(v. t.) To enter into; to make way into the interior of; to effect an entrance into; to pierce; as, light penetrates darkness.
(v. t.) To affect profoundly through the senses or feelings; to touch with feeling; to make sensible; to move deeply; as, to penetrate one's heart with pity.
(v. t.) To pierce into by the mind; to arrive at the inner contents or meaning of, as of a mysterious or difficult subject; to comprehend; to understand.
(v. i.) To pass; to make way; to pierce. Also used figuratively.
Example Sentences:
(1) The penetration of (22)Na was not prevented by the presence of metabolic inhibitors or by 500 mm NaCl in the suspending medium.
(2) Content of cyclic nucleoside monophosphates was decreased in all the eye tissues in experimental toxico-allergic uveitis as well as penetration of cAMP into the fluid of anterior chamber of the eye.
(3) After four years of existence, many evaluations were able to show the qualities of this system regarding root canal penetration, cleaning and shaping.
(4) testosterone, fentanyl, nicotine) may ultimately be administered in this way, important questions pertaining to pharmacology (tolerance), toxicity (irritation, sensitisation) and dose sufficiency (penetration enhancement) remain.
(5) The automatic half of both the motor which advances the trepan as well as the second motor which rotates the trepan is triggered by the sudden change in electrical resistance between the trepan and the patient's internal body fluid, at the final stage of penetration.
(6) Thus, although ferric-enterochelin cannot penetrate the cell surface from outside, the complex that is formed within the envelope is transported normally into the cell.
(7) Major limitations of the conventional sperm penetration assay are the inability to assess several aspects of sperm function (zona binding and penetration) and the absence of human ovulatory products known to influence fertilization.
(8) The cercaria, microcercous in type, is liberated and actively penetrates a second terrestrial pulmonate where development to the free metacercarial stage takes place in the pericardial cavity.
(9) The incomplete penetrance of the neoplastic phenotype and the monoclonality of lymphoid tumors suggest that tumor formation in v-fps mice requires genetic or epigenetic events in addition to expression of the P130gag-fps protein-tyrosine kinase.
(10) All of these factors make morbidity and mortality associated with penetrating injuries low.
(11) The treatment led to decreased spinnbarkeit, arborization and sperum penetration in the cervical mucus.
(12) The penetration coefficient, determined by the surface tension, contact angle and viscosity, is a measure of the ability of a liquid to penetrate into a capillary space, such as interproximal regions, gingival pockets and pores.
(13) The rational surgical methods of treatment in 85 patients with suppurative hepatic echinococcosis penetrating into the abdomen cavity are presented.
(14) This apparent lack of centrosomal staining was not due to problems associated with penetration of the antibody probes, since staining adjacent to and within the centriolar cylinder was observed when phosphoprotein antigens recognized by the MPM-2 antibody were localized.
(15) Both types of oral cleft, cleft palate (CP) and cleft lip with or without CP (CLP), segregate in these families together with lower lip pits or fistulae in an autosomal dominant mode with high penetrance estimated to be K = .89 and .99 by different methods.
(16) Cefuzoname seems to be among the middle ranks of beta-lactam agents as far as penetration rate is concerned; however, when its potent antibacterial activity and broad spectrum are taken into account, the concentrations in CSF in patients with meningitis seem worth examining.
(17) The time of sperm penetration in the mouse eggs, however, was delayed for one-half to one hour when ejaculated sperm were used.
(18) Enzymatic lability does not, however, play as important a role as lipophilicity in the corneal and conjunctival penetration of cycloalkyl and aryl ester prodrugs.
(19) No infection threads were found to penetrate either root hairs or the nodule cells.
(20) Kinetic studies showed that significant inhibition of virus production occurred when the inhibitor was added to infected cultures up to 5 h after virus penetration.
Permeate
Definition:
(v. t.) To pass through the pores or interstices of; to penetrate and pass through without causing rupture or displacement; -- applied especially to fluids which pass through substances of loose texture; as, water permeates sand.
(v. t.) To enter and spread through; to pervade.
Example Sentences:
(1) In both instances the permeation rates of proteins can be better correlated to hydrodynamic radii than to molecular weights.
(2) In anaerobiosis, at 25 mM sulphanilic acid, or with addition of p-toluene sulphonic acid only one regression line is obtained for the permeation in both directions.
(3) The calpains were allowed to autolyze to completion, and the autolysis products were separated and were characterized by using gel permeation chromatography, calpastatin affinity chromatography, and sequence analysis.
(4) At 5 micrometer and 2.5 mM sulphanilic acid under aerobic conditions, the regression lines for the permeation from lumen to blood pass almost through the origin, while the regression lines for the permeation from blood to lumen intersect the ordinate at a positive Y-value.
(5) The breakthrough time and permeation rate at steady-state were calculated as described in the ASTM standard test method.
(6) Insulin-like growth factor-binding proteins (IGFBPs) in rat serum, lymph, amniotic fluid and cerebrospinal fluid (CSF), and in rat cell-conditioned media were characterized using a combination of gel-permeation chromatography, Western immunoblots and Western-ligand analysis.
(7) Glycerol permeation and thus its osmotic action may be less in the soleus than in other muscles.
(8) Previous histological evidence of the uptake of these particles and their absorption across the gastrointestinal tract and passage via the mesentery lymph supply and lymph nodes to the liver and spleen was confirmed by analysis of tissues for the presence of polystyrene by gel permeation chromatography.
(9) 10% NNDEMT doubled the amount of PFA in the skin, increased fourfold the amount permeated across the skin, and increased the flux fivefold.
(10) Various methodological weaknesses permeate the relevant literature.
(11) Time courses for in vivo total mucosal uptake exhibited linearity over a wide variety of absorption rates after correction for the permeation by intact metal-chelate complex.
(12) Gel permeation chromatography of the CIT-agarose eluates revealed one protein peak that coincided with PDE activity at an elution position of 135,000 daltons.
(13) Phospholipase A2 has been purified from the venom of Horned viper (Cerastes cerastes) by gel permeation chromatography followed by reverse-phase HPLC.
(14) The buccal absorption characteristics and physicochemical properties of the beta-adrenoceptor blocking agents propranolol and atenolol have been investigated to evaluate their permeation properties across biological lipid membranes.
(15) The permeation enhancer STDHF increases mucosal permeability and reduces the average molecular weight of the insulin species.
(16) I argue that the energy profile in the permeation pathway of most biological channels should vary relatively smoothly with only a few localized energy barriers or wells.
(17) Channels containing a variety of viable cells permeated the rice bodies.
(18) Estrogen receptor from human breast cancer tissue and from normal human uterus was isolated and characterized by a combination of physical separation methods including ammonium sulfate precipitation, gel permeation chromatography, isoelectric focusing and gel electrophoresis.
(19) However, we did not examine the mechanisms by which the apparent high permeation of sodium chloride occurs.
(20) For the skins without stratum corneum, the permeation rates and permeation amounts of l-NG and dl-NG were higher than those for the intact skin (P less than 0.01), but no significant difference was seen between l-NG and dl-NG.