(n.) The act or practice of opening a vein for letting blood, in the treatment of disease; venesection; bloodletting.
Example Sentences:
(1) This is of clinical importance as IHC can be successfully treated by phlebotomy.
(2) PPMM occurred in about the same incidence in the patients treated with myelosuppressive therapy as by phlebotomy alone, the spent phase occurring in 16 patients treated by phlebotomy alone, 11 with chlorambucil, and 12 with 32P.
(3) The ferritin content of liver and spleen in normal and iron-loaded rats decreased during repeated phlebotomy.
(4) A marked reduction in the area covered by adventitial cells was recorded coinciding with the early reticulocyte response to phlebotomy.
(5) Chloroquine may be used as a provocative diagnostic test for patients with a questionably latent PCT but this is safe if phlebotomy is performed beforehand.
(6) One group received recombinant human erythropoietin to increase hematocrit, and another group was subjected to phlebotomy and fed a low-iron diet to induce anemia.
(7) Twenty-five patients with overt clinical and biochemical findings of porphyria cutanea tarda took part in a study comparing intensive phlebotomy with slow subcutaneous desferrioxamine treatment.
(8) Erythrocyte and plasma ferritin was followed in 13 patients with iron overload undergoing phlebotomies for at least 6 months in comparison with untreated patients and normal males.
(9) A multicompartmental model of erythrokinetics and bilirubin production has been developed to predict the consequences of chronic phlebotomy on daily bilirubin turnover.
(10) Hb values gradually increased, but did not completely recover to pre-phlebotomy levels by day 56.
(11) The two groups had similar mean predonation values of internal carotid flow velocity (ICFV): blood donation was followed in both groups by a slight, transient decrease of ICFV at the end of phlebotomy, due to donation-induced hypovolemia, and then by an increase of ICFV lasting 7 to 10 days.
(12) We conclude that the technical skills of phlebotomists and patient satisfaction with phlebotomy are outstanding, but that patient discomfort from the procedure needs to be minimized.
(13) It is emphasized that serum ferritin measurements are useful for monitoring of intensive phlebotomy therapy, and in particular to indicate the end of therapy before anemia develops.
(14) He was already diagnosed as having erythrocytosis secondary to pulmonary fibrosis 4 years previously and the values of his hematocrit (Ht) were maintained between 44.5 and 62.9% by repeated phlebotomy.
(15) Serum levels of transferrin receptor and erythropoietin were determined in 2 patients with hereditary hemochromatosis undergoing phlebotomy therapy.
(16) They received phlebotomies, plasmapheresis, and transfusions of erythrocytes and platelets.
(17) The operation was performed 2 weeks after the last phlebotomy.
(18) For in vitro studies, a triplet study design was used, in which WBC-reduced PCs were matched to standard PCs and to WBC-enriched PCs obtained from the same donor at the same phlebotomy.
(19) Although there was an increase in the level of serum immunoreactive erythropoietin with successive phlebotomies, the increase was not substantially out of the normal range.
(20) Two effective and reliable methods exist - repeated phlebotomy therapy and prolonged low-dose chloroquine.
Venesection
Definition:
(n.) The act or operation of opening a vein for letting blood; bloodletting; phlebotomy.
Example Sentences:
(1) It is concluded that a simple venesection regimen without volume replacement is a safe procedure for improving blood rheology.
(2) The patients were subgrouped by sex, age, medical history, smoking habits, delay from the onset of symptoms to the start of treatment, hematocrit at entry, venesection volume, neurologic score at entry into the study, blood pressure changes in the acute phase, presence of atrial fibrillation, location of brain lesion by computed tomography, type of diagnostic procedures, and hospital setting.
(3) Kidney transplant patients may develop post-transplant erythremia (PTE), and in order to avoid thromboembolism venesection, anticoagulation and native kidney removal have been suggested.
(4) In the final group the hematocrit value was reduced to the same extent by means of venesection and volume substitution with Ringer lactate.
(5) Maximal oxygen uptake (VO2 max) decreased from 4.27 l-min-1) at control to 4.03 l-min-1 after venesection (P less than 0.05) and increased to 4.61 l-min-1 after reinfusion (P less than 0.05).
(6) The control group received no dextran or venesection.
(7) These may persist in diminishing degree for several weeks, but have to be weighed against the detraining effect produced by the repeated venesection required to obtain an adequate amount of stored blood for autologous reinfusion.
(8) Hence it is suggested that treatment either by anticoagulation or by venesection is indicated.
(9) Liver biopsy, chemical hepatic iron determination, iron absorption studies, and number of venesections required were used to support these observations.
(10) Four of the patients with hemochromatosis were reexamined after completed treatment with venesection; this resulted in normalized biliary concentrations of iron and ferritin.
(11) This case history records a rare form of self-mutilation, venesection.
(12) In the venesected group the 2,3-DPG increased between Day 0 and Day 4.
(13) Phlebotomy appears to be the treatment of choice, with a regimen of regular venesection for the control of symptoms due to hyperviscosity and vascular occlusion.
(14) Venesection with subsequent administration of Ringer lactate and exercise is superior to exercise alone but markedly inferior to the combination therapy with HES.
(15) Therapeutic venesection for polycythaemia vera (PV) produces iron deficiency.
(16) In experimental animals and in the human studies, venesected individuals were used to reproduce the iron deficiency state where treatment would be indicated.
(17) However, in patients in whom venesection is not feasible, the chelating agent DFO can effectively remove excess iron.
(18) Mucosal iron uptake and body absorption were both considerably increased in the patients with iron-deficiency anaemia (33.5 - 15.6 and 29.8 - 17.0% respectively) and in the eight patients with idiopathic haemochromatosis treated by venesection therapy until the excess iron stores were removed (27.2 - 12.0 and 26.6 - 14.6% respectively).
(19) After venesection, the platelet and megathrombocyte counts increased rapidly and excessively in most patients and platelet aggregation improved markedly.
(20) Eight patients treated with cyclosporin-A and five treated with azathioprine had therapeutic venesections.