(n.) The antecedent of the ferment pepsin. A substance contained in the form of granules in the peptic cells of the gastric glands. It is readily convertible into pepsin. Also called propepsin.
Example Sentences:
(1) The agent present in the serum which causes dissolution of the fibrin clot was isolated and identified as pepsinogen.
(2) Serum pepsinogen 1, serum gastrin, ABO blood groups, secretor status of ABH blood group substances and behavioral factors were studied in 15 patients with duodenal ulcer and 61 their relatives affected and unaffected to duodenal ulcer.
(3) Somatostatin inhibited carbachol- and cholecystokinin octapeptide-induced pepsinogen secretion from dispersed gastric mucosal cells in a dose-dependent manner.
(4) For that reason we determine basal serum pepsinogen I (PG I) levels in 25 ulcerous patients and 75% of their offspring and to a control group matched by age and sex.
(5) The pepsinogens differ in their organic phosphate content, which accounts for their chromatographic separation.
(6) Pepsinogen I was not significantly influenced by glucagon.
(7) The increase of serum pepsinogen levels are probably due to a spillover effect resulting from a blockade in exocrine secretion into the lumen.
(8) Pepsinogen secretion from permeabilized chief cells could be stimulated with increasing concentrations of calcium (300 nM to 10 microM), adenosine 3',5'-cyclic monophosphate (cAMP; 1 microM to 1 mM), phorbol 12-myristate 13-acetate (10 nM to 1 microM), or by addition of carbamylcholine (0.1 mM) to the incubation solution.
(9) Pepsinogen secretion was stimulated by the agonists with an order of potency: acetylcholine greater than or equal to carbachol greater than oxotremorine greater than bethanechol.
(10) Human gastric mucosa contains three immunochemically distinguishable aspartic proteinases, pepsinogen I (pepsinogen A), pepsinogen II (pepsinogen C, progastricsin), and a nonpepsinogen proteinase also termed slow moving proteinase (SMP).
(11) In addition, we examined the relationship between tumor positivity and preoperative serum levels of pepsinogens I and II.
(12) Soluble extracts of gastric mucosa were prepared for estimation of pepsinogen content and [57Co]cyanocobalamin (vitamin B12) binding.
(13) A significant association has previously been found between a betazole-induced decrease in serum group I pepsinogen (PG I) levels and a low peak acid output (PAO) in symptomatic patients with vagotomy and gastric resection or a drainage procedure.
(14) The muscarinic receptor system involved in pepsinogen secretion from isolated guinea pig gastric chief cells was investigated by assessing the effect of muscarinic receptor antagonists on carbamylcholine (CCh)-induced pepsinogen secretion.
(15) One of them increases in activity after weaning and is a pepsinogen immunologically related to the pepsinogens of other vertebrates.
(16) The influence of the non-steroidal anti-inflammatory drug Acemetacin in depot form on the course of the pepsinogen levels in serum was examined during 14 day therapy.
(17) The content of HCl, pepsinogen, fucose, cAMP and cGMP was measured in gastric juice, that of bicarbonates, amylase, lipase, trypsin, cAMP and cGMP in pancreatic juice.
(18) Northern analysis revealed that the level of expression of genes for type-A pepsinogens and for progastricsin was significant at the fetal stage and increased with development.
(19) MMI-stimulated pepsinogen secretion could be dissociated from the acid secretion by the use of cimetidine and omeprazole which effectively block the acid secretion without affecting the pepsinogen output.
(20) For the native zymogen the rate of this conversion had been shown to be identical to the rate of cleavage of the scissile bond of pepsinogen.
Stomach
Definition:
(n.) An enlargement, or series of enlargements, in the anterior part of the alimentary canal, in which food is digested; any cavity in which digestion takes place in an animal; a digestive cavity. See Digestion, and Gastric juice, under Gastric.
(n.) The desire for food caused by hunger; appetite; as, a good stomach for roast beef.
(n.) Hence appetite in general; inclination; desire.
(n.) Violence of temper; anger; sullenness; resentment; willful obstinacy; stubbornness.
(n.) Pride; haughtiness; arrogance.
(v. t.) To resent; to remember with anger; to dislike.
(v. t.) To bear without repugnance; to brook.
(v. i.) To be angry.
Example Sentences:
(1) At the same time the duodenum can be isolated from the stomach and maintained under constant stimulus by a continual infusion at regulated pressure, volume and temperature into the distal cannula.
(2) This suggests that a physiological mechanism exists which can increase the barrier pressure to gastrooesophageal reflux during periods of active secretion of the stomach, as occurs in digestion.
(3) The authors conclude that H. pylori alone causes little or no effect on an intact gastric mucosa in the rat, that either intact organisms or bacteria-free filtrates cause similar prolongation and delayed healing of pre-existing ulcers with active chronic inflammation, and that the presence of predisposing factors leading to disruption of gastric mucosal integrity may be required for the H. pylori enhancement of inflammation and tissue damage in the stomach.
(4) The following possible explanations were discussed: a) the tested psychotropic drugs block prostaglandin receptors in the stomach; b) the test substances react with prostaglandin in the nutritive solution; c) the substances stimulate metabolic processes in the stomach wall that break down prostaglandin.
(5) It was considered worthwhile to report this case due to the problems which arose concerning the choice of a thoracic rather than abdominal route owing to the impossibility of associating cardiomyotomy with anti-reflux plastica surgery because of the reduced dimensions of the stomach.
(6) Gastric reservoir reduction, wrapping the stomach with an inert fabric, is one such procedure.
(7) Sialosyl-Tn antigen expression also was observed in intestinal metaplasia of the stomach and in transitional mucosa adjacent to the colorectal carcinoma, which are considered to be cancer-related lesions.
(8) The carcinoma and lymphoma of the stomach were both small, and the depth of invasion was localized to the mucosa and submucosa, respectively.
(9) Mean run time and total ST time were faster with CE (by 1.4 and 1.2 min) although not significantly different (P less than 0.06 and P less than 0.10) from P. Subjects reported no significant difference in nausea, fullness, or stomach upset with CE compared to P. General physiological responses were similar for each drink during 2 h of multi-modal exercise in the heat; however, blood glucose, carbohydrate utilization, and exercise intensity at the end of a ST may be increased with CE fluid replacement.
(10) G-17-I infusion, the stomach was continuously infused with isotonic saline.
(11) The CL was also longer in the duodenum, whereas the CD was shortened, indicating a reduction of the wave movements from the stomach antrum to the duodenum in the ranitidine periods.
(12) A great deal of information about the spiral bacteria of the stomach has accumulated in the past 5 years.
(13) A case is presented with radiographically demonstrated angioedema in the stomach and small bowel accompanied by allergic rhinitis, which was apparently an allergic response to the barium sulfate suspension.
(14) Therefore, we tested the ability of ultrasound imaging to identify noninvasively the stomach contents of laboring and nonlaboring pregnant volunteers.
(15) Of the strains tested, only the germ-free ND 1 mouse appeared to be susceptible to infection, and this was confined to the stomach mucosa; lesions contained large numbers of hyphal and mycelial forms with blastospores.
(16) I am absolutely sick to the stomach that this iconic Australian news agency would attack the navy in the way that it has,” he said.
(17) Pathogenic Mycobacterium ulcerans were recovered from the stool of anole lizards up to 11 days after inoculation by stomach tube.
(18) In adenocarcinoma of the distal esophagus and stomach, EUS prediction of stages T1 to T3 correlated well with the actual rate of R0 resection.
(19) These results suggest that formaldehyde has tumor-promoting activity in carcinogenesis in the glandular stomach.
(20) One hundred and two rats were subjected to one of following three surgical procedures: Antiperistaltic duodenogastric reflux (ADGR) was made for duodenal juice to reflux through the pylorus into the stomach.