What's the difference between pharmacology and toxicology?

Pharmacology


Definition:

  • (n.) Knowledge of drugs or medicines; the art of preparing medicines.
  • (n.) A treatise on the art of preparing medicines.

Example Sentences:

  • (1) Spectral analysis of spontaneous heart rate fluctuations, a powerful noninvasive tool for quantifying autonomic nervous system activity, was assessed in Xenopus Laevis, intact or spinalized, at different temperatures and by use of pharmacological tools.
  • (2) The effects of sessions, individual characteristics, group behavior, sedative medications, and pharmacological anticipation, on simple visual and auditory reaction time were evaluated with a randomized block design.
  • (3) In animal experiments pharmacological properties of the low molecular weight heparin derivative CY 216 were determined.
  • (4) This activation demonstrated in humans confirms the pharmacological results of the interferon induction obtained with SL04 in vivo in mice and in vitro in human cell cultures.
  • (5) Many features of CFTR activity suggest that pharmacological interventions may be possible.
  • (6) testosterone, fentanyl, nicotine) may ultimately be administered in this way, important questions pertaining to pharmacology (tolerance), toxicity (irritation, sensitisation) and dose sufficiency (penetration enhancement) remain.
  • (7) These observations indicate that lipoprotein Lp(a) concentrations can be altered pharmacologically and that the progression of cardiovascular disease may be altered through changes in lipoprotein (a) levels.
  • (8) Significant differences in the pharmacological characteristics of the alpha 2 adrenoceptor were observed between the tissues with reference to both absolute drug affinities as well as rank order of drug potency.
  • (9) Pharmacodynamic relationships are not well established for other therapeutic effects of theophylline, such as attenuation of pharmacologically induced bronchoconstriction.
  • (10) The primary focus of both nonpharmacologic and pharmacologic therapy should be to control systemic blood pressure in a simple, affordable, and nontoxic fashion that provides an adequate quality of life.
  • (11) Only an extensive knowledge of the various mechanisms and pharmacologic agents that can be used to prevent or treat these adverse reactions will allow the physician to approach the problem scientifically and come to a reasonable solution for the patient.
  • (12) The pharmacological effects characterize reproterol as a bronchospasmolytic with preferential impact on the adrenergic beta2-receptors.
  • (13) Baroreflex function was studied in conscious early phase (less than 6 weeks) two-kidney, one-clip hypertensive rats before and 24 hours after surgical reversal of hypertension by removal of the constricting renal artery clip or after pharmacological reduction of blood pressure by an infusion of hydralazine or captopril.
  • (14) The study confirms that secretin influences pancreatic protein secretion and indicates in addition, that pharmacologic doses of the hormone, have the capacity to block acinar cell zymogen granule release.
  • (15) Results of sleep sampling under electroencephalographic control of the assessment of GH secretion are comparable to conventional pharmacological studies in terms of efficiency, sensitivity, and percentage false-negatives.
  • (16) Behavioral variables, including interreinforcement interval and drug self-administration history, appear to be important determinants of whether or not reinforcement will be demonstrated, particularly among the benzodiazepines; but the range of conditions under which behavioral and pharmacological variables interact to promote or lessen the likelihood of self-administration of these drugs remains to be determined experimentally.
  • (17) Because there were no interactions of time and type of migraine in either study, these results raise some questions about the existence of differential effectiveness of non-pharmacological treatment of menstrual vs non-menstrual migraine.
  • (18) Some factors of resistance (such as side benefits) happen in reactive and neurotic depressions and are independent of the pharmacological action.
  • (19) The fractional rate constants for the accumulation or disappearance of the metabolites could be determined after pharmacological blockade of catabolic enzymes or the acid metabolite carrier.
  • (20) However, reliable discrimination between immunological and idiosyncratic pharmacological mechanism is difficult to obtain.

Toxicology


Definition:

  • (n.) The science which treats of poisons, their effects, antidotes, and recognition; also, a discourse or treatise on the science.

Example Sentences:

  • (1) This new protocol has increased the effectiveness of the toxicology laboratory and enhanced the efficiency of the house staff.
  • (2) Microscopic examination of lesions from F1a and F2a animals, of gonads from F1b and F2b and of selected tissues from the F3a generation revealed no changes of toxicological significance.
  • (3) The significance of the present findings on the mutual suppression of metabolism between benzene and toluene is discussed in relation to solvent toxicology and biological monitoring of exposure to the solvents.
  • (4) The toxicological findings of this case are compared to the results of two chloroquine suicide cases and discussed in the context of the referring literature.
  • (5) The cause of death was confirmed by autopsy and toxicological analysis.
  • (6) No gross toxicological effects were noted in the experimental fish, although their weight gain was less than that of the controls.
  • (7) Khera (1973, 1975, 1977) reported that administration of ETU to pregnant rats could induce anomalies in the visceral organs and the central nervous system of fetuses in food toxicology.
  • (8) A full autopsy and toxicological examination have been ordered.
  • (9) The fellowships primarily last one year, are research oriented, and place a large emphasis on toxicology, emergency medical services, and critical care.
  • (10) The development of the hydrogelic occlusive device called the P-block is described including developmental steps of the design of the device as well as the experience gained concerning the hydrogel of the device, shelf life, animal and human toxicology, insertion techniques, analgesia, check-up for retention in situ, actual efficacy of the method, mode of action of the device, complication rates, patient acceptance, continuation rates, possible reversibility and future perspectives of the method.
  • (11) A scientific rather than a routine approach in toxicology is emphasized.
  • (12) A toxicology screen obtained after transfer was positive only for diazepam and phenobarbital.
  • (13) Finally, knowledge regarding the mechanism of toxicological action provided valuable information in relating toxicological properties among the aliphatic nitriles.
  • (14) Further studies are needed to determine the identity and toxicological properties of the non-volatile N-nitroso compounds.
  • (15) Isocyanates are highly reactive chemicals capable of causing a multitude of toxicologic effects including respiratory irritation, dermal irritation, contact sensitivity, and pulmonary hypersensitivity.
  • (16) To compare the efficacy of structured questionnaire screening and prenatal urine toxicology for the detection of substance use by pregnant women, and to describe substance use patterns in a group of women presenting to a university-based obstetric clinic.
  • (17) In toxicological studies, the test compound FOE 3440 A, a [(3,5-dichloro-2-pyridyl)oxy]phenoxypropanoate with herbicidal properties, produced a severe increase in weight and an intensive induction of monoxygenases activity in the mouse, but not in the rat.
  • (18) These toxicology studies allow an appropriate starting dose to be selected for clinical trials.
  • (19) In a multi-generation experiment with 120 hens of the species White Leghorn per group kept in cages, the influence of 5%, 7.5% and 15% 'fermosinR' torula yeast in the ration of mixed feed on various performance parameters in the 364-day laying period was investigated under long-term toxicologic aspects.
  • (20) In the future, it will be necessary to cooperate with the departments of epidemiology, toxicology and clinical medicine for the purpose of estimating the risk of these occupations and the health care administration of the exposed workers.