(a.) Of or pertaining to physiology; relating to the science of the functions of living organism; as, physiological botany or chemistry.
Example Sentences:
(1) We have investigated a physiological role of endogenous insulin on exocrine pancreatic secretion stimulated by a liquid meal as well as exogenous secretin and cholecystokinin octapeptide (CCK-8) in conscious rats.
(2) The stages of mourning involve cognitive learning of the reality of the loss; behaviours associated with mourning, such as searching, embody unlearning by extinction; finally, physiological concomitants of grief may influence unlearning by direct effects on neurotransmitters or neurohormones, such as cortisol, ACTH, or norepinephrine.
(3) Results suggest that Cd-MT is reabsorbed and broken down by kidney tubule cells in a physiological manner with possible subsequent release of the toxic cadmium ion.
(4) Nucleotide, which is essential for catalysis, greatly enhances the binding of IpOHA by the reductoisomerase, with NADPH (normally present during the enzyme's rearrangement step, i.e., conversion of a beta-keto acid into an alpha-keto acid, in either the forward or reverse physiological reactions) being more effective than NADP.
(5) This suggests that a physiological mechanism exists which can increase the barrier pressure to gastrooesophageal reflux during periods of active secretion of the stomach, as occurs in digestion.
(6) The effects of H1 and H2 antihistamines on a variety of physiological vasodilator responses were examined.
(7) A good understanding of upper gastrointestinal physiology is required to properly understand the pathophysiological events in various diseases or after operations on the upper gastrointestinal tract.
(8) This pattern was not seen for other physiologically active amino acids.
(9) These results suggest that aluminum is able to gain access to the central nervous system under normal physiological conditions.
(10) The physiological importance of this inhibition is discussed.
(11) The morphology and physiology of the large adapting unit (LAU: Fig.
(12) The use of 100% oxygen to calculate intrapulmonary shunting in patients on PEEP is misleading in both physiological and methodological terms.
(13) Considerable glucose 6-phosphatase activity survived 240min of treatment with phospholipase C at 5 degrees C, but in the absence of substrate or at physiological glucose 6-phosphate concentrations the delipidated enzyme was completely inactivated within 10min at 37 degrees C. However, 80mM-glucose 6-phosphate stabilized it and phospholipid dispersions substantially restored thermal stability.
(14) These results are consistent with a possible physiological role for medullary TRH in the vagal regulation of gastric contractility.
(15) The cells were taken from cultures in low-density balanced exponential growth, and the experiments were performed quickly so that the bacteria were in a uniform physiological state at the time of measurement.
(16) Atrioventricular (AV) delay that results in maximum ventricular filling and physiological mechanisms that govern dependence of filling on timing of atrial systole were studied by combining computer experiments with experiments in the anesthetized dog instrumented to measure phasic mitral flow.
(17) At physiologic doses (10(-8) M) estradiol inhibits the binding at a significant extent on the soluble receptor, but not on membrane-bound form.
(18) With the successful culture of these tissues, their development, biochemistry, and physiology, potentially of great importance in understanding early vertebrate evolution, can be better understood.
(19) The binding follows the principle of isotope dilution in the physiologic range of vitamin B12 present in human serum.
(20) Axonal regeneration with the ANG was equal to SAGs as measured by axonal diameters, physiological, and functional methods, although the SAG demonstrated statistically higher axonal counts.
Zymogene
Definition:
(n.) One of a physiological group of globular bacteria which produces fermentations of diverse nature; -- distinguished from pathogene.
Example Sentences:
(1) The study confirms that secretin influences pancreatic protein secretion and indicates in addition, that pharmacologic doses of the hormone, have the capacity to block acinar cell zymogen granule release.
(2) The data indicate that collagenase is released from the cells in inactive form, as a zymogen.
(3) Thus it can be tentatively suggested that it is prokallikrein A which is secreted into the pancreatic juice and represents the physiologically important zymogen.
(4) The presence of acinar cells with zymogen granules, squamous metaplasia and endocrine components makes the diagnosis.
(5) The cDNA-inferred amino acid sequence of apo[a] indicates that apo[a], like plasminogen and some zymogens, is composed of a kringle domain and a serine protease domain.
(6) When aprotinin was added during the course of the purification, the major species isolated was the zymogen form (28,000 Da) of pump-1.
(7) At very low detergent concentrations, below the critical micelle concentration, the anionic sulfates induce protein aggregation such that phospholipase A2, as well as its zymogen, is present in high molecular weight complexes containing several protein molecules.
(8) We combined these changes with a genetically altered glycoform to generate a zymogen protein C with a 60-fold increased cleavage rate by free alpha-thrombin, independent of its cofactor thrombomodulin.
(9) During autoactivation in a cell-free system, the 55 and 53 kDa zymogens are sequentially converted into the 49, 36, 31 and 25 kDa forms.
(10) Human C'1, a macromolecular complex composed of three subunits, is the zymogen for at least two distinct enzymes.
(11) Combination therapy with E-3123 and CMZ showed significant protective effects against the high mortality rate, increased serum amylase and ascitic fluid amylase levels, pancreatic amylase and lysosomal enzyme content, plasma endotoxin levels, redistribution of lysosomal enzyme from the lysosomal to the zymogen fraction, lysosomal and mitochondrial fragility, and also improved the histological findings when compared with the E-3123 alone.
(12) The circulating zymogen form of thrombin, prothrombin, was converted to proteolytically active thrombin during incubation with ECM.
(13) In the three groups of animals, lipase antigenic sites were detected with high resolution in the acinar cells in the compartments involved in protein secretion: rough endoplasmic reticulum, Golgi apparatus, and secretory zymogen granules.
(14) The overall identity with other zymogens for gastric proteinases is 27%.
(15) The fusion of granules with plasma membranes was unaffected by variation of the Ca2+ concentration over a wide range, but fusion of granules with both plasma membranes and zymogen granule membranes was stimulated by GTP and, more potently, by guanosine 5'-[gamma-thio]triphosphate (GTP[S]).
(16) Notably, zymogen granule dissolution neither preceded nor accompanied this swelling, but developed pari passu with cell degradation.
(17) We found small amounts of lysosomal enzymes colocalized with digestive enzymes within zymogen granules in normal acinar cells and in normal pancreatic juice, suggesting some physiological roles of lysosomal enzymes in pancreatic ducts.
(18) Both tumor cells frequently contained well-developed RER, zymogen-like granules, and annulate lamellae.
(19) For the native zymogen the rate of this conversion had been shown to be identical to the rate of cleavage of the scissile bond of pepsinogen.
(20) Ala-neochymotrypsinogen was activated by incubating with trypsin at a zymogen : trypsin ratio of 30 : 1 in 0.1 M phosphate buffer, pH 7.6 at 4 degrees C for 1 h. The fully active, stable species was identified as alpha-chymotrypsin.