What's the difference between phosphite and radical?
Phosphite
Definition:
(n.) A salt of phosphorous acid.
Example Sentences:
(1) The incorporation of phosphine and phosphite ligands is described.
(2) In connection with this study, deoxyribonucleoside-3' dimethyl phosphites were synthesized and detailed properties of them are also described.
(3) The passive net transport of Li+ and Na+ across the human red cell membrane was accelerated by the divalent anions carbonate, sulphite, oxalate, phosphite and malonate.
(4) A period of adaptation was required prior to growth on phosphite when phosphate-grown cells were transferred to a medium containing a limiting amount of phosphate and excess phosphite.
(5) No phosphite-oxidizing activity could be detected in whole cells or cell-free extracts of phosphate-grown cells.
(6) The pH maxima observed for the phosphate analogs indicate a pK for this site of 5.5 at 37 degrees C. Intracellular pH changes associated with influx indicated that transport of the "fast" anion phosphite is largely in monoionized form.
(7) Adaptation to hypophosphite, however, led simultaneously to phosphite adaptation, so that these cells can utilize both P-compounds as a substitute for phosphate.
(8) The data show that detritylation and oxidation are side reactions which occur during the synthesis of monomeric units used in the construction of oligodeoxyribonucleotides by the phosphite triester method.
(9) It was shown that all 5'-phosphites effectively inhibit the production of viral antigens and protect cells from the cytotoxic effect of HIV infection.
(10) 2-(2-Pyridyl)ethyl group is a new type P-O protecting group for the synthesis of oligodeoxyribonucleotides by the phosphite triester method.
(11) Trimethyl and triethyl phosphites have general toxic effects.
(12) The naturally occurring DNA-nucleopeptide H-Asp-Ser[5'-pAAAGTAAGCC-3']-Glu-OH was prepared via a solid-phase phosphite triester approach using N-2-(tert-butyldiphenylsilyloxymethyl)benzoyl protected nucleosides.
(13) A gene coding for human stefin B was synthesized by the solid-phase phosphite method and cloned in the pUC8 cloning vector.
(14) Assays for phosphite removal by dilution or dialysis do not reverse the inhibition.
(15) The observed adaptation pattern, reflected by the alterations of phosphatase activity, was qualitatively equal with PO3-3 and PO3-2, but quantitatively different, because the response to hypophosphite gave much higher values than the increase obtained with phosphite.
(16) Data on the decreased toxicity of the phosphite mixture are explained from the viewpoint of a decreased pool disbalance of natural 2'-deoxynucleoside 5'-triphosphates in cells; a significant pool disbalance is developed in the case of 3'-azido-2',3'-dideoxythymidine action.
(17) Phosphonoacetaldehyde hydrolase inactivation by phosphite ion appears to be inconsistent with the concept of a Schiff base intermediate as proposed for Bacillus cereus enzyme.
(18) Reaction of 18 or 19 with triethyl phosphite gave, after deprotection, 6-(2,4-dichlorophenyl)-D-erythro-2,4-dihydroxyhexyl-phosphonic acid (5), and reaction of 19 with potassium cyanide gave, after subsequent hydrolysis and deprotection, 7-(2,4-dichlorophenyl)-D-erythro-3-hydroxy-5-heptanolide (3).
(19) Triphenyl phosphite (TPP)-induced delayed neurotoxicity, which is thought to resemble but somewhat differ from classical organophosphate-induced delayed neurotoxicity (OPIDN), is known to be age-dependent.
(20) Previous studies in mammals have found that exposure to triphenyl phosphite results in cellular and axonal degeneration in the spinal cord and medulla.
Radical
Definition:
(a.) Of or pertaining to the root; proceeding directly from the root.
(a.) Hence: Of or pertaining to the root or origin; reaching to the center, to the foundation, to the ultimate sources, to the principles, or the like; original; fundamental; thorough-going; unsparing; extreme; as, radical evils; radical reform; a radical party.
(a.) Belonging to, or proceeding from, the root of a plant; as, radical tubers or hairs.
(a.) Proceeding from a rootlike stem, or one which does not rise above the ground; as, the radical leaves of the dandelion and the sidesaddle flower.
(a.) Relating, or belonging, to the root, or ultimate source of derivation; as, a radical verbal form.
(a.) Of or pertaining to a radix or root; as, a radical quantity; a radical sign. See below.
(n.) A primitive word; a radix, root, or simple, underived, uncompounded word; an etymon.
(n.) A primitive letter; a letter that belongs to the radix.
(n.) One who advocates radical changes in government or social institutions, especially such changes as are intended to level class inequalities; -- opposed to conservative.
(n.) A characteristic, essential, and fundamental constituent of any compound; hence, sometimes, an atom.
(n.) Specifically, a group of two or more atoms, not completely saturated, which are so linked that their union implies certain properties, and are conveniently regarded as playing the part of a single atom; a residue; -- called also a compound radical. Cf. Residue.
(n.) A radical quantity. See under Radical, a.
(a.) A radical vessel. See under Radical, a.
Example Sentences:
(1) In conclusion, the efficacy of free tissue transfer in the treatment of osteomyelitis is geared mainly at enabling the surgeon to perform a wide radical debridement of infected and nonviable soft tissue and bone.
(2) The hypothesis that proteins are critical targets in free radical mediated cytolysis was tested using U937 mononuclear phagocytes as targets and iron together with hydrogen peroxide to generate radicals.
(3) These membrane perturbation effects not observed with bleomycin-iron in the presence of a hydroxyl radical scavenger, dimethyl thiourea, or a chelating agent, desferrioxamine, were correlated with the ability of the complex to generate highly reactive oxygen species.
(4) The role of O2 free radicals in the reduction of sarcolemmal Na+-K+-ATPase, which occurs during reperfusion of ischemic heart, was examined in isolated guinea pig heart using exogenous scavengers of O2 radicals and an inhibitor of xanthine oxidase.
(5) Flow cytometric DNA analysis was performed on both fresh and on paraffin embedded samples obtained by gastroscopic biopsies in 5 patients with histologically normal gastric mucosa (20 specimens) and by radical gastrectomies in 9 cases of human gastric cancer (36 specimens).
(7) Residual cancer was found in the radical prostatectomy specimen in 11 of the 29 stage-A1 patients (38%) and in 66 of the 86 stage-A2 patients (77%).
(8) This may be due to DMSO's ability to scavenge free radicals.
(9) A more radical surgery is recommended but with the limitation that the operative method must be adapted to the operative finding.
(10) The present study explored the possibility that SOD-mimics such as desferrioxamine-Mn(III) chelate [DF-Mn] or cyclic nitroxide stable free radicals could protect from O2-.-independent damage.
(11) Treatment modalities included: partial temporal bone resection, subtotal temporal bone resection, total temporal bone resection, radical mastoidectomy followed by radiation therapy, radiation therapy alone, and chemotherapy.
(12) Leaders of Tory local government are preparing radical proposals for minimum 10% cuts in public spending in the search for savings.
(13) Plays like The Workhouse Donkey (1963) and Armstrong's Last Goodnight (1964) were staged in major theatres, but as the decade progressed so his identification with the increasingly radical climate of the times began to lead away from the mainstream theatre.
(14) 78% of the recurrences were seen two years postoperatively and 27% were asymptomatic; 10% underwent radical operation, 27% palliative operation and 63% conservative treatment.
(15) The kinetics of bimolecular decay of alpha-tocopheroxyl free radicals (T) was studied by ESR mainly in ethanol and heptanol solvents.
(16) While the correlations between speed and accuracy reversed over time, the abnormal vision group began and ended at the most extreme levels, having undergone a significantly more radical shift in this regard.
(17) NPR reported that investigators have not found telltale signs associated with Islamist radicalization , such as a change in mosques or abrupt shifts in behavior or family associations.
(18) The second triplet, which was stable in the dark at 4.2 K following illumination, was assigned to the radical pair Donor+I-.
(19) It may be due to relative nonreactivity of ascorbic acid free radical that free radical chain reactions, found commonly in radical chemistry, do not occur in the scavenging reaction by ascorbic acid.
(20) The free radical scavengers mannitol, thiourea, benzoate, and 4-methylmercapto-2-oxobutyrate protected either native cells exposed to H2O2 or pretreated hepatocytes exposed to H2O2 and given ferric or ferrous iron.