(n.) A line of ancestors; descent; lineage; genealogy; a register or record of a line of ancestors.
(n.) A record of the lineage or strain of an animal, as of a horse.
Example Sentences:
(1) Pedigree studies have suggested that there may be an inherited predisposition to many apparently nonfamilial colorectal cancers and a genetic model of tumorigenesis in common colorectal cancer has been proposed that includes the activation of dominantly acting oncogenes and the inactivation of growth suppressor genes.
(2) Several pedigrees have been reported in which defects of the insulin gene result in glucose intolerance or diabetes in affected members, but the role of insulin gene mutations in NIDDM is unknown.
(3) Another feature of TWINAN90 is the optional output of a pedigree file which can be read by the quantitative genetics package FISHER.
(4) ESD in conjunction with RB polymorphism would be useful in prenatal and presymptomatic diagnosis, as well as in carrier detection in informative pedigrees.
(5) This paper presents a FORTRAN IV subroutine to calculate inbreeding and kinship coefficients from pedigree information in a diploid population without self-fertilization.
(6) Histologic examination of one patient from each pedigree showed two characteristic findings in corneal epithelium; the previously designated "peculiar substance" in the cells, and the vacuolated homogeneous substance mostly within the cysts.
(7) While Elop has critics who say he did not fix Nokia or much of anything else in his long career in tech, others are likely to point to a pedigree that would also make him the favorite here.
(8) The pedigree analysis provided evidence of both a genetic effect (P less than 0.005) and an effect of increased dietary iron (P less than 0.005) on transferrin saturation and unsaturated iron-binding capacity.
(9) On the other hand, Sillence OI type I segregated with both COL1A1 (17 pedigrees) and COL1A2 (7 pedigrees).
(10) Using 166 pedigrees, reported in nine series available in the literature (including our own), we conclude that balanced insertion cannot entirely explain the familial data, even if we allow for a reduced viability of unbalanced gametes.
(11) To study the genetic influence on serum cholesterol levels and early coronary heart disease, 1,134 individuals were screened from 18 Utah pedigrees.
(12) An informative Dutch pedigree showed that two other linked polymorphic DNA markers, Pi227 and YN5.48, closely flank the FAP locus, one on either side.
(13) Discordant segregation between COL2A1 and the mutant locus was seen in pedigrees with multiple epiphyseal dysplasia, autosomal recessive spondyloepiphyseal dysplasia tarda, hypochondroplasia, pseudoachondroplasia, diaphyseal aclasis, and trichorhinophalangeal syndrome.
(14) Samples originated from eight schizophrenics and 27 relatives belonging to a large pedigree, thus ensuring biological homogeneity.
(15) We describe a codon 299 mutation in the glucokinase gene in a British pedigree with maturity-onset diabetes of the young (MODY) resulting in a substitution of glycine to arginine.
(16) We have studied five Italian pedigrees segregating schizophrenia using a map of four markers for the chromosomal region 5q11.2-13.3.
(17) Using three markers of chromosome 5, we have studied 28 additional French pedigrees.
(18) The phenotypically and often cytogenetically normal transmitting males in fragile X pedigrees are interpreted not as "nonpenetrant" transmitters of a fully formed fragile X but rather as transmitters of some or all of the factors necessary for TE insertion at Xq27.
(19) The problem has acquired practical importance because of the current international collaboration aimed at constructing a complete human linkage map of DNA markers through the study of three-generation pedigrees.
(20) Linkage analysis with four CMT1A pedigrees mapped the CMT1A gene with respect to two flanking markers (8B10-5 cM[LOD 5.2]-CMT1A-3.5 cM[LOD 5.3]-10E4).
Thoroughbred
Definition:
(a.) Bred from the best blood through a long line; pure-blooded; -- said of stock, as horses. Hence, having the characteristics of such breeding; mettlesome; courageous; of elegant form, or the like.
(n.) A thoroughbred animal, especially a horse.
Example Sentences:
(1) A 5-year-old Thoroughbred gelding was examined because of a small axillary wound sustained 5 days earlier and had resulted in extensive subcutaneous emphysema.
(2) Three basic techniques (and one modified technique) were developed, allowing successful excision of subepiglottic cysts in 10 horses (5 Standardbreds, 4 Thoroughbreds, and 1 Quarter Horse; mean age, 3.5 years) via peroral approach.
(3) It's so magnificent, like the swishing mane of a thoroughbred stallion … Too late, snip snip, off it comes.
(4) Plasma concentrations of estrogens, gestagens, cortisol (F), 13, 14-dihydro, 15-keto PGF2 alpha (PGFM) and pregnant mare serum gonadotropin (PMSG) in 10 Thoroughbred mares were measured for a 11-month pregnancy period.
(5) Thoroughbred horses were run at maximal O2 uptake on a high-speed treadmill until fatigued.
(6) Esophageal stenosis was diagnosed in a 7-day-old Thoroughbred foal referred for evaluation of bilateral milky nasal discharge.
(7) Thoroughbred horses have been bred exclusively for racing in England since Tudor times and thoroughbred horse racing is now practised in over 40 countries and involves more than half-a-million horses worldwide.
(8) No significant associations were detected between laryngeal hemiplegia and any ELA antigen in Thoroughbreds.
(9) The source of a previously described radiolucent crescent in the flexor cortex of the distal sesamoid (navicular) bone on the palmaro45 degrees proximal-palmarodistal oblique (Pa45 degrees Pr-PaDio) clinical radiographic projection was investigated in 48 forelimb navicular bones from 24 Thoroughbreds by use of high-detail radiography and x-ray computed tomography (CT).
(10) The difficulties that arise in filling out marking certificates for thoroughbreds are described.
(11) Her horse Barber’s Shop won the Tattersalls & RoR Thoroughbred Ridden Show.
(12) A Thoroughbred stallion with erectile dysfunction following paraphimosis was managed to allow consistent ejaculation.
(13) A project to determine if intraarticular corticosteroid therapy was deleterious to the racing Thoroughbred was carried out in the 1971, 1972, and 1973 racing seasons.
(14) Changes in concentration of a number of blood metabolites in 30 thoroughbred horses were recorded after an 1110 metre race.
(15) Gross post mortem examinations were performed on the lungs of 26 Thoroughbred horses of known exercise-induced pulmonary haemorrhage (EIPH) status.
(16) The gluteus medius of two killed Thoroughbred horses were sampled along the muscle and across the muscle at four different depths.
(17) The cumulative pregnancy rate after five services was 85% for Quarter-horse and 77% for Thoroughbred mares (P less than 0-05).
(18) Following either exercise or intravenous injection of adrenaline in six thoroughbreds, there was an increase in erythrocyte creatine content and a decrease in ATP concentration.
(19) Two foals aged 35 and 48 h from 2 Thoroughbred studs died several hours after developing clinical signs of depression, severe haemorrhagic diarrhoea and dehydration.
(20) Six Thoroughbred horses were biopsied the day before and within 30 minutes of completion of the speed and endurance test.