(n.) An erythematous affection of the skin, with severe constitutional and nervous symptoms, endemic in Northern Italy.
Example Sentences:
(1) On the basis of that work Joseph Goldberger developed a diet which produced a condition analogous to pellagra in dogs.
(2) Pellagra diagnosis was made on the basis of the typical clinical skin picture, and low urinary excretion of N'methylnicotinamide and N'methyl-2-pyridone-5-carboxamide (reduced by 70 and 80%, respectively, compared with controls).
(3) These results suggest that Zn interacts with niacin metabolism in alcoholic patients with pellagra through a probable mediation by vitamin B-6.
(4) D-xylose absorption tests and jejunal morphology have been shown to be unaltered in 12 African patients with pellagra when compared with normal values for Zambian Africa adults; that result is contrary to two previous investigations in India and Egypt respectively.
(5) 231 cases of pellagra among 8,000 consulting patients has been observed from May 1977 to June 1978 in the Dermatological Dispensary of the Hospital G.E.C.A.-Mines of Lumbumbashi (Zaire).
(6) Two types of pathologic state are unquestionably the concern of vitaminotherapy: More or less specific and intense vitamin deficiencies: Rickets, scurvy, beri beri, pellagra, vitamin deficiency related to alcohol consumption, polyneuritis, encephalopathy, malabsorption, mucoviscidosis, etc.
(7) Pellagra is a classical disease rarely seen in this country.
(8) Pellagra in the human is characterized by the clinical "three D's," namely, dermatitis, diarrhea, and dementia.
(9) Dermatoses with photosensitivity are divided into three groups: photo-aggravated dermatoses (solar herpes, lupus erythematosus), photosensitivity caused by protective system defect (xeroderma pigmentosum), and photosensitivity caused by metabolic defects (porphyrias, pellagra).
(10) His CNS lesions were composed of disseminated necrotic foci in the cerebral cortices with many Alzheimer type II astrocytes, pachymeningitis hemorrhagica interna, and lesions similar to pellagra and Wernicke encephalopathy.
(11) The nicotinamide nucleotide concentrations in the erythrocytes of subjects suffering from pellagra (pellagrins) were not lower than those in normal subjects, but the ability of erythrocytes to synthesize these nucleotides in vitro was significantly lower in pellagrins.
(12) In pellagra, symmetric keratotic areas on the face are always accompanied by lesions elsewhere on the body.
(13) It is concluded that pellagra per se does not alter intestinal structure or monosaccharide absorption.
(14) It is noted that some of the manifestations of prolonged sleep deprivation are similar to changes seen in pellagra.
(15) We evaluated the effects of SMS 201-995 in 14 such patients, 12 with diarrhea, 8 with flushing, 3 with wheezing, one with tricuspid valve incompetence, 6 with facial telangiectasia, 3 with a pellagra type dermatosis and one with myopathy.
(16) Tryp deficiency caused classical manifestations of pellagra although niacin intake was in excess of normal requirements.
(17) The first symptom of the disease was a serious and prolonged pellagra-like photodermatitis.
(18) Photosensitivity has also been associated with pellagra.
(19) The condition manifests as a pellagra-like skin rash within 8 weeks after birth, with signs of cerebellar ataxia and developmental retardation.
(20) A patient who was treated with isoniazid and who developed pellagra is presented.
Skin
Definition:
(n.) The external membranous integument of an animal.
(n.) The hide of an animal, separated from the body, whether green, dry, or tanned; especially, that of a small animal, as a calf, sheep, or goat.
(n.) A vessel made of skin, used for holding liquids. See Bottle, 1.
(n.) The bark or husk of a plant or fruit; the exterior coat of fruits and plants.
(n.) That part of a sail, when furled, which remains on the outside and covers the whole.
(n.) The covering, as of planking or iron plates, outside the framing, forming the sides and bottom of a vessel; the shell; also, a lining inside the framing.
(v. t.) To strip off the skin or hide of; to flay; to peel; as, to skin an animal.
(v. t.) To cover with skin, or as with skin; hence, to cover superficially.
(v. t.) To strip of money or property; to cheat.
(v. i.) To become covered with skin; as, a wound skins over.
(v. i.) To produce, in recitation, examination, etc., the work of another for one's own, or to use in such exercise cribs, memeoranda, etc., which are prohibited.
Example Sentences:
(1) The catheter must be meticulously fixed to the skin to avoid its movement.
(2) Elements in the skin therefore seemed to enhance nerve regeneration and function.
(3) This is a fascinating possibility for solving the skin shortage problem especially in burn cases.
(4) Blood flow decreased immediately after skin expansion in areas over the tissue expander on days 0 and 1 and returned to baseline levels within 24 hours.
(5) These findings suggest that clonidine transdermal disks lower blood pressure in hypertensive patients, but produce local skin lesions and general side effects.
(6) Currently, photodynamic therapy is under FDA-approved clinical investigational trials in the treatment of tumors of the skin, bronchus, esophagus, bladder, head and neck, and of gynecologic and ocular tumors.
(7) Immunofluorescent staining for HLA-DR showed dermal positivity in 12 of 13 involved- and 9 of 13 uninvolved-skin biopsy specimens from scleroderma patients, compared with only 1 of 10 controls.
(8) Blood flow was measured in leg and torso skin of conscious or anesthetized sheep by using 15-micron radioactive microspheres (Qm) and the 133Xe washout method (QXe).
(9) A similar interference colour appeared after incubating sections of rat skin with chymase.
(10) Peptides from this region bind to actin, act as mixed inhibitors of the actin-stimulated S1 Mg2(+)-ATPase, and influence the contractile force developed in skinned fibres, whereas peptides flanking this sequence are without effect in our test systems.
(11) This study was designed to examine the effect of the storage configuration of skin and the ratio of tissue-to-storage medium on the viability of skin stored under refrigeration.
(12) Somatostatin-like immunoreactivity has been found to occur in nerve terminals and fibres of the normal human skin using immunohistochemistry.
(13) We recommend analysing the urine for porphyrins in HIV-positive patients who have chronic photosensitivity of the skin.
(14) We investigated the incidence of skin cancer among patients who received high doses of PUVA to see whether such incidence increased.
(15) Attachment of the graft to the wound is similar with and without the addition of human basic fibroblast growth factor, a potent angiogenic agent, to the skin replacement before graft placement on wounds.
(16) In order to develop a sampling strategy and a method for analyzing the circadian body temperature pattern, we monitored estimates of the temperature in four ways using rectal, oral, axillary and deep body temperature from the skin surface every hour for 72 consecutive hours in 10 normal control subjects.
(17) It was shown that the antibiotic had low acute toxicity, did not cumulate and had no skin-irritating effect.
(18) Compliance during dehydration was 7.6 and 12.5% change in IFV per millimeter Hg fall in IFP (micropipettes) in skin and muscle, respectively, whereas compliance in subcutis based on perforated capsule pressure was 2.0% change in IFV per millimeter Hg.
(19) For the second propositus, a woman presenting with abdominal and psychiatric manifestations, the age of onset was 38 years; the acute attack had no recognizable cause; she had mild skin lesions and initially was incorrectly diagnosed as intermittent acute porphyria; the diagnosis of variegate porphyria was only established at the age of 50 years.
(20) 14 patients with painful neuroma, skin hyperesthesia or neuralgic rest pain were followed up (mean 20 months) after excision of skin and scar, neurolysis and coverage with pedicled or free flaps.