(1) These membrane perturbation effects not observed with bleomycin-iron in the presence of a hydroxyl radical scavenger, dimethyl thiourea, or a chelating agent, desferrioxamine, were correlated with the ability of the complex to generate highly reactive oxygen species.
(2) Ultraviolet difference spectrophotometry indicates that the inactivated enzyme retains its capacity for binding the nucleotide substrates whereas the spectral perturbation characteristic of 3-phosphoglycerate binding is abolished in the modified enzyme.
(3) It is suggested that laboratory experiments should be performed on perturbed systems only if simulations have shown that the methods of data analysis will be satisfactorily powerful and accurate.
(4) Thresholds were measured for detecting perturbations in a regular lattice of dots by modulating local dot density, local dot luminance, or some combination of the two.
(5) It is shown that when a constant current is applied such that a stable equilibrium and rhythmic firing are present, the following predictions are inherent in the HH system of equations: (a) Small instantaneous voltage perturbations to the axon given at points along its firing spike result in phase resetting curves (when new phase versus old phase is plotted) with an average slope of 1.
(6) Lower lip perturbation duration was manipulated to yield two different load conditions.
(7) The role of the Golgi complex in the post-translational oligosaccharide maturation of alpha-amylase was explored by use of the carboxylic ionophore, monensin (10(-7)M), a known perturbant of the structure and function of the Golgi complex.
(8) The importance of the ionic interaction due to the formation of the salt bridge between the Asp-27 and the pteridine ring in Escherichia coli dihydrofolate reductase-methotrexate complex has been studied by using the free-energy perturbation method.
(9) Presence of the monosynaptic reflex during platform perturbations at normal latencies suggests that balance problems in children with Down syndrome do not result from hypotonia, which researchers have defined as decreased segmental motoneuron pool excitability and pathology of stretch reflex mechanisms, but rather result from defects within higher level postural mechanisms.
(10) We have perturbed the dynamics of the nuclear lamins by means of cell fusion between mitotic and interphase cells and have studied redistribution of lamins in fused cells as a function of extracellular pH levels.
(11) In the coagulating gland, this compensatory response involved the proliferation of many cells which, in the absence of cytotoxic perturbation, would be non-proliferatie (Q cells).
(12) The effect of initial perturbation of the thrombus by a guide wire appears to be less important than the thrombus disruption and accelerated thrombolysis caused by the pulsatile delivery system.
(13) As before, subjects were instructed to either oppose the perturbation (Predictable Oppose) or relax the forearm muscles (Predictable Let-Go).
(14) Bivalent cations (Ca2+, UO2(2+) or Zn2+) in the subphase at pH 5.6 significantly modified the behaviour of mixed monolayers of fusogenic lipids with phospholipids; there was a parallel perturbing effect of fusogenic lipids on interactions between monolayers of phospholipids and bivalent cations.
(15) In particular, nitration of Tyr-51 provoked a structural perturbation in the globular region.
(16) Altering the biophysical characteristics of cell membranes by diet and membrane perturbing agents markedly influences thermosensitivity of cells.
(17) Paraphilias (PAs) and non-paraphilic sexual addictions (NPSAs) may be behaviors that share a common perturbation of central serotonin neuroregulation as a component of their pathophysiology.
(18) Two functions of these have been proposed: 1) that they are compatible osmolytes which regulate cell volume (against high external NaCl) without inhibiting proteins and 2) that methylamines (GPC and betaine) are counteracting osmolytes which stabilize proteins against perturbation from high renal urea.
(19) This high incidence of HER2 gene amplification with accompanying overexpression in non-invasive breast tumors suggests that perturbations of the HER2 oncogene are among the earliest and most common genetic lesions in human breast cancer.
(20) Hypophysectomy was selected as a model system for perturbing testicular cell types, since the cytological sequelae of this treatment post-hypophysectomy in the rat are well documented in the literature.
Worry
Definition:
(v. t.) To harass by pursuit and barking; to attack repeatedly; also, to tear or mangle with the teeth.
(v. t.) To harass or beset with importunity, or with care an anxiety; to vex; to annoy; to torment; to tease; to fret; to trouble; to plague.
(v. t.) To harass with labor; to fatigue.
(v. i.) To feel or express undue care and anxiety; to manifest disquietude or pain; to be fretful; to chafe; as, the child worries; the horse worries.
(n.) A state of undue solicitude; a state of disturbance from care and anxiety; vexation; anxiety; fret; as, to be in a worry.
Example Sentences:
(1) But the position of locum GPs remains worryingly unsure.
(2) I know I have the courage to deal with all the sniping but you worry about the effects on your family."
(3) If Lagarde had been placed under formal investigation in the Tapie case, it would have risked weakening her position and further embarrassing both the IMF and France by heaping more judicial worries on a key figure on the international stage.
(4) In Paris, a foreign ministry spokesman, Romain Nadal, said the French authorities were “fully mobilised to help Serge Atlaoui, whose situation remains very worrying”.
(5) Amid all of the worry about her health, the difficult decisions around the surgery, and how to explain everything to the children, the practicalities of postponing the holiday was a relatively minor consideration.
(6) The secrecy worries me if those decisions are being made without giving us the ability to hold them to account,” says Conservative London Assembly member Andrew Boff.
(7) At the People’s Question Time in Pendle, an elderly man called Roland makes a short, powerful speech about the sacrifices made for the right to vote and says he’s worried for the future of the NHS.
(8) Wimbledon said the world No1 Williams had been suffering from a viral illness and it was a sad and bizarre end to the American’s tournament, not to mention a worrying sight, seeing her hardly able to play.
(9) The only explanation he can come up with is that Cameron is worried about his legacy.
(10) There is no doubt about it that there are authorities that have a greater need for public health money than ourselves, but Surrey still has issues and worries about certain social factors within public health," he said.
(11) Davies, who worked closely with AHTSYL's producers to ensure an accurate picture, worries that some medical stories are sold solely as "emotional journeys".
(12) "We believe BAE's earnings could stagnate until the middle of this decade," said Goldman, which was also worried that performance fees on a joint fighter programme in America had been withheld by the Pentagon, and the company still had a yawning pension deficit.
(13) The big worry here is: even if the data broker reports aggregate data, a) it has this information on an individual level – how else might it use it?
(14) It took a little bit of time to come up on the scoreboard, so I was a bit worried.
(15) Former acting director of the CIA, Michael Morell, also weighed in for Clinton in a New York Times opinion piece on Friday, declaring: “Donald J Trump is not only unqualified for the job, but he may well pose a threat to our national security.” Republicans stumbling from the wreckage of a terrible week are worrying about how to contain the damage further down the ballot paper in November as people running for seats in Congress and at state level risk being swept away.
(16) Non-worriers evidenced the same disruptive effects in the 15-worry condition as worriers in that condition and worriers in Study 1.
(17) Jenny Jones, a Green party member of the London Assembly who has campaigned to make cycling safer, said she had spoken to the deputy head of the Met's traffic unit to express her worries about the operation.
(18) What was very worrying was at half‑time when you go in the dressing room, I could sense there was no response.
(19) She said she was not worried by Rubio’s one-time position on his immigration bill, later retracted, that he could not support reform if it included citizenship for gay couples.
(20) It sells itself to British tourists as a holiday heaven of golden beaches, flamenco dresses and well-stocked sherry bars, but southern Andalucía – home to the Costa del Sol – has now become the focus of worries about the euro.