(n.) An instrument or device to be introduced into and worn in the vagina, to support the uterus, or remedy a malposition.
(n.) A medicinal substance in the form of a bolus or mass, designed for introduction into the vagina; a vaginal suppository.
Example Sentences:
(1) The substance benzalconium chloride (BZC) was contained in vaginal sponges (n = 46), pessaries (n = 4) and cream (n = 6) at a dose rate of 1.18%.
(2) Gemeprost 1 mg vaginal pessaries were inserted at 3 hr intervals for a maximum of 5 doses.
(3) It is concluded that PGE2 vaginal tablets--a chemically stable alternative to pharmacy prepared pessaries--appear to be effective as regards cervical ripening as well as for labor induction.
(4) Each ewe was inseminated in the uterus with fresh semen 24 h after pessary withdrawal.
(5) All 50 women who received gemeprost vaginal pessaries every 3 hours aborted within 48 hours, while 10% who received them every 6 hours did not abort.
(6) Of the potentially useful compounds, only derivatives of prostaglandins E and F administered by vaginal pessary have so far been shown to be effective.
(7) A single course of 4 x 1 mg gemeprost pessaries was administered every six hours.
(8) This double-blind study is concerned with the efficacy and safety of a new prostaglandin E1-analogue (16,16'-dimethyl-trans-delta 2PGE1-methylester) (Gemeprost) (ONO-802), which was administered as a single 1 mg vaginal pessary three hours prior to legal abortion.
(9) Both groups showed a rise in plasma PGE2 levels in keeping with the release profiles of the pessaries.
(10) Moreover, women who received RU-486 required significantly fewer gemeprost pessaries (median of 3) than controls (median of 5); the former women also required significantly less analgesia.
(11) In a randomized, double-blind clinical trial from general practice, 500 mg metronidazole pessaries applied once daily for seven days were compared with placebo in the treatment of bacterial vaginosis.
(12) These results suggest that in many women the number of pessaries used to induce mid-trimester abortion could be reduced by lengthening the interval between insertion of pessaries within the first 24 h, without loss of clinical efficacy.
(13) A questionnaire study was carried out to investigate the needs of women undergoing a medical abortion induced by mifepristone in combination with either gemeprost pessaries or oral misoprostol.
(14) This correction is made either by putting a pessary, either by a surgical cure unless the risk should be too important for the patient.
(15) The mean (SD) induction-abortion interval (IAI) in the vaginal pessary group of 19.5 (8.4) h was significantly longer than the respective intervals of 14.4 (9.3) and 16.1 (6.8) h in the patients treated extra- or intra-amniotically (P less than 0.001).
(16) In order to define the patterns of TSH, T4, T3, rT3, GH and cortisol during the estrous cycle of sheep, pluriparous and primiparous ewes were synchronized with progestagen-impregnated pessaries (Veramix) at the start of the normal breeding season.
(17) In a prospective randomized trial of 106 patients who had spontaneously ruptured their membranes greater than or equal to 4 hours in the absence of labour, vaginal prostaglandin E2 pessaries and intravenous Syntocinon were compared.
(18) One hundred fourteen women received a placebo pessary and 101 received the hydrogel pessary, containing 10 mg of prostaglandin (PG) E2.
(19) Though isoconazole was formulated for single dose usage, econazole was formulated for a regimen of one pessary a night for three nights.
(20) After insertion of the pessary, 44 women received an oral analgesic drug and 9 an intramuscular opioid.
Therapeutic
Definition:
(a.) Alt. of Therapeutical
(n.) One of the Therapeutae.
Example Sentences:
(1) Treatment termination due to lack of efficacy or combined insufficient therapeutic response and toxicity proved to be influenced by the initial disease activity and by the rank order of prescription.
(2) After a discussion of the therapeutic relationship, several coping strategies which have been used successfully by many women are described and therapeutic applications are offered.
(3) Training in social skills specific to fostering intimacy is suggested as a therapeutic step, and modifications to the social support measure for future use discussed.
(4) Therapeutic possibilities for hepatogenous anaemia of complex genesis are discussed.
(5) No difference in therapeutic activity between CNC-ala-17-E2 and CNC-ala could be observed in a transplanted rat leukemia (L 5222).
(6) Different therapeutic success rates have been reported by various authors who used the same combination of therapy.
(7) SD is shown to have therapeutic and differential diagnostic significance in varying pathological conditions of cerebral dopaminergic systems.
(8) The clinical aspects, the modality of onset and diffusion of the lymphoma, its macroscopic and histopathological features and the different therapeutic approaches are discussed.
(9) Current status of prognosis in clinical, experimental and prophylactic medicine is delineated with formulation of the purposes and feasibility of therapeutic and preventive realization of the disease onset and run prediction.
(10) The following case highlights the diagnostic and therapeutic dilemmas encountered in a middle-aged patient who presented with dementia and apathetic hyperthyroidism.
(11) Local injections of contrykal into the ulcer had inhibited proteinase activity and had a positive therapeutic effect.
(12) These data, compared with literature findings, support the idea that intratumoral BCG instillation of bladder cancer permits a longer disease-free period than other therapeutical approaches.
(13) We report on experiences with diagnostic and therapeutic procedures and the results of vocational rehabilitation.
(14) On the other hand, the patients treated with cimetidine showed a marked, systematic increase in theophylline plasma levels, even exceeding the upper limit of its known therapeutic range in 4 cases.
(15) As novel antibody therapeutics are developed for different malignancies and require evaluation with cells previously uncharacterized as antibody-dependent cell-mediated cytotoxicity (ADCC) targets, efficient description of key parameters of the assay system expedites the preclinical assessment.
(16) Pharmacodynamic relationships are not well established for other therapeutic effects of theophylline, such as attenuation of pharmacologically induced bronchoconstriction.
(17) Intoxications arising from therapeutic activities pertaining to this cult are of the same kind as those encountered in the practice of Modern Medicine.
(18) The combination of an over-distended uterus caused by a multiple-fetus pregnancy with therapeutic bed-rest may cause mechanical ileus.
(19) Finally, these cases support the existence of a therapeutic upper limit for desipramine plasma concentrations, above which clinical deterioration occurs.
(20) How useful is the technique for evaluating therapeutic efficacy?