(1) Immunofluorescence and immunoelectronmicroscopy experiments demonstrated that while tight junctions demarcate PAS-O distribution in confluent cultures, apical polarity could be established at low culture densities when cells could not form tight junctions with neighboring cells.
(2) On dissected mucosa stained by the PAS-alcian blue whole-mount method the density and distribution of goblet cells in various parts of the middle ear was determined in 13 children, ranging in age from 9 days to 14 years.
(3) The results showed immunostaining to function equally well on frozen and routine sections, and to be superior to Alcian Blue and PAS with regard to morphological detail.
(4) The Personality Assessment System (PAS) is derived from certain subtest scores on any Wechsler test by rather simple calculations.
(5) Acidic mucus containing goblet cells have been revealed using Alcian blue staining when added to the PAS stained cells in conditions that have previously been shown to have reduced goblet cell population when assessed by PAS-haematoxylin staining.
(6) In neutrophilous peripheral blood leucocytes of healthy and leucotic cattle the PAS reaction attained the values of ++ to +++.
(7) In the untreated sections only glycogen revealed strong PAS reaction, most mucosubstances reacted weakly or not at all.
(8) After a three-month period of rigorous training, two PAs were assigned to the ICU.
(9) Vacuolar or intraluminal binding of peanut lectin was found to be more sensitive than PAS reaction for detecting early secretory activity.
(10) Paraphilias (PAs) and non-paraphilic sexual addictions (NPSAs) may be behaviors that share a common perturbation of central serotonin neuroregulation as a component of their pathophysiology.
(11) In addition, we should carefully interpret the muscle histochemistry, because histochemical stains including PAS might be fairly normal in the defects with second step glycolytic pathway.
(12) The PAS hyperchromaticity of basement membrane material and pericyte loss occurred throughout the retinal vasculature, while while the microaneurysms and complex lesions were limited to the capillaries of the central and paracentral retina.
(13) However, pulmonary arterial pressure was the same as controls at both day 8 and day 14 in MCTP-treated rats made moderately thrombocytopenic by cotreatment with PAS.
(14) These bodies were PAS-positive and stained with MT, and They had electron-dense complex structures.
(15) Thus, in man, tear fibrinolytic activity may depend primarily on a release of PAs from conjunctival tissue.
(16) Also in some areas, the cytoplasmic processes at the distal ends of the PAs invaded the predentin.
(17) The materials positive for the PAS and PTO reactions in alveolar septa are epithelial and endothelial basal laminas, which are nonargyrophilic.
(18) In some areas, the tumor shows a striking resemblance to Kaposi's sarcoma; criss-crossing fascicles of spindle cells are interspersed with narrow vascular spaces, but PAS-positive hyaline globules are absent.
(19) Within the PGE2-protected animals a significant increase was observed in the length of zones of the mucus-producing cells at the surface and in the foveolae (both PAS-positive and alcian-blue-positive cells).
(20) Serous granules were stained by toluidine blue, or by hematoxylin and eosin (H and E), but showed little or no reaction with periodic acid-Schiff (PAS) or Alcian blue.
Upas
Definition:
(n.) A tree (Antiaris toxicaria) of the Breadfruit family, common in the forests of Java and the neighboring islands. Its secretions are poisonous, and it has been fabulously reported that the atmosphere about it is deleterious. Called also bohun upas.
(n.) A virulent poison used in Java and the adjacent islands for poisoning arrows. One kind, upas antiar, is, derived from upas tree (Antiaris toxicaria). Upas tieute is prepared from a climbing plant (Strychnos Tieute).
Example Sentences:
(1) Binding of uPA to filters was blocked by a synthetic oligopeptide containing the known receptor binding region of native uPA.
(2) The synthesis of uPA as a precursor with reduced enzymatic activity as well as decreased affinity for inhibitors is likely to be a mechanism by which normal epidermis regulates plasminogen activation in vivo.
(3) We identified two human melanoma cell lines, MelJuso and MeWo, expressing uPA or tPA as shown at mRNA, protein, and enzyme activity level.
(4) The Jarman UPA score at electoral ward level is not related to psychiatric morbidity, and should not therefore be used for planning local service provision.
(5) Mutants of the pig kidney cell line, LLC-PK1, affected in cAMP metabolism, were examined for cAMP-dependent protein kinase (cAMP-PK) activity and for cAMP-mediated induction of urokinase-type plasminogen activator (uPA).
(6) Since in addition to fibronectin, that can be degraded by uPA or plasmin, chorioallantoic membrane connective tissue contains collagen, we examined the profile of collagenases secreted by the various cell lines in search for an activity that would coincide with the invasive phenotype.
(7) Rat alveolar epithelial cells produce large quantities of urokinase-type plasminogen activator (uPA) in vitro, and uPA expression is modulated in association with cellular differentiation and exposure to inflammatory mediators.
(8) Immunoreactive uPA was induced equally by IFN and TNF, but TNF generated higher levels of PAI-2.
(9) Thus, cathepsin B can substitute for plasmin in the proteolytic activation of pro-uPA to enzymatically active HMW-uPA.
(10) Plasmin formation, dependent on the urokinase-type plasminogen activator (uPA), is discussed in its biochemical, regulatory and physiological aspects and its involvement in cancer malignancy analysed.
(11) (iv) At high concentrations of sigma factor, only certain adenosine-containing dinucleoside monophosphates (ApU, CpA, UpA, and ApA) stimulate the reaction.
(12) The peptide hormone calcitonin induces the accumulation of urokinase-type plasminogen activator (uPA) mRNA in pig kidney LLC-PK1 cells.
(13) PA activity was also associated with the leading edges of migrating epithelium post-scrape and post-burn and was not inhibited by antibodies to either tPA or uPA but was inhibited by amiloride.
(14) However, the RNase A mutant containing residues 63-74 of angiogenin had greatly diminished catalytic activity against uridylyl-(3'----5')-adenosine (UpA), and slightly increased catalytic activity as an inhibitor of translation in vitro.
(15) Hence receptor-bound uPA will promote plasminogen activation and thus the dissolution of the tumor matrix and the basement membrane which is a prerequisite for invasion and metastasis.
(16) Treatment of A431 squamous carcinoma cells (SqCC) with epidermal growth factor (EGF) has previously been shown to result in an induction of the synthesis and extracellular accumulation of uPA and the plasminogen-dependent proteolysis of extracellular matrix (ECM).
(17) Enzymatic properties of phosphorylated urokinase plasminogen activator (P-uPA) (1) extracted from human carcinomatous cell line Detroit 562 cells were compared with those of non-phosphorylated uPA of urinary origin (nP-uPA).
(18) In all of 10 cases, staining for uPA in the normal colon tissue was confined to scattered fibroblastlike cells in the lamina propria.
(19) It is proposed that uPA:uPA-receptor interaction plays a direct role in physiological and pathological processes that require cell migration.
(20) High molecular weight uPA, either as the single-chain precursor or two-chain activated form, bound to the receptor; however, low molecular weight (33 kD) uPA, tPA, or epidermal growth factor did not compete for binding, demonstrating specificity.