(n.) A deposition, esp. an excessive deposition, of coloring matter; as, pigmentation of the liver.
Example Sentences:
(1) The results also suggest that the dispersed condition of pigment in the melanophores represents the "resting state" of the melanophores when they are under no stimulation.
(2) Differences between the albino vs pigmented strains were observed following injections of saline.
(3) Two lectins, wheat germ agglutinin (WGA) and peanut agglutinin (PNA), were used to compare domains within the interphotoreceptor matrices (IPM) of the cat and monkey, two species where the morphological relationship between the retinal pigment epithelium (RPE) and photoreceptors is distinctly different.
(4) Uptake studies with 22Na were performed in cultured bovine pigmented ciliary epithelial cells, in order to characterize mechanisms of Na+ transport.
(5) CW Nd:YAG light transmitted by fiber optic cable and sapphire crystal was applied transsclerally to the ciliary body of pigmented and albino rabbits.
(6) The evolution and function of multiple forms of a given photosynthetic pigment in vivo are discussed.
(7) Changes in protein phosphorylation induced by phagocytic challenge were identified in cultured rat retinal pigment epithelium (RPE) following exposure to isolated rat rod outer segments (ROS) or to polystyrene latex microspheres (PSL).
(8) Both categories frequently showed pellagrous pigmentation and mucocutaneous signs of B-vitamin deficiency.
(9) We show that, in digitonin-permeabilized goldfish xanthophores, the pigment organelles can be induced to disperse by a combination of cAMP, ATP, and xanthophore cytosol.
(10) A red pigment produced by the actinomycete strain B 4358 was identified as butyl-meta-cycloheptylprodiginine (4) by 1H, 13C and correlation via long range coupling NMR spectra.
(11) Two unusual types of oral mucosal pigmentation are reported.
(12) These results are consistent with the idea that RPE pigment dispersion is triggered by a substance that diffuses from the retina at light onset.
(13) Rhabdomeres are substantially smaller and visual pigment is nearly eliminated when Drosophila are carotenoid-deprived from egg to adult.
(14) It is hypothesized that deposition of bilirubin in tissues takes place as an ongoing event, the deposited pigment being eliminated by bilirubin oxidase in healthy infants.
(15) The calculated separation between the centers of these two pigments (using an extended version of the exciton theory) is about 10 A, the pigments' molecular planes are tilted by about 20 degrees, and their N1-N3 axes are rotated by 150 degrees relative to each other.
(16) We have investigated enhancement of pigmentation in inbred C3H- mice using tail skin as a model for testing the effects of phosphorylated DOPA (DP) and ultraviolet radiation.
(17) Although mucocutaneous pigmentation was not present in two of the three patients, the features of intestinal polyposis are consistent with those of Peutz-Jeghers syndrome.
(18) Cytochromes b, c(555), possibly c(1), cytochrome oxidase, a carbon monoxide-binding pigment, and flavoproteins were detectable in the spectra of both intact cells and mitochondria.
(19) The addition of alcohol to the drinking-water resulted in the formation of stones rich in pigment.
(20) The total number of neuronal cell bodies was 25% lower in AIDS (P less than 0.01) than in 12 age-matched controls, although the volume density of neuronal melanin did not differ from that of controls because the percentage of pigmented cell bodies was higher (P less than 0.01) and the cell bodies were more fully packed with melanin in AIDS.
Vitiligo
Definition:
(n.) A rare skin disease consisting in the development of smooth, milk-white spots upon various parts of the body.
Example Sentences:
(1) Six patients with spreading vitiligo treated with applications of monobenzone developed a vesicular dermatitis.
(2) Duplicate heparinized blood samples were drawn from 22 subjects; 2 healthy subjects, 1 vitiligo and 19 with thyroid or parathyroid diseases.
(3) Jackson said he suffered from vitiligo, a condition that causes the skin to lose its pigment.
(4) Three patients with malignant melanoma and coexisting vitiligo are described.
(5) Two vitiligo patients were hypergastrinaemic suggesting latent pernicious anaemia.
(6) The psoralen analogs 8-methoxypsoralen (8-MOP) and 4,5',8-trimethylpsoralen (TMP), in combination with ultraviolet light (UVA, 320-400 nm), are potent modulators of epidermal cell growth and differentiation and are commonly used in photochemotherapy of psoriasis and vitiligo.
(7) Since persons with the Down syndrome are predisposed to immunological deficiency in thymus-dependent (T-cell) function, findings from the skin examinations suggest that immunologic factors might contribute to the increased incidence of vitiligo and alopecia areata seen in the Down syndrome.
(8) Association with diseases such as diabetes, vitiligo and hypothyroidism have strengthened the auto-immune nature of this syndrome.
(9) The results of the present study suggest that systemic factors may play a role in the pathogenesis of vitiligo and acquired hypomelanosis guttata.
(10) Psycho- and autonomotropic drugs, acupuncture, and psychotherapeutic conversations were used for the correction of psychologic abnormalities in 49 vitiligo patients, presenting with impaired sociopsychological adaptation and autonomic imbalance.
(11) The data obtained suggest that kynurenine and serotonin pathways of tryptophan metabolism were intensified in vitiligo.
(12) The lysis of human melanocytes by vitiligo patients' sera by two different effector mechanisms provides direct support for the autoimmune hypothesis of human vitiligo.
(13) No significant differences in the results of several immunological examinations (E-RFC, EAC-RFC, EA-RFC, IF, IF-elution) came to light results suggest that the lymphocytes are probably not implied in the pathogenesisof vitiligo.
(14) In three men vitiligo-like skin changes, enlargement of liver and spleen and diffuse goitre (grade II) with increased TSH secretion developed within one to two years of their having started work in a factory producing paratertiary butylphenol.
(15) Vitiligo lesions themselves gave rise to unidentified dendritic cells that survived for 10-15 days without manifesting any growth.
(16) C4 typing by Western blot analysis showed the frequency of the C4A*Q0 allele in the vitiligo patient group to be close to normal.
(17) This culture system will be applied to investigate the basic pathophysiology of vitiligo and other various pigmentary dermatoses.
(18) Vitiliginous achromia with malignant melanoma shows some discrepancies with vitiligo.
(19) A 45 year old Saudi male with poliosis, alopecia areata, vitiligo, anterior uveitis, inflammatory changes in the posterior pole of the retina and paraparesis presented with features of the Vogt-Koyanagi-Harada syndrome, uncontrolled diabetes mellitus and hypothyroidism.
(20) A diabetic patient is described presenting psoriasis, necrobiosis lipoidica diabeticorum, granuloma annulare, and vitiligo and with a history of recurrent erysipelas and mycotic infections.