(n.) An aromatic herb (Mentha Pulegium) of Europe; also, a North American plant (Hedeoma pulegioides) resembling it in flavor.
Example Sentences:
(1) As the major constituent of pennyroyal oil, PUL has been linked to the deaths of several young women over the past several years.
(2) A dog was treated for fleas with the application of pennyroyal oil obtained by the owner at a health food store.
(3) Intraperitoneal injection of R-(+)-pulegone (pulegone), the main constituent of pennyroyal oil, to ddY mice caused extensive liver injury as characterized by an increase in serum glutamic pyruvic transaminase (GPT) activity and centrilobular necrosis of hepatocytes.
(4) Other plants used are osha, chuchupate-lovage; ponso or tanse-tansy; poleo-spearmint or pennyroyal mint; amolillo-wild licorice; dormilon-tall cone flower; malva; and, lanten-plantain.
(5) Pulegone, a monoterpene that protects source plants against predators, is a hepatotoxic constituent of the folklore abortifacient pennyroyal oil.
(6) At necropsy, pennyroyal oil was determined to be the cause of death.
(7) The hepatotoxic monoterpene pulegone is a major constituent of the herbal abortifacient pennyroyal oil.
(8) (R)-(+)-Pulegone, the major monoterpene component of the abortifacient mint oil, pennyroyal oil, is metabolized by hepatic microsomal monooxygenases of the mouse to a hepatotoxin.
(9) The day's top singles were vinyl editions of David Bowie's Rock 'N' Roll Suicide, Oasis's Supersonic, Nirvana's Pennyroyal Tea, Bruce Springsteen's new American Beauty EP and One Direction's glammed-up Midnight Memories.
Tansy
Definition:
(n.) Any plant of the composite genus Tanacetum. The common tansy (T. vulgare) has finely divided leaves, a strong aromatic odor, and a very bitter taste. It is used for medicinal and culinary purposes.
(n.) A dish common in the seventeenth century, made of eggs, sugar, rose water, cream, and the juice of herbs, baked with butter in a shallow dish.
Example Sentences:
(1) The poisonous principles in tansy ragwort are pyrrolizidine alkaloids, which cause gradual alteration and necrosis of liver cells with replacement by fibrous tissue.
(2) The geranyl and linalyl precursors were shown to be mutually competitive substrates (inhibitors) of the relevant cyclization enzymes isolated from Salvia officinalis (sage) and Tanacetum vulgare (tansy) by the mixed substrate analysis method, demonstrating that isomerization and cyclization take place at the same active site.
(3) In control rats, most fecal vitamin A was excreted in the first 24 h post-dosing, while in tansy ragwort-fed animals, the excretion was delayed, suggesting a possible effect of PA on gut motility.
(4) The effect of feeding a diet containing 5% tansy ragwort (TR) (Senecio jacobaea), a poisonous plant containing pyrrolizidine alkaloids (PA), on the blood and liver levels of copper, zinc, iron and vitamin A in broiler chicks was examined.
(5) Calves and cows (n = 45) were fed daily doses of dried prebud tansy ragwort (Senecio jacobaea) derived from a single plant collection made in Tillamook, Oregon.
(6) In group 1, 4 calves were continuously fed dried tansy ragwort mixed in a pelleted feed at a 5% concentration by dry weight until terminal liver disease developed.
(7) The hepatotoxic alkaloids known to occur in tansy ragwort (Senecio jacobaea L.) are also present in honey produced from the nectar of this species.
(8) It is thus apparent that the disease can be confused clinically with many others, and tansy ragwort poisoning should be considered in animals exhibiting ascites, diarrhea and rectal prolapse.
(9) Recurrent photosensitization of cattle in Montana has been blamed on Descurainia pinnata, tansy mustard.
(10) Positive patch test reactions were 2+ for dandelion (Taraxacum officinale), false ragweed (Ambrosia acanthicarpa), giant ragweed (Ambrosia trifida), short ragweed (Ambrosia artemisifolia), sagebrush (Artemisia tridentata), wild feverfew (Parthenium hysterophorus), yarrow (Achillea millifolium), and tansy (Tanacetum vulgare) and 1+ for Dahlia species and English ivy (Hedera helix).
(11) Selected case reports from closely controlled experimental feedings of Senecio jacobaea (tansy ragwort), S longilobus (threadleaf groundsel) and S riddellii (Riddell's groundsel) to cattle are presented to show that all 3 of these pyrrolizidine alkaloid-containing plants may not necessarily induce proximate toxicity, but may cause typical signs and death many months after the plants are ingested.
(12) We suspect that other factors may be necessary to predispose cattle to photosensitization by tansy mustard, and future work will attempt to determine the cause of the photosensitization.
(13) The animal's tolerance for the plant was dependent on the amount of tansy ragwort fed, and the duration of the dosing period.
(14) In two experiments, the effect of feeding the pyrrolizidine alkaloid (PA)-containing plant tansy ragwort (Senecio jacobaea) on the metabolism of vitamin A in rats was examined.
(15) Tansy (Tanacetum vulgare L.) produces an essential oil containing the optically pure monoterpene ketone, (-)-camphor, as a major constituent.
(16) Other plants used are osha, chuchupate-lovage; ponso or tanse-tansy; poleo-spearmint or pennyroyal mint; amolillo-wild licorice; dormilon-tall cone flower; malva; and, lanten-plantain.
(17) All 8 calves fed tansy ragwort-contaminated pellets developed terminal hepatopathy in either a chronic pattern (n = 6) or a chronic-delayed pattern (n = 2), with the onset of a moribund state or sudden death at 11 to 17 weeks and 27 to 51 weeks, respectively.
(18) Nectar feeding by mosquitoes collected from tansy (Tanacetum vulgare) flowers was studied in July and August 1983-85 at two sites in central and south-western Sweden.
(19) Similarly, tansy (Tanacetum vulgare) is shown to contain two electrophoretically distinct dehydrogenases for the respective oxidations of (-)-borneol to (-)-camphor and of (+)-cis-sabinol to (+)-sabinone en route to (+)-3-thujone.
(20) Field cases have confirmed that tansy mustard was present and grazed in pastures where affected animals have grazed.