(1) The incorporation of phosphine and phosphite ligands is described.
(2) In connection with this study, deoxyribonucleoside-3' dimethyl phosphites were synthesized and detailed properties of them are also described.
(3) The passive net transport of Li+ and Na+ across the human red cell membrane was accelerated by the divalent anions carbonate, sulphite, oxalate, phosphite and malonate.
(4) A period of adaptation was required prior to growth on phosphite when phosphate-grown cells were transferred to a medium containing a limiting amount of phosphate and excess phosphite.
(5) No phosphite-oxidizing activity could be detected in whole cells or cell-free extracts of phosphate-grown cells.
(6) The pH maxima observed for the phosphate analogs indicate a pK for this site of 5.5 at 37 degrees C. Intracellular pH changes associated with influx indicated that transport of the "fast" anion phosphite is largely in monoionized form.
(7) Adaptation to hypophosphite, however, led simultaneously to phosphite adaptation, so that these cells can utilize both P-compounds as a substitute for phosphate.
(8) The data show that detritylation and oxidation are side reactions which occur during the synthesis of monomeric units used in the construction of oligodeoxyribonucleotides by the phosphite triester method.
(9) It was shown that all 5'-phosphites effectively inhibit the production of viral antigens and protect cells from the cytotoxic effect of HIV infection.
(10) 2-(2-Pyridyl)ethyl group is a new type P-O protecting group for the synthesis of oligodeoxyribonucleotides by the phosphite triester method.
(11) Trimethyl and triethyl phosphites have general toxic effects.
(12) The naturally occurring DNA-nucleopeptide H-Asp-Ser[5'-pAAAGTAAGCC-3']-Glu-OH was prepared via a solid-phase phosphite triester approach using N-2-(tert-butyldiphenylsilyloxymethyl)benzoyl protected nucleosides.
(13) A gene coding for human stefin B was synthesized by the solid-phase phosphite method and cloned in the pUC8 cloning vector.
(14) Assays for phosphite removal by dilution or dialysis do not reverse the inhibition.
(15) The observed adaptation pattern, reflected by the alterations of phosphatase activity, was qualitatively equal with PO3-3 and PO3-2, but quantitatively different, because the response to hypophosphite gave much higher values than the increase obtained with phosphite.
(16) Data on the decreased toxicity of the phosphite mixture are explained from the viewpoint of a decreased pool disbalance of natural 2'-deoxynucleoside 5'-triphosphates in cells; a significant pool disbalance is developed in the case of 3'-azido-2',3'-dideoxythymidine action.
(17) Phosphonoacetaldehyde hydrolase inactivation by phosphite ion appears to be inconsistent with the concept of a Schiff base intermediate as proposed for Bacillus cereus enzyme.
(18) Reaction of 18 or 19 with triethyl phosphite gave, after deprotection, 6-(2,4-dichlorophenyl)-D-erythro-2,4-dihydroxyhexyl-phosphonic acid (5), and reaction of 19 with potassium cyanide gave, after subsequent hydrolysis and deprotection, 7-(2,4-dichlorophenyl)-D-erythro-3-hydroxy-5-heptanolide (3).
(19) Triphenyl phosphite (TPP)-induced delayed neurotoxicity, which is thought to resemble but somewhat differ from classical organophosphate-induced delayed neurotoxicity (OPIDN), is known to be age-dependent.
(20) Previous studies in mammals have found that exposure to triphenyl phosphite results in cellular and axonal degeneration in the spinal cord and medulla.
Trivalent
Definition:
(a.) Having a valence of three; capable of being combined with, substituted for, or compared with, three atoms of hydrogen; -- said of triad atoms or radicals; thus, nitrogen is trivalent in ammonia.
Example Sentences:
(1) Binding is inhibited by divalent and trivalent cations (Cd2+ and La3+ being most potent) and other calcium channel drugs (1,4 dihydropyridines, phenylalkylamines, benzothiazepines).
(2) Trivalent oral poliovaccine is used in Argentina to prevent poliomyelitis.
(3) The trivalent vaccine is intended to protect against currently circulating strains of influenza A(H3N2) and influenza B viruses and may provide partial protection against the new influenza A(H1N1) variant.
(4) The second tool is trivalent arsenical affinity chromatography, which we use to show novel direct interactions between trivalent arsenicals and several proteins from 3T3-L1 adipocytes including the insulin-responsive glucose transporter GLUT4, the insulin proreceptor, and both the alpha and beta subunits of tubulin.
(5) Trivalent oral attenuated poliovirus vaccine or enhanced potency inactivated vaccine administered at ages 4 and 12 months.
(6) The results of validation tests showed that both Cr(VI) and trivalent chromium, Cr(III), were stable in the collection medium and that samples may be stored for up to 100 days without appreciable loss of Cr(VI).
(7) The transmembrane potential of voltage-clamped squid giant axon is increased to compensate for a reduction in the rate of potassium channel kinetics when artificial seawater with trivalent erbium ion is substituted for artificial seawater.
(8) Antibody production in kwashiorkor and marasmic infants was studied by dividing them into three groups and giving the first group a single dose of trivalent live attenuated polio virus, the second group live attenuated measles virus and the third group diphtheriatoxoid.
(9) Circulating trivalent chromium can be taken up by tissues, and its distribution in the body depends on the species, age, and chemical form.
(10) Unfortunately, epidemiologic studies have not provided definitive answers to other questions: (i) does trivalent chromium present a cancer risk?
(11) The time course in the kidney suggests that this organ may be involved in the metabolism and elimination of trivalent chromium.
(12) The trivalent hybrid also was capable of priming T lymphocytes in vivo that responded to each of the native serotypes of M protein as well as to the synthetic hybrid peptide in vitro.
(13) At early pachytene, the 1;29 trivalent, although to a less extensive degree, was also unpaired in the pericentric region.
(14) Transitory neurological deterioration occurred in 38% of patients despite the early administration of trivalent (ABE) equine antitoxin.
(15) Riems FMD two-component oil emulsion vaccine was subcutaneously applied (5 ml) under field conditions to 855 store pigs of different age groups (trivalent--O1, A5, C).
(16) However, the higher seroconversion rates attained by using the inactivated trivalent influenza virus vaccine do not necessarily mean that it is more efficacious in preventing infection or severe illness or both due to natural wild-type influenza A virus.
(17) CSF-AK analysis indicated cerebral damage as absent or trival in 45%, moderate in 33% and marked in 22%.
(18) However, evidence was obtained from quantitative precipitation experiments which indicated that BPO(6)-lysine(7) functions as a trivalent hapten immunologically, i.e., capable of binding three antibody molecules per mole hapten.
(19) In an attempt to improve the serological response of infants in warm climates to oral poliovirus vaccine (OPV), the authors administered to 79 children between 6 and 41 weeks of age trivalent and monovalent OPV containing a virus dose 10 times as high as that found in the standard vaccine.
(20) Two of the chromosomes making up the trivalent were, most often, completely paired with each other and only partially paired or associated with the third one.