(n.) A line of ancestors; descent; lineage; genealogy; a register or record of a line of ancestors.
(n.) A record of the lineage or strain of an animal, as of a horse.
Example Sentences:
(1) Pedigree studies have suggested that there may be an inherited predisposition to many apparently nonfamilial colorectal cancers and a genetic model of tumorigenesis in common colorectal cancer has been proposed that includes the activation of dominantly acting oncogenes and the inactivation of growth suppressor genes.
(2) Several pedigrees have been reported in which defects of the insulin gene result in glucose intolerance or diabetes in affected members, but the role of insulin gene mutations in NIDDM is unknown.
(3) Another feature of TWINAN90 is the optional output of a pedigree file which can be read by the quantitative genetics package FISHER.
(4) ESD in conjunction with RB polymorphism would be useful in prenatal and presymptomatic diagnosis, as well as in carrier detection in informative pedigrees.
(5) This paper presents a FORTRAN IV subroutine to calculate inbreeding and kinship coefficients from pedigree information in a diploid population without self-fertilization.
(6) Histologic examination of one patient from each pedigree showed two characteristic findings in corneal epithelium; the previously designated "peculiar substance" in the cells, and the vacuolated homogeneous substance mostly within the cysts.
(7) While Elop has critics who say he did not fix Nokia or much of anything else in his long career in tech, others are likely to point to a pedigree that would also make him the favorite here.
(8) The pedigree analysis provided evidence of both a genetic effect (P less than 0.005) and an effect of increased dietary iron (P less than 0.005) on transferrin saturation and unsaturated iron-binding capacity.
(9) On the other hand, Sillence OI type I segregated with both COL1A1 (17 pedigrees) and COL1A2 (7 pedigrees).
(10) Using 166 pedigrees, reported in nine series available in the literature (including our own), we conclude that balanced insertion cannot entirely explain the familial data, even if we allow for a reduced viability of unbalanced gametes.
(11) To study the genetic influence on serum cholesterol levels and early coronary heart disease, 1,134 individuals were screened from 18 Utah pedigrees.
(12) An informative Dutch pedigree showed that two other linked polymorphic DNA markers, Pi227 and YN5.48, closely flank the FAP locus, one on either side.
(13) Discordant segregation between COL2A1 and the mutant locus was seen in pedigrees with multiple epiphyseal dysplasia, autosomal recessive spondyloepiphyseal dysplasia tarda, hypochondroplasia, pseudoachondroplasia, diaphyseal aclasis, and trichorhinophalangeal syndrome.
(14) Samples originated from eight schizophrenics and 27 relatives belonging to a large pedigree, thus ensuring biological homogeneity.
(15) We describe a codon 299 mutation in the glucokinase gene in a British pedigree with maturity-onset diabetes of the young (MODY) resulting in a substitution of glycine to arginine.
(16) We have studied five Italian pedigrees segregating schizophrenia using a map of four markers for the chromosomal region 5q11.2-13.3.
(17) Using three markers of chromosome 5, we have studied 28 additional French pedigrees.
(18) The phenotypically and often cytogenetically normal transmitting males in fragile X pedigrees are interpreted not as "nonpenetrant" transmitters of a fully formed fragile X but rather as transmitters of some or all of the factors necessary for TE insertion at Xq27.
(19) The problem has acquired practical importance because of the current international collaboration aimed at constructing a complete human linkage map of DNA markers through the study of three-generation pedigrees.
(20) Linkage analysis with four CMT1A pedigrees mapped the CMT1A gene with respect to two flanking markers (8B10-5 cM[LOD 5.2]-CMT1A-3.5 cM[LOD 5.3]-10E4).
Poodle
Definition:
(n.) A breed of dogs having curly hair, and often showing remarkable intelligence in the performance of tricks.
Example Sentences:
(1) In a 12-year-old poodle, tumor cells with the following abnormalities were found: trisomy 1, monosomy X and two marker chromosomes.
(2) Three breeds (beagle, boxer, and golden retriever) had a significantly greater risk for thyroid carcinoma than did all dogs combined, whereas miniature and toy poodles had a low risk.
(3) Talking last month on his late-night HBO show Last Week Tonight , Oliver ridiculed Gen Prayuth Chan-ocha's "dystopian nightmare" of a government, called Crown Prince Maha Vajiralongkorn a "buffoon" and an "idiot", and ridiculed a clip of a contentious home video of the prince and his semi-naked wife at a poolside birthday party for their pet poodle Foo Foo.
(4) Insulin-like growth factors (IGFs) I and II were decreased 71 and 44% respectively in miniature compared to standard size poodles.
(5) A case of chronic granulocytic leukemia was diagnosed in a ten year old miniature poodle and was observed for four and one half years.
(6) Its inaction over allegations of widespread phone hacking at the News of the World led it to being branded a "toothless poodle".
(7) Systemic lupus erythematosus with polymyositis and polyarthritis was diagnosed in a 7-year-old female Standard Poodle.
(8) Data is presented of the post-mortem macroscopic and microscopic examination of two Toy Poodles with multiple enchondromatosis (Ollier syndrome).
(9) But you can't dismiss the wealth tax and say at the same time that Clegg is a Tory poodle, although many will.
(10) At necropsy, a 15-year-old male Standard Poodle had a 6-cm diameter mass in the perianal region.
(11) The mean age was 7.0 years for all breeds, 5.1 years for the Cocker Spaniel, and 9.0 years for the Poodle breeds.
(12) Fluorescein angiographic findings in 7 carriers and 7 homozygotes of a recessively inherited disease, generalized progressive retinal atrophy of the poodle, are described in detail and comparisons with 24 healthy control poodles are presented.
(13) A three-year-old poodle showed changes in its behaviour, which were so marked as to induce the owner to inquire after the possible use of spectacles for her dog.
(14) Full-field electroretinograms (ERGs) were recorded between the ages of 4 and 34 months from 8 miniature French poodles with inherited progressive rod-cone degeneration (PRCD) and from 11 normal miniature poodles.
(15) They shouldn't be given the chance to turn it into a poodle once again.
(16) Miniature and Toy Poodles, Pomeranians, and Shetland Sheepdogs were identified as being at high risk for PDA.
(17) In the present study, the rod outer segments of young prcd affected miniature poodles and normal dogs have been compared with respect to the incorporation of intravitreally injected [3H]palmitic acid.
(18) Meanwhile the plush London offices of all his overlapping enterprises are right across from the US embassy in Grosvenor Square, as if to taunt critics who claim he is America's poodle.
(19) The cytological changes in these Poodle pups were notably different from those reported in earlier ultrastructural studies of canine inherited cerebellar degenerations.
(20) It was concluded that the condition had similarities to both congenital dyserythropoietic disorders and true megaloblastic conditions, but until further investigations are reported it might be wise to refer to it as "bone marrow dyscrasia" in poodles.