(1) To study the role of the PENK gene in opioid related processes, an antisense sequence of PENK gene was subcloned into pSVL SV 40 late promoter expression vector and stably transfected into NG 108-15 cells, which contain opioid receptors.
(2) From steady-state kinetics half-life estimates of 9.6 h for PPenk mRNA and 14.7 h for Penk peptide were obtained.
(3) The Penk Combat Exposure scale did not separate the groups.
(4) "I was half expecting to see him on Songs of Praise," Penk added.
(5) Clinical observations and empirical evidence suggest that, among Vietnam combat veterans, Blacks are more maladjusted than Whites (e.g., Parsons, 1985; Penk et al., 1985).
(6) Penk, who now owns the Oldham-based local radio station 96.2 Revolution, said he was "appalled" at the "sheer scale of this unfair cross-promotion".
(7) "In these hard times it is difficult enough for the large, quasi-national commercial radio brands to compete with such unfair 'free' publicity," said Penk.
(8) The Penk Combat Intensity scale, which was correlated highly with the Keane scale, differentiated the PTSD-positive patients from both the normals and the PTSD-negative patients, but with less differentiating power (omega 2'S = .07 and .08).
(9) Facebook Twitter Pinterest The former Capital and Virgin Radio DJ Steve Penk has written to the BBC Trust to complain about the "excessive" and "gratuitous" cross-promotion of Chris Evans's new Radio 2 breakfast show on television.
(10) An increase in PENK mRNA levels has been also observed in cultures treated with 8-Br-cAMP, phorbol 12-myristate-13-acetate (TPA), or dexamethasone.
(11) Thus, activation of Penk gene expression upon neurotransmitter challenge is suggested to be due to an enhanced transcriptional activity of the gene mediated by de novo synthesized protein (-like) factors.
(12) We suggest that both the increased PENK message and the unchanged levels of free Met-enkephalin may be the result of compensatory mechanisms induced by translational inhibition by antisense, although the underlying processes remain to be determined.
(13) Penk was also critical of what he called the "placement" of Evans on BBC TV shows including Friday Night with Jonathan Ross, the One Show and the Andrew Marr Show.
(14) Unilateral adrenal denervation resulted in a rapid decrease in PPenk mRNA levels of 54% after 2 days, and by 11 days 90% of Penk mRNA had disappeared.
(15) Penk claimed the Evans trail broke the BBC Trust's own policy on cross-promotion.
(16) However, incubation of the cultures with the opioid agonist etorphine or the antagonist naltrexone did not alter PENK gene expression, suggesting that there is not feedback control of opioids on PENK biosynthesis in these cells.
(17) In this study we identified the potential sites of synthesis by localizing the mRNA coding for PENK in the rat pituitary gland using in situ hybridization histochemistry.
(18) Depolarization with potassium chloride (KCl) or veratridine increases the expression of PENK mRNA in a time-dependent fashion, with a maximal increase of sixfold.
(19) The proenkephalin A (PENK) gene codes for several opioid peptides, including Met-enkephalin, an endogenous ligand of opioid receptors.
(20) After an initial lag phase (with no major alterations) Penk mRNA increased markedly between 6 and 12 h followed by a slower, steady increase up to 48 h. The nicotinic receptor antagonist tubocurarine (4 x 10(-7) M) and the Ca2+ channel blocker D600 (10(-5) M) prevent the subsequent rise of Penk mRNA levels after challenge with nicotine, when given within the lag phase (0-6 h), suggesting the need of continuous receptor occupation and Ca2+ entry for induction of gene expression.
Pink
Definition:
(n.) A vessel with a very narrow stern; -- called also pinky.
(v. i.) To wink; to blink.
(a.) Half-shut; winking.
(v. t.) To pierce with small holes; to cut the edge of, as cloth or paper, in small scallops or angles.
(v. t.) To stab; to pierce as with a sword.
(v. t.) To choose; to cull; to pick out.
(n.) A stab.
(v. t.) A name given to several plants of the caryophyllaceous genus Dianthus, and to their flowers, which are sometimes very fragrant and often double in cultivated varieties. The species are mostly perennial herbs, with opposite linear leaves, and handsome five-petaled flowers with a tubular calyx.
(v. t.) A color resulting from the combination of a pure vivid red with more or less white; -- so called from the common color of the flower.
(v. t.) Anything supremely excellent; the embodiment or perfection of something.
(v. t.) The European minnow; -- so called from the color of its abdomen in summer.
(a.) Resembling the garden pink in color; of the color called pink (see 6th Pink, 2); as, a pink dress; pink ribbons.
Example Sentences:
(1) Vertical gratings are tinged with green and horizontal gratings with pink.
(2) Today, she wears an elegant salmon-pink blouse with white trousers and a long, pale pink coat.
(3) 7 male and 39 female undergraduates were alternately assigned to rooms painted red or Baker-Miller Pink.
(4) The first-floor lounge is decorated in plush deep pink, with a mix of contemporary and neoclassical decor, and an antique dining table and chandelier.
(5) The animals were exposed for 120 h to continuous pink noise at the intensities 80, 90 and 100 dB SPL.
(6) In this paper, previous literature on the subject is surveyed, and an experimental approach under standardized conditions to allow analysis of possible causes and biological mechanisms of the pink-teeth phenomenon in rats is described.
(7) Pink Monday said it was precisely the reaction it had hoped for.
(8) Positive specimens produce a faint pink deposit which is better visualised by silver enhancement which gives an intense black colour.
(9) The reason fashion magazines have been excited over the M&S coat is because various high-end designers all made pink coats this season.
(10) On other days, she dresses head to toe in bright pink.
(11) Other designs included short ruffle cocktail dresses with velvet parkas slung over the shoulder; blazers made of stringed pearly pink; and gold beading and a lace catsuit.
(12) Results obtained with a high pass filtered pink noise at a 106, 109 and 113 dB SPL on 37-40 week foetuses are given to illustrate this dependency.
(13) Approximately 30% of the C. neoformans strains produced large amounts of the pink (purple after 6 days) pigment in the absence of light whereas 70% of the Cryptococcus neoformans strains, as well as C. laurentii, C. albidus, C. diffluens, and C. albicans also produced the pink pigment with light being required for significant early production (2--6 days).
(14) Quality Street toffee penny yellow is the new pink Breaking news!
(15) The country’s supreme court ruled that Imelda Marcos illegally acquired the items, including diamond-studded tiaras and an extremely rare 25-carat pink diamond.
(16) On the opposite side there are obviously a few people who are full of a lot of hatred.” Jake Johnstone, who was was wearing the pink triangle of the 1980s Act Up movement, said: “Obviously we had the Paris attacks and everyone was shocked by it, but because Orlando was an attack on the LGBT community it feels very personal and a lot of people feel deeply affected by it.
(17) Now Alex Salmond, the SNP’s once and future king has been enjoying fish, chips and pink champagne with the editor of the New Statesman, Jason Cowley .
(18) They claim 13 Labour candidates received visits from Harriet Harman’s “pink bus” but did not declare this in their local returns, with the cost instead included in the national return; that the Lib Dems used an election battlebus to transport activists to constituencies which was not included in the candidates’ returns; and that the SNP leader, Nicola Sturgeon, “used a helicopter to campaign for SNP candidates in 12 target constituencies – at a cost of £35,000”.
(19) Grace Coddington, Dame Helen Mirren, Laura Mvula, and Karen Elson, in the pink duster coat that proved so popular for M&S.
(20) A group of young men and women calling themselves the Salopards (Bastards) and wearing pink dungarees "to show you can be against gay marriage without being homophobic", was also there to "defend the family".