(a.) Having a valence of five; -- said of certain atoms and radicals.
Example Sentences:
(1) By 2020, the Gavi Alliance estimates that pentavalent vaccines will avert more than 7 million deaths.
(2) The inhibition of osmotic stimulated water flow in the isolated toad bladder by 0.1 mM sodium stibogluconate (pentavalent antimony) is described.
(3) Whole body scintigraphy with [99mTc] (v)dimercaptosuccinic acid (pentavalent DMSA) was performed in seven patients with histologically confirmed medullary carcinoma of the thyroid (MCT).
(4) Ureastibamine, a pentavalent antimonial, reduced the parasitic load in the 60-day model of infection of L. donovani in hamsters.
(5) This case-control (case-referent) study concerns a worker population with high exposure to dust of iron oxides, particularly hematite, and with some impurities of pentavalent arsenic and other metals.
(6) A series of 31 patients presenting with skin lesions with positive smears for leishmania parasites were treated with sodium stibogluconate (each ml of injection containing the equivalent of 100 mg pentavalent antimony).
(7) When healed lesions of 14 of these subjects were re-biopsied 1 to 12 months after the end of pentavalent antimonial therapy, MHC class II antigens could no longer be seen on keratinocytes.
(8) Lines expressing lmpgpA showed resistance to arsenite and trivalent antimonials, but not to pentavalent antimonials, zinc, cadmium, or the typical multidrug-resistant P-glycoprotein substrates vinblastine and puromycin.
(9) The retention of the tetravalent and pentavalent vanadium forms was also investigated 1 d after oral administration.
(10) Although a serious condition, with possible mutilation and even death as subsequent complications, treatment is still mainly with pentavalent antimonials, introduced 40 years ago.
(11) The first-line treatment consists of pentavalent antimony.
(12) To search for the tumour localization mechanism of Tc(V)-DMS, a polynuclear pentavalent technetium complex of dimercaptosuccinic acid [Tc(V)-DMS], the development of medullary thyroid carcinoma (MTC) bearing mouse model was considered.
(13) The problems of managing patients with visceral leishmaniasis which is unresponsive to conventional doses of pentavalent antimonials are discussed and some tentative suggestions put forward.
(14) Using the resonance theory, basic fuchsin is often written with an apparently pentavalent nitrogen atom at a quinonoid ring.
(15) The effect of ureastibamine was compared with that of another pentavalent antimonial, sodium stibogluconate.
(16) The trivalent arsenic compounds caused higher concentrations than the pentavalent in the upper gastrointestinal tract but not in other tissues.
(17) As based on the role of pentavalent nitrogen on substrate structure, it is apparent that PAP is to other acid phosphatases what the cholinesterases are to other esterases.
(18) Pentavalent antimonial agents such as sodium stibogluconate (Pentostam; Burroughs Wellcome Co., London, United Kingdom) are the drugs of choice for the treatment of leishmaniasis, but their biochemical mechanisms of action are virtually unknown.
(19) Its distinctive characteristic, different from the kidney imaging agent (99mTc-DMSA) is demonstrated and the biological implication of hydrolytic polynucleation of pentavalent technetium, through an anionic specie Tc(V)O3-(4), in the tumor cell is discussed.
(20) The antileishmanial activities of various synthetic constructs were compared with those of the free drugs and the pentavalent antimonial Pentostam, which was used as the positive control.
Tantalic
Definition:
(a.) Of or pertaining to tantalum; derived from, or containing, tantalum; specifically, designating any one of a series of acids analogous to nitric acid and the polyacid compounds of phosphorus.
Example Sentences:
(1) Director Gareth Edwards , who made Godzilla, introduced a tantalizing concept reel to preview the mysterious film, which is part of a series of films exploring other stories outside of the core Star Wars saga.
(2) Tantalizing preliminary data suggest that GH therapy has a role in the management of short, poorly growing children with other causes for their growth failure.
(3) The structural basis underlying a frequently occurring form of chromosome size polymorphism is now understood and other polymorphisms are providing tantalizing clues to the mechanisms underlying drug resistance.
(4) Although a similar accuracy to other approaches (utilizing a mean-square error) is achieved using this new measure, the accuracy on the training set is significantly and tantalizingly higher, even though the number of adjustable parameters remains the same.
(5) This is all the more tantalizing given the proposed structure of this receptor which, like all other G protein-coupled receptors, is thought to have the putative transmembrane helices forming a bundle-like structure in the plasma membrane.
(6) Geithner has tantalizing snippets of self-awareness – “I must have sounded like a bank lobbyist when opposing financial reform ”.
(7) Although the isoquinoline hypothesis has stimulated and even tantalized the scientific inquiry of a small number of investigators, it has been an area of widespread controversy.
(8) The role of adjuvant therapy is not yet established despite tantalizing biologic effects documented in their trials.
(9) Phospholipid turnover is one "panel" in the islet; however, an obligate role for phospholipase activation in glucose-induced insulin secretion is not yet rigorously established, despite tantalizing, inferential evidence.
(10) For several decades a tantalizing goal for the treatment of primary open-angle glaucoma has been the development of a topically active carbonic anhydrase inhibitor.
(11) The left side of the infield is once again tantalizing Beltran but he is swinging away here.
(12) Currently, there is no evidence in humans that converting enzyme inhibitors are superior to alternative antihypertensive agents in retarding progression, but tantalizing preliminary evidence on this has been reported in nondiabetic patients with renal failure.
(13) There are tantalizing indications that restricting dietary intake may improve human health and longevity.
(14) I know scientists have got to whet the appetite for future publications, but this is just too tantalizing.
(15) Two instruments, one of Russian origin, using very fine Tantale clips, permit one to carry out easily mechanical suture during operations on the digestive tract.
(16) Several tantalizing clues have been extracted from studies of the molecular pathogenesis, immunology, and biochemistry of endometriosis.
(17) The question of the existence of a complex class of poly(A)- brain mRNAs is particularly tantalizing in light of the heterogeneity of brain cells and the possibility that the stability of these poly(A)- mRNAs might vary with changes in synaptic function, changing hormonal stimulation or with other modulations of neuronal function.
(18) Our proposition that parkinsonian akinesia could be attributable to an impairment in the motor preparatory process therefore remains a tantalizing possibility.
(19) For the future there is the tantalizing promise that once the principles of coordination are understood, we can move on to the more intriguing questions of how a certain 'toss of the head' and 'look in the eye' not only transfer gaze but can also be so meaningful.
(20) The potential has remained tantalizing by the occasional clinical success, at least in depressor terms, of the early ganglionic blocking agents.