(a.) Having the highest rank or jurisdiction; superior to all others; chief; supreme; preeminent; as, a paramount duty.
(n.) The highest or chief.
Example Sentences:
(1) The results of our phenotypic and functional testing of unmodified GIC (no enzyme treatment, no additional culture with or without interleukin 2), show that T cells, especially OKT8+ cells, are of paramount importance in the mechanism of this type of acute irreversible rejection of human renal allografts (i.e., to the point of allograft rupture), but other potential effector mechanisms are also present in situ.
(2) mechanisms of quality control, including extensive programs of orientation, inservice, and utilization review, are paramount in achievement of success.
(3) In the Labour party over the past two decades, the leader has become paramount, directing not just his own staff, but Labour headquarters.
(4) Urinalysis, a simple front-line test, is of paramount importance in the evaluation and management of the patient with urinary tract infection.
(5) Since the primary diagnosis of this condition is almost invariably based on cytologic observations, the diagnostic criteria are of paramount importance.
(7) They emphasize that life-time diagnosis of pericardial mesothelioma is of paramount importance because rational chemotherapy permits prolongation of the patient's survival.
(8) The paramount feature revealed by immunohistological double marker analyses was the intimate association of myoid cells (antigen producing) with interdigitating reticulum cells (potentially antigen presenting cells), both of which were surrounded by T3+ lymphocytes in thymus medulla.
(9) The latter method is suitable for routine use in renography when accuracy is not of paramount importance.
(10) These preliminary data confirm the paramount importance of cellular immunity in controlling neoplasias.
(11) The use of zinc nitrate is favored if toxicological considerations are paramount, but ninhydrin development has to be carefully controlled if optimal results are to be obtained.
(12) The functional end result is of paramount importance.
(13) The symptoms of anaemia and indigestion appear to be paramount in making an early diagnosis, and negative barium meal studies should not be accepted when these two symptoms are present.
(14) These results might be of paramount significance in developing the detection method for HCV infection and in preparing HCV vaccine.
(15) Correct diagnosis and understanding of its pathogenesis is paramount in order to apply definite surgical treatment.
(16) Regardless of the technique utilized it remains paramount that the surgeon plan the initial procedure with great care as each failure results in diminished blood supply to the graft bed and makes subsequent procedures less likely to succeed.
(17) The work presented here gives a description, analysis and discussion of the effect of organic loading which is a paramount parameter of the performance of RBC's.
(18) The intended application is to assist in treatment selection during phase II trials, especially with rapid responses and when the disease involved is serious enough that design-motivating ethical considerations become paramount.
(19) Although the precise mechanism of thrombosis is incompletely known, the recognition of this type of dementia is of paramount importance as it is a potentially treatable condition.
(20) An understanding of the pathophysiology of anaphylaxis, the most serious of the allergic disorders, is paramount for its diagnosis.
Preeminent
Definition:
(a.) Eminent above others; prominent among those who are eminent; superior in excellence; surpassing, or taking precedence of, others; rarely, surpassing others in evil, or in bad qualities; as, preeminent in guilt.
Example Sentences:
(1) The difficulty in reconciling these results with the preeminent role assigned to the hypothalamus in the organization of predatory aggressive behavior was considered.
(2) 1) Neurophysiological abnormalities in patients with renal failure are being investigated because a) it is the nervous system which preeminently produces the phenomena of clinical uremia that dialysis affects and b) objective quantitative measures of such functions are generally lacking and are needed to provide objective evidence for adequacy of dialysis and other treatment measures in uremic patients.
(3) Recent trends in psychiatry, such as shorter hospitalization and the renewed preeminence of biological treatments, are changing the practice of psychiatric nursing.
(4) In extreme anticipatory condensation--what I do propose, from my own reflections, is the preeminent importance of an archaic characterological core in depressive illness.
(5) It is certain to continue to be the preeminent factor in control of the disease in others.
(6) The fourth premise is expressed succinctly in the 11 principles outlined in the 1983 AAMC monograph "Preserving America's Preeminence in Medical Research," which places important responsibilities for the collective success of the U.S. research program on all of the various components of society.
(7) Visual impairments have a preeminent place in gerontology because they are a constant feature of the aging process.
(8) Consequently, these indicators should never be viewed in isolation or be given preeminence over clinical judgment.
(9) They point out the obvious preeminence of arterial disease on venous ones, and discuss about the panel of therapy association usable.
(10) Among the many technical issues dealt with in this symposium, two clinical problems are preeminent--how is schizophrenia defined and what is meant by outcome?
(11) The ABR threshold evoked by an unmasked click stimulus is, therefore, preeminently useful as a high-frequency point of a two-point audiogram.
(12) Patients with Type 2 (non-insulin-dependent) diabetes mellitus and a strong family history of the disease may represent a sub-group where genetic factors play a preeminent role in transmission of the disease.
(13) Prostate specific antigen (PSA) has replaced prostatic acid phosphatase as the preeminent clinical tumor marker in the management of patients with prostate cancer.
(14) The authors describe a periodicity of one to two decades in which one of the schools achieves preeminence over the others, consolidates its position in medical education and with the community at large, comes under fire for failing to provide solutions to the problems of the mentally ill, and finally experiences a decline of its influence and prestige.
(15) William Ellergy Briggs was California's preeminent ophthalmologist for more than fifty years.
(16) Assuming pK'RH = PH beta max, the calculated fractional dissociation of RH, alpha RH, was constant between 0 and 30 degrees C. The nature of RH is discussed in relation with Reeves's hypothesis concerning the preeminence of protein imidazole groups in the regulation of extra- and intracellular pH.
(17) The 1980s has been a critical decade for the management of acute myocardial infarction (MI) because of the concentration in a very short time span of innovative results produced by a new generation of trials, in which thrombolysis has been the preeminent topic.
(18) This aspect was once considered as a secondary feature in respect to the severity of prognosis quod vitam of the subjects affected with cancer, while now, with a significant increase of survival, it is preeminent that there be the possibility to offer these patients an acceptable quality of life under both physical and social profiles.
(19) Once dependent on the educational and professional resources of other countries, by the end of World War II the United States was recognized as one of the preeminent centers of the world for medical science and teaching.
(20) Its preeminent effects are increased pain threshold and alpha-adrenergic blockade.