(a.) Specially or decisively characteristic of a disease; indicating with certainty a disease; as, a pathognomonic symptom.
Example Sentences:
(1) Focal biliary cirrhosis is the pathognomonic hepatic lesion and is present in 25-30% of CF patients, most of whom are asymptomatic.
(2) We have not discovered any specific EUS finding(s) that are pathognomonic for pancreatic cancer or chronic pancreatitis.
(3) In certain diseases, the morphologic alterations are characteristic and pathognomonic.
(4) More than a decade of study of regional cerebral blood flow (rCBF) has gradually shown a pathognomonic pattern of abnormalities, probably reflecting spreading cortical depression.
(5) The changes are distinctive and pathognomonic, but the effects of therapy (vitamin D) have not yet been ascertained.
(6) Because of the nonspecific nature of symptoms produced and absence of pathognomonic findings by physical examination or by routine laboratory testing, its recognition is difficult and its true incidence is unknown.
(7) Although there are no pathognomonic symptoms, signs, or radiological appearances of intracranial tuberculomas, a high index of suspicion should always be entertained during the investigation of non-European immigrants.
(8) Periodic acid-Schiff-positive, diastase resistant, intracytoplasmic crystals, pathognomonic for alveolar soft-part sarcoma, were present.
(9) The retinal lesions observed in primary hyperoxaluria appear to be pathognomonic for hyperoxalaemia.
(10) Importantly, although not pathognomonic, the high-resolution CT finding of centrilobular, peribronchiolar, indistinct nodules should suggest the diagnosis of chronic hypersensitivity pneumonitis.
(11) Although these splenic features are not pathognomonic for abscesses, they can be correlated with other incidental abdominal sonographic findings and the presenting clinical symptoms, can direct percutaneous needle punctures and can enable a prompt diagnosis.
(12) However, whether these changes are specific or pathognomonic to any disease(s) remains to be solved.
(13) A knowledge of the pathognomonic features may lead to early detection and treatment.
(14) Angiomyolipomas produce pathognomonic appearances on modern imaging methods and a tissue diagnosis is no longer required particularly when multiple tubers can be confidently diagnosed and if a CT brain scan shows periventricular calcifications.
(15) In Hellmer's original article and all cases subsequently reported, this appearance was described as being pathognomonic of intraperitoneal fluid.
(16) The fine morphology of hematoxylin bodies--structures which, by light microscopy, are considered to be pathognomonic for systemic lupus erythematosus--is described in renal glomeruli.
(17) Thus pancreatic calcifications, which are virtually pathognomonic for chronic pancreatitis, were found exclusively in the group with chronic nephropathy due to analgesic abuse.
(18) Gas patterns in the portal and umbilical vessels are unique and pathognomonic.
(19) Pathognomonic signs were pain behind the lateral femoral condyle on palpation and compression of the fabella and also on passive extension of the knee.
(20) These findings may be considered pathognomonic for enchondromatosis (Ollier's disease).
Rash
Definition:
(v. t.) To pull off or pluck violently.
(v. t.) To slash; to hack; to cut; to slice.
(n.) A fine eruption or efflorescence on the body, with little or no elevation.
(n.) An inferior kind of silk, or mixture of silk and worsted.
(superl.) Esp., overhasty in counsel or action; precipitate; resolving or entering on a project or measure without due deliberation and caution; opposed to prudent; said of persons; as, a rash statesman or commander.
(superl.) Uttered or undertaken with too much haste or too little reflection; as, rash words; rash measures.
(superl.) So dry as to fall out of the ear with handling, as corn.
(v. t.) To prepare with haste.
Example Sentences:
(1) The rash presented either as a pityriasis rosea-like picture which appeared about three to six months after the onset of treatment in patients taking low doses, or alternatively, as lichenoid plaques which appeared three to six months after commencement of medication in patients taking high doses.
(2) Two young patients presented with generalised lymphadenopathy, otorrhoea, otitis, and rash.
(3) --The frequency of common clinical manifestations (eg, headache, fever, and rash) and laboratory findings (eg, leukocyte and platelet counts and serum chemistry abnormalities) of patients with infectious diseases was tabulated.
(4) The cause of death was thought to be postoperative Graft Versus Host Disease with skin rash and pancytopenia.
(5) Adverse reactions associated with ticlopidine included neutropenia (severe in one patient) with no clinical complications, diarrhea, or rash.
(6) The presence of an erythematous skin rash and hemorrhagic complications in acute graft-versus-host disease (GVHD) suggest that the vasculature may be involved in the immunopathologic process.
(7) Hypersensitivity reactions, most commonly skin rashes or pruritus, affect about 1% of patients.
(8) The adverse effects were negligible--one patient had light urticarial rash and pruritus.
(9) In vitro invasion and in vivo metastasis assays were performed with a panel of MCF-7 cells transfected with isogenic constructs of mutated rasH genes.
(10) We describe a man who presented with Reiter's syndrome and a new prominent malar rash.
(11) A 71-year-old female showed a rash over the S2-4 dermatomes on the right side.
(12) Somebody rashly asked if he listened to the recently reprieved 6 Music – no – or even Radio 1, which he only caught, he said, when turning the dial between Radios 3 and 4.
(13) These indicators included temperature elevation, inability to be consoled, level of alertness, nuchal rigidity, bulging fontanel, decreased appetite, rash, referral, and febrile seizures.
(14) Extracardiac adverse effects of quinidine include potentially intolerable gastrointestinal effects and hypersensitivity reactions such as fever, rash, blood dyscrasias and hepatitis.
(15) The protective effects of FK565 against systemic infections with herpes simplex virus (HSV) and murine cytomegalovirus (MCMV), respiratory tract infection with influenza virus and zosteriform rash with HSV investigated in mice.
(16) These included petechial rash, hypertrichosis, acute renal failure, fluid retention and cardiac failure.
(17) These results suggest a frequent infection with HHV-6 only a few weeks after BMT and a close association between the infection with the virus and the development of skin rashes.
(18) Of these five, one came from a 'normal' control who had a positive anti-nuclear antibody (ANA), facial rash and diabetes, two were from patients with systemic lupus erythematosus (SLE) and two were from patients with mixed connective tissue disease (MCTD).
(19) The drug was withdrawn in 6 patients--lack of response in one, thrombocytopenia in one, urticaria in one, rash in one, and granulocytopenia in 2.
(20) Supplementation with zinc sulfate 220 mg per day via nasogastric tube resulted in disappearance of the rash with return of serum zinc to normal levels.