) The use of zinc nitrate is favored if toxicological considerations are paramount, but ninhydrin development has to be carefully controlled if optimal results are to be obtained.
(12) The functional end result is of paramount importance.
(13) The symptoms of anaemia and indigestion appear to be paramount in making an early diagnosis, and negative barium meal studies should not be accepted when these two symptoms are present.
(14) These results might be of paramount significance in developing the detection method for HCV infection and in preparing HCV vaccine.
(15) Correct diagnosis and understanding of its pathogenesis is paramount in order to apply definite surgical treatment.
(16) Regardless of the technique utilized it remains paramount that the surgeon plan the initial procedure with great care as each failure results in diminished blood supply to the graft bed and makes subsequent procedures less likely to succeed.
(17) The work presented here gives a description, analysis and discussion of the effect of organic loading which is a paramount parameter of the performance of RBC's.
(18) The intended application is to assist in treatment selection during phase II trials, especially with rapid responses and when the disease involved is serious enough that design-motivating ethical considerations become paramount.
(19) Although the precise mechanism of thrombosis is incompletely known, the recognition of this type of dementia is of paramount importance as it is a potentially treatable condition.
(20) An understanding of the pathophysiology of anaphylaxis, the most serious of the allergic disorders, is paramount for its diagnosis.
Predominant
Definition:
(a.) Having the ascendency over others; superior in strength, influence, or authority; prevailing; as, a predominant color; predominant excellence.
Example Sentences:
(1) A group I subset (six animals), for which predominant cultivable microbiota was described, had a mean GI of 2.4.
(2) These results indicate that astrocytes possess bradykinin receptors and that these are predominantly of the B2 subtype.
(3) Exudative inflammatory processes predominate in the ulcer floor.
(4) The secondary leukemia that occurred in these patients could be distinguished from the secondary leukemia that occurs after treatment with alkylating agents by the following: a shorter latency period; a predominance of monocytic or myelomonocytic features; and frequent cytogenetic abnormalities involving 11q23.
(5) In hypophysectomized rats the activity of alanine aminotransferase was increased, but its normal zonation (predominance in the periportal zone) was preserved.
(6) Anaerobes, in particular Bacteroides spp., are the predominant bacteria present in mixed intra-abdominal infections, yet their critical importance in the pathogenicity of these infections is not clearly defined.
(7) I hope this movement will continue and spread for it has within itself the power to stand up to fascism, be victorious in the face of extremism and say no to oppressive political powers everywhere.” Appearing via videolink from Tehran, and joined by London mayor Sadiq Khan and Palme d’Or winner Mike Leigh, Farhadi said: “We are all citizens of the world and I will endeavour to protect and spread this unity.” The London screening of The Salesman on Sunday evening wasintended to be a show of unity and strength against Trump’s travel ban, which attempted to block arrivals in the US from seven predominantly Muslim countries: Iran, Iraq, Libya, Sudan, Somalia, Syria and Yemen.
(8) Analysis of conjugated discharges ACHs showed that they appeared predominantly periodically (87% of cases).
(9) Alcohol abuse remains the predominant cause of chronic liver disease in the Western world.
(10) Immunogold electron microscopy demonstrated that outer dense fibres were the predominant immunoreactive site.
(11) Saturated acyl residues predominated in lysolecithin and unsaturated ones in acids released by hydrolysis of egg lecithin.
(12) The axons of A5, RPoOl and RaD neurons exhibit no lateral predominance in their spinal projections.
(13) Of the three patients with a pure or predominantly endometrioid pattern treated with diethylstilbestrol, two had a marked clinical response.
(14) The mRNA data of the developing gut correspond with previous protein data, which showed that the shorter Mr 210,000 polypeptide predominates during earlier developmental stages and the larger Mr 260,000 polypeptide appears later in the embryonic gut (Aufderheide, E., and P. Ekblom.
(15) Neisseria meningitidis group B serotype 2 strain M986 contains two predominant outer membrane proteins, with apparent molecular weights of 41,000 (protein b) and 28,000 (protein e).
(16) Preliminary rhythmic somatic stimulation has a predominantly facilitating effect on EPs appearing in response to tonal stimuli in the areas A1, S2, S1.
(17) Following injections of HRP into the apex of the heart, the sinoatrial (SA) nodal region and the ventral wall of the right ventricle, we observed that HRP-labeled sympathetic neurons were localized predominantly in the right stellate ganglia, and to a lesser extent, in the right superior and middle cervical ganglia, and left stellate ganglia.
(18) Ultrastructual analysis indicated that the majority of the microtubules assembled predominantly from the pericentriolar material but also onto the centrioles.
(19) The organisms were predominantly associated with host deposits of erythrocytes, phagocytes, platelets, and fibrinous-appearing material, which collectively appeared on the valve surface in response to trauma.
(20) These animals spent a much greater portion of their SWS in the lighter SWS I, as compared to the control group which showed a predominance of the deeper SWS II.