(n.) The act of perturbing, or the state of being perturbed; esp., agitation of mind.
(n.) A disturbance in the regular elliptic or other motion of a heavenly body, produced by some force additional to that which causes its regular motion; as, the perturbations of the planets are caused by their attraction on each other.
Example Sentences:
(1) These membrane perturbation effects not observed with bleomycin-iron in the presence of a hydroxyl radical scavenger, dimethyl thiourea, or a chelating agent, desferrioxamine, were correlated with the ability of the complex to generate highly reactive oxygen species.
(2) Ultraviolet difference spectrophotometry indicates that the inactivated enzyme retains its capacity for binding the nucleotide substrates whereas the spectral perturbation characteristic of 3-phosphoglycerate binding is abolished in the modified enzyme.
(3) It is suggested that laboratory experiments should be performed on perturbed systems only if simulations have shown that the methods of data analysis will be satisfactorily powerful and accurate.
(4) Thresholds were measured for detecting perturbations in a regular lattice of dots by modulating local dot density, local dot luminance, or some combination of the two.
(5) It is shown that when a constant current is applied such that a stable equilibrium and rhythmic firing are present, the following predictions are inherent in the HH system of equations: (a) Small instantaneous voltage perturbations to the axon given at points along its firing spike result in phase resetting curves (when new phase versus old phase is plotted) with an average slope of 1.
(6) Lower lip perturbation duration was manipulated to yield two different load conditions.
(7) The role of the Golgi complex in the post-translational oligosaccharide maturation of alpha-amylase was explored by use of the carboxylic ionophore, monensin (10(-7)M), a known perturbant of the structure and function of the Golgi complex.
(8) The importance of the ionic interaction due to the formation of the salt bridge between the Asp-27 and the pteridine ring in Escherichia coli dihydrofolate reductase-methotrexate complex has been studied by using the free-energy perturbation method.
(9) Presence of the monosynaptic reflex during platform perturbations at normal latencies suggests that balance problems in children with Down syndrome do not result from hypotonia, which researchers have defined as decreased segmental motoneuron pool excitability and pathology of stretch reflex mechanisms, but rather result from defects within higher level postural mechanisms.
(10) We have perturbed the dynamics of the nuclear lamins by means of cell fusion between mitotic and interphase cells and have studied redistribution of lamins in fused cells as a function of extracellular pH levels.
(11) In the coagulating gland, this compensatory response involved the proliferation of many cells which, in the absence of cytotoxic perturbation, would be non-proliferatie (Q cells).
(12) The effect of initial perturbation of the thrombus by a guide wire appears to be less important than the thrombus disruption and accelerated thrombolysis caused by the pulsatile delivery system.
(13) As before, subjects were instructed to either oppose the perturbation (Predictable Oppose) or relax the forearm muscles (Predictable Let-Go).
(14) Bivalent cations (Ca2+, UO2(2+) or Zn2+) in the subphase at pH 5.6 significantly modified the behaviour of mixed monolayers of fusogenic lipids with phospholipids; there was a parallel perturbing effect of fusogenic lipids on interactions between monolayers of phospholipids and bivalent cations.
(15) In particular, nitration of Tyr-51 provoked a structural perturbation in the globular region.
(16) Altering the biophysical characteristics of cell membranes by diet and membrane perturbing agents markedly influences thermosensitivity of cells.
(17) Paraphilias (PAs) and non-paraphilic sexual addictions (NPSAs) may be behaviors that share a common perturbation of central serotonin neuroregulation as a component of their pathophysiology.
(18) Two functions of these have been proposed: 1) that they are compatible osmolytes which regulate cell volume (against high external NaCl) without inhibiting proteins and 2) that methylamines (GPC and betaine) are counteracting osmolytes which stabilize proteins against perturbation from high renal urea.
(19) This high incidence of HER2 gene amplification with accompanying overexpression in non-invasive breast tumors suggests that perturbations of the HER2 oncogene are among the earliest and most common genetic lesions in human breast cancer.
(20) Hypophysectomy was selected as a model system for perturbing testicular cell types, since the cytological sequelae of this treatment post-hypophysectomy in the rat are well documented in the literature.
Upset
Definition:
(v. t.) To set up; to put upright.
(v. t.) To thicken and shorten, as a heated piece of iron, by hammering on the end.
(v. t.) To shorten (a tire) in the process of resetting, originally by cutting it and hammering on the ends.
(v. t.) To overturn, overthrow, or overset; as, to upset a carriage; to upset an argument.
(v. t.) To disturb the self-possession of; to disorder the nerves of; to make ill; as, the fright upset her.
(v. i.) To become upset.
(a.) Set up; fixed; determined; -- used chiefly or only in the phrase upset price; that is, the price fixed upon as the minimum for property offered in a public sale, or, in an auction, the price at which property is set up or started by the auctioneer, and the lowest price at which it will be sold.
(n.) The act of upsetting, or the state of being upset; an overturn; as, the wagon had an upset.
Example Sentences:
(1) A series of hierarchical multiple regressions revealed the effects of Surgency, Agreeableness, Conscientiousness, Emotional Stability, and Intellect on evoking upset in spouses through condescension (e.g., treating spouse as stupid or inferior), possessiveness (demanding too much time and attention), abuse (slapping spouse), unfaithfulness (having sex with others), inconsiderateness (leaving toilet seat up), moodiness (crying a lot), alcohol abuse (drinking too much alcohol), emotional constriction (hiding emotions to act tough), and self-centeredness (acting selfishly).
(2) Mean run time and total ST time were faster with CE (by 1.4 and 1.2 min) although not significantly different (P less than 0.06 and P less than 0.10) from P. Subjects reported no significant difference in nausea, fullness, or stomach upset with CE compared to P. General physiological responses were similar for each drink during 2 h of multi-modal exercise in the heat; however, blood glucose, carbohydrate utilization, and exercise intensity at the end of a ST may be increased with CE fluid replacement.
(3) Treatment is therefore often palliative, and endoscopic modalities cause considerably less general upset to the patient than surgery, radiotherapy or chemotherapy.
(4) We interpreted these results within an attributional framework that emphasizes the salience of upsetting events within a social network.
(5) She stayed calm during the upsetting search that led to Cynthia, who turned out to be flaky, chain-smoking and white (played by Brenda Blethyn).
(6) Trump might say that is what he wants to happen but for us, that’s deeply upsetting,” says Moore, who sits on the board of the Center Against Sexual and Family Violence and expects the case to have a chilling effect on reports of abuse.
(7) We’re all very upset right now,” said Daniel Ray, 24, in his third year of the divinity master’s degree program.
(8) Al-Jazeera's coverage has also upset the authorities.
(9) Our observations lead us to think that effectively, an event during which an important emotional state is induced, by upsetting the immune equilibrium, could more predispose a child (in this case the first born) to the action of pathogens.
(10) The interview was a friendly, intense discussion about upsetting situations the subject faced.
(11) A fired-up Lleyton Hewitt just fell short in his bid to steer Australia to an upset victory in their Davis Cup doubles showdown with the United States.
(12) She [Plath] was very worried about it because she thought it was going to upset her mother.
(13) Diagnostic characteristics of RSDS are: spontaneous burning pain, hyperalgesia, vasomotor disturbances, exacerbations by emotional upset, occurrence either spontaneously or after minor injury, occasional spontaneous resolution, extension to other body parts, and relief by sympathetic denervation.
(14) Plenty of people felt embarrassed, upset, outraged or betrayed by the Goncourts' record of things they had said or had said about them.
(15) The territory is actualy reached by deep demographic and social upsettings and chemiotherapy used alone is not enough efficient to obtain a definitive decrease of the endemy or even to avoid, for a long time, a new increase.
(16) The amount he is being paid for three short columns a week would “only get you sandal wearers all upset” if revealed, he says.
(17) The CPS doesn't just have to consider the public interest in prosecuting individual cases, but also the more general public interest in being able to say potentially upsetting things without fear of prosecution.
(18) As with other selective serotonin reuptake inhibitors (SSRIs), the most common side effect is gastrointestinal upset, especially nausea.
(19) It's possible that it upsets her to think about the past, or perhaps, these days, she saves her animation for the times when she is holding a microphone and standing in front of a swollen, angry crowd.
(20) The conclusion from this, the first reported series on adjuvant Tamoxifen therapy for MBC, is that significant improvement in disease-free survival can be achieved with minimal upset to the patients.