What's the difference between phthalimide and plastic?
Phthalimide
Definition:
(n.) An imido derivative of phthalic acid, obtained as a white crystalline substance, C6H4.(CO)2NH, which has itself (like succinimide) acid properties, and forms a series of salts. Cf. Imido acid, under Imido.
Example Sentences:
(1) 4,5-Bis(aminomethyl)acridine, useful as an immunosuppressant, was prepared in 31% overall yield by the reaction of acridine with N-(hydroxymethyl)phthalimide and subsequent decomposition with excess 6 N HCl.
(2) Structure-activity studies demonstrated the importance of the 5-ethyl, 6-methyl substituent pattern on the pyridinone ring and the need for a flexible two-atom linker between the pyridinone and phthalimide heterocycles.
(3) The use of small-bore glass columns packed with low liquid-phase-loaded insert supports has provided the capability for the separation and quantitative determination of a series of chloroethyl phthalimides.
(4) A series of cyclic imides, which possess a bulkier N-ring structure than phthalimide and saccharin, were shown to suppress LDL receptor binding, internalization and degradation of isolated rat hepatocytes, foam cells, human fibroblasts and mouse macrophages.
(5) Since at least one of the 2 cysteine residues in the C-subunit is known to be in close proximity to the interaction site between the C-subunit and the RII-subunit, these cysteines were chosen initially as targets for covalent modification by two heterobifunctional cross-linking reagents, p-azidophenacyl bromide and N-4-(azidophenylthio)phthalimide.
(6) According to both the electrophilic properties and the spatial requirements of the substituents, the effects were found to be up to 100 times stronger than those of thalidomide, and up to 10 times stronger than those of phthalimide respectively.
(7) Thirty-four young range cattle heavily infested with the common scabies mite, Psoroptes ovis, were dipped in phosmet (O,O-dimethyl phosphorodithioate S-ester with N-(mercaptomethyl)phthalimide) in 15 trials.
(8) The hypolipidemic agents, phthalimide, saccharin, o-(N-phthalimido) acetophenone, N-(p-chlorobenzoyl) sulfamate, and o-chlorobenzylsulfonamide affected low-density lipoprotein (LDL) and high-density lipoprotein (HDL) receptor activity and lipoprotein degradation.
(9) The synthetic sequence employed commercially available methyl p-hydroxybenzoate and n-(2,3-epoxypropyl)phthalimide as starting materials.
(10) The conversion of N-(hydroxymethyl)phthalimide (NHPH) to phthalimide could not be detected within 300 s at pH 9.0, whereas in 0.18 M NaOH complete conversion of NHPH to phthalimide was observed within 50 s. In the presence of 0.2-0.4 M 1,4-diazabicyclo[2.2.2]octane buffer solutions (pH 9.30-9.54), 40-60% conversion of NHPH to phthalimide occurred within 90-120 s. The initial concentration of NHPH affected the extent of conversion of NHPH to phthalimide.
(11) Reaction of 2,3,4,5,6-pentafluorobenzyl bromide with N-hydroxyphthalimide produced N-(2,3,4,5,6-pentafluorobenzyloxy)phthalimide which, after hydrazinolysis and treatment with hydrogen chloride, yielded O-(2,3,4,5,6-pentafluorobenzyl)hydroxylamine hydrochloride.
(12) Certain differences established between results of thin-layer chromatography, on the one hand, and 15N studies, on the other, are likely to support the assumption that phthalimide is further metabolised by splitting the imide ring yielding phthalamic acid.
(13) N-(omega-Aminoalkyl)-2,2,5,5-tetramethyl-3-pyrroline- or -pyrrolidine-3-carboxamides were acylated on the primary amino group of the side chain by means of reactive acid derivatives (acid chlorides, activated esters, phthalic anhydrides, phthalimide, 2-alkyl-4H-3,1-benzoxazin-4-ones) or they were alkylated by forming the Schiff bases and subsequent sodium borohydride reduction.
(14) Exploratory conversions of N-(omega-alkenyl)phthalimides failed to provide suitable precursors of the target compounds.
(15) A series of nitrogen substituted N-butan-3-one derivatives of cyclic imides (phthalimide, substituted phthalimide, o-benzosulfimide, 1,8-naphthalimide, 2,3-dihydrophthalazine-1,4-dione and diphenimide) and their semicarbazone, thiosemicarbazone and acethydrazone derivatives were investigated for hypolipidemic activity in rodents.
(16) These N-substitutions afforded no improvement over other known N-substitutions (e.g., butyl, 3-butanone, or the propionic acid derivatives of phthalimide, saccharin, and 2,3-dihydrophthalazine-1,4-dione) compared with the respective parent compounds.
(17) The chromatographic behaviour of phthalimide derivatives during thin-layer chromatography on silica gel is explained by the repercussions of mesomeric and inductive effects on the specific combined action of the oxygen of the carbonyl groups and of protonized hydrogen atoms of the active centres on the surface of the adsorbent.
(18) In contrast, the C-subunit modified by N-4-(azidophenylthio)phthalimide was cross-linked to the RII-subunit by a mechanism that was independent of photolysis.
(19) The N-(1-chloroethyl) phthalimide compound is not stable even in thisinert system, but it can be stabilized by the room temperature preparation of the N-(1-ethoxyethyl) phthalimide derivative.
(20) Compounds such as N-(2-chlorovinyl) and N-(1,2-DICHLOROETHYL) PHTHALIMIDE HAVE BEEN MEASURED WITH A RELATIVE STANDARD DEVIATION OF NO MORE THAN 1.4%.
Plastic
Definition:
(a.) Having the power to give form or fashion to a mass of matter; as, the plastic hand of the Creator.
(a.) Capable of being molded, formed, or modeled, as clay or plaster; -- used also figuratively; as, the plastic mind of a child.
(a.) Pertaining or appropriate to, or characteristic of, molding or modeling; produced by, or appearing as if produced by, molding or modeling; -- said of sculpture and the kindred arts, in distinction from painting and the graphic arts.
Example Sentences:
(1) The various evocational changes appear to form sets of interconnected systems and this complex network seems to embody some plasticity since it has been possible to suppress experimentally some of the most universal evocational events or alter their temporal order without impairing evocation itself.
(2) With the exception of PMMA and PTFE, all plastics leave a very heavy tar- and soot deposit after burning.
(3) The consequences of proved hypersensitivity in patients with metal-to-plastic prostheses, either present prior to insertion of the prosthesis or evoked by the implant material, are not known.
(4) We found that when neutrophils were allowed to settle into protein-coated surfaces the amount of O2- they generated varied with the nature of the protein: IgG greater than bovine serum albumin greater than plastic greater than gelatin greater than serum greater than collagen.
(5) FGF did not influence P production, while EGF clearly increased basal P production of the cells cultured on plastic.
(6) Alveolar macrophages (greater than 97% esterase positive) were isolated form bronchoalveolar lavage fluids by adherence onto plastic.
(7) During collection, the rat was restrained in a plastic holder where it was free to eat.
(8) The agency, which works to reduce food waste and plastic bag use, has already been gutted , with its budget reduced to £17.9m in 2014, down from £37.7m in 2011.
(9) Radiological examination provides more accurate indications for plastic surgery of the pelvic floor, influences the operative procedures and permits better evaluation of operative results.
(10) Unlike cells grown on plastic, RME cells grown on type I collagen were readily subculturable and serial subculture resulted in the cells undergoing 15-20 population doublings (5-6 passages) before exhibiting any loss of growth potential.
(11) In 36 patients plastic reconstruction of the urinary bladder, sphincter and urethra was performed with local tissues after the Young technic in the G. A. Bairov modification.
(12) This result contraindicates a general permissive-requisite role for forebrain NE for the mammalian brain's plasticity during its critical periods.
(13) Markram's papers on synaptic plasticity and the microcircuitry of the neural cortex were enough to earn him a full professorship at the age of 40, but his discoveries left him restless and dissatisfied.
(14) Thus functional plasticity in response to early experience appears to be a fundamental aspect of cortical development.
(15) A metal-plastic prosthesis was tested in positions and with forces considered applicable to arthritics.
(16) The surgeon must have an exact idea of this canal before undertaking operation for plastics of the hernial defect.
(17) HVc and RA grow during the subsong and plastic song periods of song development.
(18) Asymmetries occur less often whilst using the low-cervical-pull according to Sander, due to the reduced friction between the two plastic parts of this headgear system.
(19) This paper reports the findings of a national survey of Medical Schools and Plastic Surgery Units.
(20) Plastic surgery seems to be successful in mitral valve lesions, whereas lesions of the aortic valve are such that valve replacement is required.