(n.) That which smites, wounds, or troubles; a blow; a calamity; any afflictive evil or torment; a great trail or vexation.
(n.) An acute malignant contagious fever, that often prevails in Egypt, Syria, and Turkey, and has at times visited the large cities of Europe with frightful mortality; hence, any pestilence; as, the great London plague.
(v. t.) To infest or afflict with disease, calamity, or natural evil of any kind.
(v. t.) Fig.: To vex; to tease; to harass.
Example Sentences:
(1) In contrast, uncloned NJ12508 stock virus killed 1 of 24 hens and FL27716 stock virus killed 4 of 24 hens, and neither produced the complete spectrum of lesions associated with fowl plague.
(2) The Semliki Forest virus spike subunit E2, a membrane-spanning protein, was transported to the plasma membrane in BHK cells after its carboxy terminus, including the intramembranous and cytoplasmic portions, was replaced by respective fragments of either the vesicular stomatitis virus glycoprotein or the fowl plague virus hemagglutinin.
(3) Thus, has been shown a leading role of transmission of plague microbe by fleas in the maintenance of natural nidality of this zoonosis.
(4) The adsorption capacity of microgranulated polyacrylamide magnetic immunosorbents has been studied by the method of quantitative immunofluorescence as applied to the causative agents of plague, cholera, and melioidosis.
(5) Processing of plague plasminogen activator (p36 to p33), responsible for hydrolysis of Yops, required 2 h. Avirulence of mutants with inserted Mu dl1 (Apr lac) in yopE was verified and shown to occur independently of introduced fusion-dependent peptides.
(6) Their creation in 2006 marked a turning point in stem cell research , because iPS cells suffer from none of the ethical issues that plague embryonic stem cells.
(7) Like domestic animals, the latter died of hunger probably, any corpse or carcass being considered as plague victims.
(8) Attention is focused on the Railways' campaigns against malaria, plague and infectious diseases.
(9) He is an expert on the public health problems that plague El Paso and the other cities along the international border, all of which are exacerbated by abject poverty and a burgeoning population.
(10) Hollowing out legacy media’s revenues while using its content, “ digital colonialism ” and issues of censorship have plagued the company in 2016.
(11) Plagued by prison riots, IRA breakouts, illegal deportations, verdicts that found him in contempt of court, and over-hasty legislation on dogs, he acquired a reputation – as home secretaries often do – for being accident-prone.
(12) In the natural foci of plague and tularemia, as well as on the territories outside such foci, the causative agents of intestinal yersiniosis, pseudotuberculosis, salmonellosis, erysipeloid, staphylococci and streptococci, arena- and arboviruses have been isolated from the rodents and ectoparasites under study.
(13) The infection, confirmed by viral culture, was produced by Dutch strain (Hav 1 Neq 1) of fowl plague virus.
(14) The lytic activity of plague phage II, serovar 3, with respect to 1,800 bacterial strains has been studied: 760 Yersinia pestis strains, 262 Y. pseudotuberculosis strains, 252 Y. enterocolitica strains, 166 Escherichia coli strains, 90 Shigella strains and 270 strains of other species.
(15) Scottish Natural Heritage is exterminating them in the Outer Hebrides not because there is a plague of hedgehogs there but to protect the nests of the wading birds whose eggs and chicks a few escaped pet hedgehogs having been eating.
(16) The sera from plague patients recognized Y. pestis and Y. enterocolitica antigens ranging from 15 to 72 kilodaltons (kDa), whereas sera from immunized subjects recognized four antigenic components in Y. pestis ranging from 17 to 64 kDa and five antigens in Y. enterocolitica ranging from 16 to 68 kDa.
(17) But the project has been plagued by cost problems since it was first mooted under the last Labour government.
(18) Mourinho’s interest in Gomes and Jõao Mário suggests Bastian Schweinsteiger, who has suffered an injury-plagued first season at United and who is 32 in August, may be under threat.
(19) You’ve plagued her life and the life of her family.” Maitlis was not in court for the sentencing.
(20) In South Sudan, where civil war broke out a year ago, 1.5 million people are severely food insecure, while the sectarian violence that has plagued CAR since March has left a quarter of the population – more than 1 million people – displaced within its borders or in neighbouring countries.
Virus
Definition:
(v. i.) Contagious or poisonous matter, as of specific ulcers, the bite of snakes, etc.; -- applied to organic poisons.
(v. i.) The special contagion, inappreciable to the senses and acting in exceedingly minute quantities, by which a disease is introduced into the organism and maintained there.
(v. i.) Fig.: Any morbid corrupting quality in intellectual or moral conditions; something that poisons the mind or the soul; as, the virus of obscene books.
Example Sentences:
(1) Herpesviruses such as EBV, HSV, and human herpes virus-6 (HHV-6) have a marked tropism for cells of the immune system and therefore infection by these viruses may result in alterations of immune functions, leading at times to a state of immunosuppression.
(2) These results show that the pathogenic phenotypes of MCF viruses are dissociable from the thymotropic phenotype and depend, at least in part, upon the enhancer sequences.
(3) It is quite interesting to analyse which gene of the virus determines the characteristics of the virus.
(4) The extent of the infectious process was limited, however, because the life span of the cultures was not significantly shortened, the yields of infectious virus per immunofluorescent cell were at all times low, and most infected cells contained only a few well-delineated small masses of antigen, suggestive of an abortive infection.
(5) The promoters of the adenovirus 2 major late gene, the mouse beta-globin gene, the mouse immunoglobulin VH gene and the LTR of the human T-lymphotropic retrovirus type I were tested for their transcription activities in cell-free extracts of four cell lines; HeLa, CESS (Epstein-Barr virus-transformed human B cell line), MT-1 (HTLV-I-infected human T cell line without viral protein synthesis), and MT-2 (HTLV-I-infected human T cell line producing viral proteins).
(6) It was also able to inhibit the binding both of alpha-bungarotoxin and rabies virus glycoprotein to the acetylcholine receptor.
(7) Subtypes of HBs Ag are already of great use in the epidemiology of hepatitis B virus infections; yet they may have additional significance.
(8) PMN were found to be nonpermissive for HSV replication and were unable to bind virus in the absence of antibody.
(9) Analysis revealed some significant differences in the false-positive rate, depending on the test method used or virus samples evaluated.
(10) The transported pIgA was functional, as evidenced by its ability to bind to virus in an ELISA assay and to protect nonimmune mice against intranasal infection with H1N1 but not H3N2 influenza virus.
(11) The p60v-src protein encoded by Prague Rous sarcoma virus was found to contain two sites of tyrosine phosphorylation.
(12) Other research has indicated that placing gossypol in the vagina does inhibit the effect of herpes simplex virus type 2 infection, however.
(13) The causative organisms included viruses, fungi, and bacteria of both high and low pathogenicity.
(14) The antiproliferative activity of IFN was studied using the parental L cell line, a tk- derivative, and a tk- (tk+) subline into which the tk gene of herpes simplex virus was introduced.
(15) It could be demonstrated by radioimmune precipitation of virus labeled with[35S]methionine that all three polypeptides are specific for hog cholera virions.
(16) Hyperimmunization with the tick encephalitis and Western horse encephalomyelitis viruses reproduced in the brain of albino mice, intensified the protein synthesis in the splenic tissue during the productive phase of the immunogenesis (the 7th day).
(17) No cross reactions were found between bluetongue and epizootic haemorrhagic disease of deer viruses.
(18) Cytolytic T lymphocytes lysing virus-infected and uninfected myocytes and heart-reactive autoantibodies occur in both myocarditis-susceptible strains.
(19) Whole-virus vaccines prepared by Merck Sharp and Dohme (West Point, Pa.) and Merrell-National Laboratories (Cincinnati, Ohio) and subunit vaccines prepared by Parke, Davis and Company (Detroit, Mich.) and Wyeth Laboratories (Philadelphia, Pa.) were given intramuscularly in concentrations of 800, 400, or 200 chick cell-agglutinating units per dose.
(20) We have recently described a nonnucleoside compound that specifically inhibits the reverse transcriptase of human immunodeficiency virus type 1 (HIV-1), the causative agent of AIDS.