(1) Comparison of wild type and the mutant parD promoter sequences indicated that three short repeats are likely involved in the negative regulation of this promoter.
(2) In contrast to CcdB, the Kid protein of the ParD system induces RecA-dependent cleavage of the cI repressor of bacteriophage lambda very inefficiently or not at all.
(3) The rate of admissions to psychiatric hospitals of patients with primary alcohol-related diagnoses (PARD) has increased from 1971 to 1983 and they now account for 19.7% of all admissions.
(4) Since the parDE operon requires the presence of the parCBA operon for efficient stabilization under certain growth conditions, the potential role of multimer resolution in plasmid stabilization was tested by substituting the ColE1 cer site for the parCBA operon.
(5) The system, which we have called ParD, maps inside the 1.45-kb PstI-EcoRI fragment that is adjacent to the origin of replication of the plasmid.
(6) And then I read another article recently that I am coming and watch over your shoulder Pards.
(7) Both of these promoters are repressed by their own gene products in the same manner in all three bacteria tested, with ParA functioning as the primary repressor of p-parCBA and ParD functioning as the repressor of p-parD.
(8) The ParD protein appears to bind to one inverted repeat sequence, located between the -35 and -10 boxes of p-parD.
(9) In vitro mutagenesis with hydroxylamine of a ParD- miniderivative of R1, pAB174, yielded mutants that were less stable in the cell than pAB174.
(10) The deletion analysis further allowed a redefinition of the minimal functional region as 790 bp in length, consisting of the parD gene (243 bp) and its promoter as well as sequences downstream of parD.
(11) When I speak with Pards tomorrow he may see some other position that he wants to look better of or get a better player for that area.
(12) Determination of the 5' ends of ParD transcripts, revealed that the genes coding for these proteins are transcribed from a single promoter.
(13) While the cer site did function to resolve plasmid multimers, it was not sufficient to restore stabilization activity to the parDE operon under growth conditions that require the parCBA operon for plasmid stability.
(14) The phenotype of a recently-described mutant (OV6), conditionally defective in chromosome partitioning and septal positioning, was originally thought to be due to a new gene (parD) mapping at 88.4 min.
(15) Transcriptional fusions were used to show that parA, parB, and parC are combined in an operon, while parD constitutes a separate transcription unit.
(16) The stability determined by the systems ParD of plasmid R1 and Ccd of plasmid F is due to the concerted action of two proteins, a cytotoxin and an antagonist of this function.
(17) In this paper we report that CcdA and Kis proteins, the antagonists of the Ccd and ParD systems respectively, share significant sequence homologies at both ends.
(18) The proteins P10 and P12 have been shown to be gene products of a new stability system, ParD, of plasmid R1.
(19) We have now shown that, in addition to the parD mutation, OV6 carries a gyrAam mutation and that this mutation is probably responsible for the gross phenotype of the mutant.
(20) Two divergently arranged promoters located in the intercistronic region between parC and parD mediate transcription of these genes.
Pare
Definition:
(v. t.) To cut off, or shave off, the superficial substance or extremities of; as, to pare an apple; to pare a horse's hoof.
(v. t.) To remove; to separate; to cut or shave, as the skin, ring, or outside part, from anything; -- followed by off or away; as; to pare off the ring of fruit; to pare away redundancies.
(v. t.) Fig.: To diminish the bulk of; to reduce; to lessen.
Example Sentences:
(1) A study was made of the dynamics of the changes occurring in the curve of restoration of the test response amplitude in the thalamo-cortical fibers to the pared stimulation of the medial lemniscus with various actions on the somatosensory ared.
(2) I loved that attention to detail, everything pared down to the bone."
(3) However, the announcements made at the tail-end of the Labour administrations have been pared back or delayed as ministers attempt to balance public spending cuts with infrastructure improvements.
(4) In recent weeks, repeated efforts had been made to pare down and modify the legislation to placate the rebellious conservatives in the party.
(5) Canada and Australia feel the squeeze in wake of Chinese economic slowdown Read more Japan’s Nikkei brushed aside an unexpected drop in the country’s industrial output to close up 2.7%, paring losses for the quarter to 14.1%, its deepest since 2010.
(6) It has not passed audit since 1994 and makes Britain's Ministry of Defence seem a haven of cheese-paring efficiency .
(7) These radical reactions should be considered when using human nail parings to estimate accidental exposure to ionizing radiation.
(8) The fact markets pared back this bounce soon after the announcement may in some respects reflect growing market concern that central banks are delving into a tit-for-tat currency devaluation war,” said Angus Nicholson at the online trading firm IG in Melbourne.
(9) Her first BBC series since her drug revelations and split from Charles Saatchi, it promises a “new pared-down approach to cooking and eating”.
(10) The NHS has pared back so much over the last 20 years, it now carries almost no flab.
(11) The cure rate was 84% for sheep that were only footbathed, 72% for those foot pared and footbathed, 72% for those foot pared, footbathed and given penicillin, and 88% for those vaccinated and footbathed.
(12) Yes, we all understood that he was the metaphorical Naked Chef because of the pared down bish-bash-bosh style of cookery, but he might as well genuinely have got his kit off for all the difference it made.
(13) The work and pensions secretary believes that restricting child benefit, which could save £1bn a year, could help Osborne achieve his cuts rather than “cheese paring” all benefits.
(14) The assumption that problem-oriented records help teach critical thinking was tested by co-paring clinical recordings and case study data for a group of beginning nursing students who were taught problem-oriented charting with a group who were taught traditional charting.
(15) It was assumed that the pared-down track programme compared with Beijing, stripped of most of the meaningful endurance events, might work to Great Britain's disadvantage, but the opposite appears to be the case.
(16) It is not possible that doing nothing will be cheaper than doing something; that budget cuts, pared-down services and postcode lotteries will yield anything but higher costs and more human misery.
(17) However, when the upstream sequence was pared down to base number -118, the regulatory response to O2, H2, and Ni levels was negated.
(18) Thus, it is the presence of noisy, incoherent dot motion, rather than brief lifetimes, that causes such poor performance on the stimulus of Newsome and Pare (1988).
(19) But while the Bank has only slightly pared back its growth forecasts since its last Inflation Report in August, the same can’t be said of inflation.
(20) The director of such high-risk projects as the National Theatre's runaway hit War Horse and its more recent smash, The Curious Incident Of the Dog in the Night-Time , as well as the dark, pared-down Port , which recently opened at the Lyttelton, she has never knowingly opted for a theatrical safe bet.