What's the difference between pastille and spheroid?

Pastille


Definition:

  • (n.) A small cone or mass made of paste of gum, benzoin, cinnamon, and other aromatics, -- used for fumigating or scenting the air of a room.
  • (n.) An aromatic or medicated lozenge; a troche.
  • (n.) See Pastel, a crayon.

Example Sentences:

  • (1) Validation studies, to show that the method is precise, accurate and rectilinear, have been carried out on four linctus formulations and two pastille formulations.
  • (2) This parallel, double-blind, randomized, placebo-controlled study evaluated the acceptance and effectiveness of the nystatin pastille at two different dosages.
  • (3) A selective high-performance liquid chromatographic procedure has been developed for the determination of the major Ipecacuanha alkaloids, emetine and cephaeline, in a number of linctus and pastille preparations.
  • (4) The potential for enhanced drug delivery to the oropharynx suggests that nystatin pastilles may be useful in patients in whom poor compliance seems likely.
  • (5) I think the very first case on was a 14- or 15-year-old who'd taken, I think it was something like two packets of Fruit Pastilles and a can of Coke from a small store in the city centre.
  • (6) The flavored pastille was well accepted by the subjects and both dosages were shown to be effective in significantly reducing or eliminating the Candida organism during active therapy.
  • (7) Fifty consecutive patients with respiratory diseases who developed oropharyngeal candidiasis were assessed clinically and microbiologically before and after seven days' treatment with nystatin suspension or pastilles (a new formulation).
  • (8) Sample preparation is simple, involving either straight dilution for linctus formulations or simple dissolutions for pastilles.
  • (9) Pastilles and suspension were equally efficacious both clinically and microbiologically.
  • (10) Nystatin has been formulated in the form of a flavored pastille (troche) as an alternative to the oral suspension.
  • (11) Asked if he wants to be prime minister, he tends to throw up chaff, saying that he is more likely to be reincarnated as a doughnut or a Rowntree's Fruit Pastille or whatever takes his fancy.
  • (12) The qualitative and quantitative composition of microflora was studied in fruit and vegetable juices, pastilles and sauces of sublimation drying.

Spheroid


Definition:

  • (n.) A body or figure approaching to a sphere, but not perfectly spherical; esp., a solid generated by the revolution of an ellipse about one of its axes.

Example Sentences:

  • (1) Microelectrodes were used to measure the oxygen tension (PO2) profile within individual spheroids at different stages of growth.
  • (2) Aside from typical nuclear spheroids, irregularly shaped nuclei were frequently seen, associated with increased nuclear folds, transitional stages between nuclear folds and nuclear spheroids were also present.
  • (3) The nuclei in these typical onocytes appeared oval or spheroid.
  • (4) The tumor cells of these melanomas are characterized by spheroidal melanosomes and containing pheomelanins.
  • (5) This is a clinical, histopathological and electron microscopical study on the spheroidal degeneration of the cornea by means of 48 histologically verified cases.
  • (6) Our results show the feasibility of back-extrapolating multicellular tumour spheroid growth curves to obtain survival estimates that can be applied to establish sublethal damage repair capacity.
  • (7) HCG, E2 and P4 were secreted into the culture medium throughout the entire culture period, in proportion to spheroid size.
  • (8) In addition, it was observed that the higher resistance of the V79 spheroid cells than the monolayers to gamma-irradiation is not diminished in the pion peak, suggesting that the underlying phenomenon of intercellular communication influences cell survival even after high-LET irradiation.
  • (9) Under the 3-dimensional geometry of the spheroid system, there was, however, generally a more extensive ECM.
  • (10) The spheroids grew exponentially with a volume-doubling time of approximately 24 h up to a diameter of approximately 580 microns and then the growth rate tapered off, more for spheroids grown at the low than at the high oxygen tension.
  • (11) The cytotoxicity of doxorubicin (DX), 4'-O-methyl-DX (MET-DX), 4'-deoxy DX (DEO-DX), 4'-deoxy-4'-iodo-DX (IODO-DX), daunorubicin (DNR)and 4-demethoxy-DNR (DM-DNR) on LoVo cells cultured as a monolayer (in exponential and stationary phases of growth) and as spheroids, are evaluated following 1-h exposure to the drugs.
  • (12) Under conditions of severe hypoxia (< 0.01% O2), 2 h of pretreatment or 18 h of simultaneous treatment with SR 4233 did not significantly enhance the effectiveness of 131I-NR-LU-10 in spheroids.
  • (13) The reported prevalence and severity of primary spheroidal degeneration in Labrador and nothern Newfoundland is based on a survey of 929 patients.
  • (14) Apparently the latter represented conglomerates of adherent spheroid elements that resembled somewhat "large bodies" of L-forms.
  • (15) The results of immunotitration and immunodiffusion experiments and of the sodium dodecyl sulfate-polyacrylamide gel electrophoretic analysis of immunoprecipitates revealed: (i) a high degree of immunochemical identity of this enzyme only within the family Enterobacteriaceae; (ii) intermediate-to-weak cross-reaction with the phenylalanyl-tRNA ligases from Pseudomonadaceae, Rhodopseudomonas spheroides, and Bacillus stearothermophilus; (iii) no detectable cross-reaction (with the methods employed) with the enzymes from several gram-positive organisms, Euglena gracilis, and several fungi.
  • (16) Histological alterations included nerve fibre swelling and degeneration, occasional spheroids, astrocytic gliosis, increased macrophage activity and increased perivascular collagen.
  • (17) The photosynthetically-incompetent mutant V-2 of Rhodopseudomonas spheroides which is incapable of synthesising bacteriochlorophyll was grown aerobically under conditions of both high and low aeration.
  • (18) Transplanted spheroids continued to express the growth inhibitory activity.
  • (19) The outer-layer cells of spheroids and fed plateau monolayers peaked at a similar density; the majority of middle-layer cells banded close to unfed plateau and exponential hypoxic monolayers, while most inner-layer cells banded where fed or unfed plateau hypoxic monolayer peaked in density.
  • (20) Survival of spheroid and monolayer cells after hypertonic NaCl treatment was identical.