(n.) A fixed pin or short axis, on the end of which a wheel or other body turns.
(n.) The end of a shaft or arbor which rests and turns in a support; as, the pivot of an arbor in a watch.
(n.) Hence, figuratively: A turning point or condition; that on which important results depend; as, the pivot of an enterprise.
(n.) The officer or soldier who simply turns in his place whike the company or line moves around him in wheeling; -- called also pivot man.
(v. t.) To place on a pivot.
Example Sentences:
(1) Excessive accumulation of hydrogen ions in the brain may play a pivotal role in initiating the necrosis seen in infarction and following hyperglycemic augmentation of ischemic brain damage.
(2) The function of motherese has become a pivotal issue in the language-learning literature.
(3) Glucose is the principal source for energy production in the brain, and undisturbed glucose metabolism is pivotally significant for normal function of this organ.
(4) Currently employed clinical indicators of perfusion provide inadequate warning of developing hazards caused by marginal perfusion in certain vital organs or "peripheral" tissues that are pivotal to postsurgical wound healing.
(5) Endobronchial biopsy and bronchial lavage studies following inhaled PAF did not show any increase in the number of activation of eosinophils, which are pivotal in the pathogenesis of BHR.
(6) Turkish police have stormed the offices of an opposition media group days before the country’s pivotal election, in a crackdown on companies linked to a US-based cleric and critic of President Recep Tayyip Erdoğan .
(7) It was the introduction of Aluko that proved pivotal.
(8) This article discusses the effect of existing statutes and case law on three pivotal questions: To what sort of information are people entitled?
(9) It has been generally accepted that the deregulation of oncogenes or their regulators play a pivotal role in progression of this prevalent disease.
(10) The fact that Fraser suggested Pinter write one of the pivotal scenes, in which Emma challenges Jerry to leave his wife, was a revelation, he says.
(11) Marine Rotational Force – Darwin” (MRF-D) is one of four American marine air ground task forces (MAGTFs) in the Asia-Pacific region, along with those in Guam, Hawaii and Okinawa, the sum of which make up a central strategic pillar of the pivot.
(12) Facebook Twitter Pinterest ‘I’m president, they’re not’: Donald Trump at rally in Washington Trump is “much more resilient” than his opponents allow, said Newt Gingrich, the former House speaker, before pivoting to a plug for his new book, Understanding Trump .
(13) Twitter has become pivotal in organising anti-government dissent in the past year: the Occupy Gezi movement, which marches against the recently passed internet censorship bill that allows the government to block any content within four hours without a court order, and the massive street protest and the funeral attended by hundreds of thousands after the death of 15-year-old Berkin Elvan , were initiated via social media.
(14) Verbal and non verbal communication skills (with the patient and the team) are pivotal in this approach; relatives are considered partners in the care of the patient and an essential element of the caring environment.
(15) This year will mark the start of a pivotal chapter for development as the UN finalises ambitious goals this autumn to improve all lives and secure a healthy planet.
(16) The 5' cap structure of eucaryotic mRNA plays a pivotal role in mRNA metabolism.
(17) Thirty years after one of the pivotal clashes in the miners' strike of 1984 when violent confrontations erupted at the Orgreave coking plant, the area outside Sheffield could barely look more different.
(18) Arthritic symptoms were present at operation in thirty patients, while thirty-four had no postoperative objective signs of pivot shift or instability.
(19) Two lines of evidence indicate that the general transcription factor TFIIB is a pivotal component in the mechanism by which an acidic activator functions.
(20) If cortical actin filaments are disrupted with dihydrocytochalasin B, processes form that are similar to those induced by dBcAMP suggesting that the disruption of the cortical actin network is the pivotal step in process formation.
Potence
Definition:
(n.) Potency; capacity.
Example Sentences:
(1) A total of 104 evaluable patients 20-90 years old treated by direct vision internal urethrotomy a.m. Sachse for urethral strictures reported retrospectively via a questionnaire their sexual potency before and after internal urethrotomy.
(2) Estimates of potential for gastrointestinal side effects using the rat enteropooling assay and in vivo monkey effects indicate that diarrhea will be substantially reduced with retention of uterine stimulating potency.
(3) The relative potencies compared to insulin-like growth factor 2 (IGF-2) in displacing [125I]IGF-2 from rat liver membranes were recombinant truncated IGF-1, 0.3% and recombinant IGF-1, 0.2%.
(4) Thus, introduction of arginine in position 5 with a hydrophobic amino acid in position 6 is compatible with high potency in several biological systems and results in compounds with lowered potency to release histamine compared to homologous peptides with tyrosine in position 5 and D-arginine in position 6.
(5) Significant differences in the pharmacological characteristics of the alpha 2 adrenoceptor were observed between the tissues with reference to both absolute drug affinities as well as rank order of drug potency.
(6) We investigated the in vivo phospholipidosis-inducing potency of AM and its major nonpolar metabolite, desethylamiodarone (DEA), in rats, their ability to inhibit phospholipases, and also the effects on pulmonary uptake of [14C] AM.
(7) This activity scheme uses as its base, dose potency measured as TD50, the chronic dose rate that actuarially halves the adjusted percentage of tumor-free animals at the end of the study (Gold et al., Environ.
(8) Neuropeptides increased the labeling of p115 within seconds and with great potency; half-maximum concentrations were 0.1, 0.2 and 0.3 nM for bombesin, vasopressin, and VIC, respectively.
(9) The rank order of potency of the peptides tested was VIP greater than rat (r) peptide histidine isoleucine = human (h) PHI greater than rGRF greater than bovine GRF = porcine PHI = VIP-(10-28) greater than hGRF greater than secretin greater than apamin greater than glucagon.
(10) Unlabeled IGF-I displaced both the IGF-I and insulin bindings with potencies that were 100 and 10 times as great as insulin.
(11) Displacing potencies for dopamine in the nanomolar range are associated with agonist-specific D-3 receptor binding and it is predicted that the component of D-2 binding with high agonist affinity may play a confounding role in many D-3 receptor studies.
(12) Menses resumed in all 6 women 7 to 41 days after the injection, galactorrhea disappeared in all 4 patients, and libido and potency become normal in both men with microprolactinomas.
(13) A hybrid analog cecropin A-(1-11) D-(12-37) was designed and predicted to have enhanced potency.
(14) On guinea-pig lung strip the rank order of potency was U-46619 greater than Wy17186 much greater than PGF2 alpha greater than PGE2 and responses to all agonists tested were blocked by AH19437 but not by SC-19220.
(15) Quantitatively, however, there was not a good correlation between liver DNA alkylation and the potency of the nitrosamine in inducing tumors.
(16) On the other hand, SM-3997 and buspirone exhibited dopamine antagonistic action, although the potency of SM-3997 was less than one fourth that of buspirone.
(17) The wide variation in potency explains the variation found in absolute bioavailability, and the increase in release rate when the pellets are crushed explains the differences seen in peak plasma times, since the pellets will be chewed to varying degrees by the horse.
(18) Comparing IC50 values of EGCG and aspirin it was found that the potency of EGCG is comparable to that of aspirin.
(19) Hyperprolactinemia, hypogonadotropinism, and subnormal plasma testosterone were found in a 65-year-old patient who had an enlarged sella turcica, complained of fatigue, and addmitted to decreased sexual interest and potency.
(20) The present study attempts to relate this inhibitory effect to the vasoconstrictive potency of ADH.