What's the difference between permeant and permeation?
Permeant
Definition:
(a.) Passing through; permeating.
Example Sentences:
(1) Inhibition was not related to the permeant properties of the anion, but the relative inhibitory potency of the anions was similar to that in some other studies of secretory granule ATPases.
(2) 10 microM forskolin, a potent activator of adenylate cyclase, mimicked the effects of 5-HT as did a membrane-permeant cyclic AMP analogue, 8-parachlorophenylthio cyclic AMP (cpt-cAMP).
(3) In the present studies, Cl replaced the much less permeant anion methanesulfonate (Mes) either (a) at constant [K], in which increased [K][Cl] permits net KCl and water flux across internal membranes, or (b) at constant [K][Cl] (choline substitution), in which the imposed gradients and diffusion potentials should dissipate slowly.
(4) When permeant anions in the bath (Cl-) were replaced with relatively impermeant anions (gluconate, MOPS, propionate, or Hepes), the Po vs. voltage relationship was shifted by approximately -35 mV.
(5) The connective hyperpolarizes in the propionate saline, whereas the abdominal region undergoes the transient depolarization that is expected when a permeant anion (Cl) is replaced with an impermeant one (propionate).
(6) The PTH was potently blocked by the membrane-permeant forms of cAMP, dibutyryl- and 8-bromo-cAMP.
(7) Though permeant through the stretch-activated channel, Ca2+ inhibited in a concentration-dependent manner the currents carried by other cations.
(8) Here we report the existence in hippocampal neurons of K+ permeant channels whose activity is regulated by extracellular glucose.
(9) Small muscle bundles (20-50 fibers) were loaded with the membrane-permeant form of the dye.
(10) FCryp-1 carries four carboxylate groups to confer aqueous solubility and the indicator is membrane-permeant when the carboxyls are esterified with acetoxymethyl ester groups.
(11) In the presence of K+ salts, nigericin, like valinomycin, induces lysis of intact granules, an effect that is not dependent on the presence of a permeant anion, but is dependent on the pH gradient across the membrane.
(12) These changes are discussed in relation to other cellular modifications (distribution of permeant anions and accumulation of cyclic AMP) induced by foreign anions.
(13) It is concluded that the renin secretory process has a demand for permeant anions.
(14) Recently, we have shown that a membrane-permeant derivative of the antiasthmatic drug cromoglycate (CG) effectively inhibits the Fc epsilon-receptor-mediated secretory response of rat mucosal mast cells (line RBL-2H3) at a stage preceding the transient rise in the cytoplasmic free calcium concentration [Hemmerich, S., Sijpkins, D., & Pecht, I.
(15) Regardless of the permeant considered, activation energies for ks values were 3- to 5-fold greater than those for initial swelling rates.
(16) These results clearly show that cell-permeant cromoglycate inhibits the Fc epsilon RI-mediated Ca2+ influx into the cell and further underscore the dominant role of this process in the coupling of stimulus to secretion in RBL cells.
(17) The lifetime increases with permeant ion concentration, and at the one molar level it also increases with voltage.
(18) Cytotrophoblasts purified from human term placentae were fixed and made permeant with Triton X-100 and examined by indirect immunofluorescence after incubation with a monoclonal antibody to DBP.
(19) Both kinds of hydrocolloids, however, allow delivery of lysosomal, low-molecular-weight highly charged non-permeant fluorescent markers to phagosomes, probably by a fusion process.
(20) A permeant osmotic solute will induce either positive or negative isotope interaction, according to whether membrane heterogeneity is more marked for the test solute or the osmotic solute, respectively.
Permeation
Definition:
(n.) The act of permeating, passing through, or spreading throughout, the pores or interstices of any substance.
Example Sentences:
(1) In both instances the permeation rates of proteins can be better correlated to hydrodynamic radii than to molecular weights.
(2) In anaerobiosis, at 25 mM sulphanilic acid, or with addition of p-toluene sulphonic acid only one regression line is obtained for the permeation in both directions.
(3) The calpains were allowed to autolyze to completion, and the autolysis products were separated and were characterized by using gel permeation chromatography, calpastatin affinity chromatography, and sequence analysis.
(4) At 5 micrometer and 2.5 mM sulphanilic acid under aerobic conditions, the regression lines for the permeation from lumen to blood pass almost through the origin, while the regression lines for the permeation from blood to lumen intersect the ordinate at a positive Y-value.
(5) The breakthrough time and permeation rate at steady-state were calculated as described in the ASTM standard test method.
(6) Insulin-like growth factor-binding proteins (IGFBPs) in rat serum, lymph, amniotic fluid and cerebrospinal fluid (CSF), and in rat cell-conditioned media were characterized using a combination of gel-permeation chromatography, Western immunoblots and Western-ligand analysis.
(7) Glycerol permeation and thus its osmotic action may be less in the soleus than in other muscles.
(8) Previous histological evidence of the uptake of these particles and their absorption across the gastrointestinal tract and passage via the mesentery lymph supply and lymph nodes to the liver and spleen was confirmed by analysis of tissues for the presence of polystyrene by gel permeation chromatography.
(9) 10% NNDEMT doubled the amount of PFA in the skin, increased fourfold the amount permeated across the skin, and increased the flux fivefold.
(10) Various methodological weaknesses permeate the relevant literature.
(11) Time courses for in vivo total mucosal uptake exhibited linearity over a wide variety of absorption rates after correction for the permeation by intact metal-chelate complex.
(12) Gel permeation chromatography of the CIT-agarose eluates revealed one protein peak that coincided with PDE activity at an elution position of 135,000 daltons.
(13) Phospholipase A2 has been purified from the venom of Horned viper (Cerastes cerastes) by gel permeation chromatography followed by reverse-phase HPLC.
(14) The buccal absorption characteristics and physicochemical properties of the beta-adrenoceptor blocking agents propranolol and atenolol have been investigated to evaluate their permeation properties across biological lipid membranes.
(15) The permeation enhancer STDHF increases mucosal permeability and reduces the average molecular weight of the insulin species.
(16) I argue that the energy profile in the permeation pathway of most biological channels should vary relatively smoothly with only a few localized energy barriers or wells.
(17) Channels containing a variety of viable cells permeated the rice bodies.
(18) Estrogen receptor from human breast cancer tissue and from normal human uterus was isolated and characterized by a combination of physical separation methods including ammonium sulfate precipitation, gel permeation chromatography, isoelectric focusing and gel electrophoresis.
(19) However, we did not examine the mechanisms by which the apparent high permeation of sodium chloride occurs.
(20) For the skins without stratum corneum, the permeation rates and permeation amounts of l-NG and dl-NG were higher than those for the intact skin (P less than 0.01), but no significant difference was seen between l-NG and dl-NG.