What's the difference between plasmin and plastin?
Plasmin
Definition:
(n.) A proteid body, separated by some physiologists from blood plasma. It is probably identical with fibrinogen.
Example Sentences:
(1) Increased plasmin activity was associated with advancing stage of lactation and older cows after appropriate adjustments were made for the effects of milk yield and SCC.
(2) Lp(a) also complexes to plasmin-fibrinogen digests, and binding increases in proportion to the time of plasmin-induced fibrinogen degradation.
(3) Plasmin-alpha 2-antiplasmin complex was not detected in any of the subjects after venous occlusion.
(4) Zona pellucida solubility, plasminogen activator production, and plasminogen conversion to plasmin increased as embryonic stage advanced; however, plasminogen activator production and plasmin conversion to plasmin were poorly correlated with zona pellucida solubility.
(5) In the alpha 2M-thrombin, alpha 2M-plasmin, and alpha 2M-trypsin complexes, approximately 50%, 60%, and 75% of the subunits are cleaved, respectively.
(6) In testing the hypothesis that Lp(a) can competitively inhibit plasma clot lysis mediated by plasmin, the present study shows that Lp(a) significantly enhanced plasma clot lysis mediated by streptokinase or t-PA.
(7) The activity was not due to plasmin, contact activation, or coagulation factors, since it was fully generated in plasminogen-depleted, factors XII, XI, VII deficient, and prekallikrein-deficient plasmas.
(8) We present evidence that over-expression of human plasminogen, the precursor to the serine protease plasmin, can be cytotoxic to mammalian cells.
(9) These plasmin-cleaved peptides are derived from the COOH terminus of C2b, and they induce the contraction of estrous rat uterus.
(10) One factor that may influence the lipid deposition is immobilization of part of the LDL in lesions, and an immobilized fraction can be released by incubation with the fibrinolytic enzyme, plasmin, suggesting that it is associated with fibrin.
(11) The MTX peptides were not hydrolyzed by a variety of proteolytic enzymes (e.g., trypsin, plasmin, urokinase, aminopeptidase).
(12) Plasmin and elastase may play mutual roles in thrombolysis, inflammation, and tumour invasion and metastasis.
(13) In addition to generating a chemotactic factor, plasmin destroys the complement-associated chemotactic factor that is a trimolecular complex consisting of the fifth (C'5), sixth (C'6), and seventh (C'7) components of complement.
(14) These results suggest that simultaneous measurements of XDP and plasmin-alpha 2PI complex in plasma would be valuable for the pharmacological or hemostatic assessment of thrombolytic therapy.
(15) The difference in the activator activities of plasmins from various animal sources in complex with streptokinase therefore might be due to the difference in the compositions of light chains of plasmins.
(16) The human alpha 2-plasmin inhibitor gene (PLI) was mapped by in situ hybridization using a genomic DNA probe which contained exons coding for the signal peptide and a portion of the mature protein.
(17) Kinetics during the phase of maximal and constant plasmin formation were not influenced by plasmin pretreatment of FCB-2.
(18) VN associated with the ECM may confer retention and bioactivity to PAI-1, potentially facilitating both pericellular regulation of plasmin generation and the rapid hepatic clearance of plasminogen activators.
(19) Urokinase first cleaves an internal peptide bond in plasminogen, leading to two-chain disulfide-linked plasmin molecule.
(20) During the operation and the postoperative period various hemorheological and hemostasiological alterations acquire clinical significance: 1. hyperreagibility of platelets with increased aggregation and adhesion tendency 2. changes in fibrinogen, albumin, and globulin concentrations, which affect viscosity and red cell aggregation 3. impairment of red cell deformability 4. increase in clotting factors 5. disturbance of fibrinolysis characterized by diminution of plasmatic plasmin and increase in antiplasmin activity In addition, anesthetic techniques have also been shown to affect hemorheological and hemostasiological parameters.
Plastin
Definition:
(n.) A substance associated with nuclein in cell nuclei, and by some considered as the fundamental substance of the nucleus.
Example Sentences:
(1) Two methods to preserve gastrointestinal tract (GIT) organs and tissues, plastic coating (PC) and plastination (PN), were investigated and compared.
(2) Twelve cadaver achilles tendons were investigated by means of the plastination method.
(3) These candidate genes can be divided into 5 groups: signal transduction proteins (RB1, inhibin alpha, FLT1, and HOX4B), muscle-specific products [myosin light chain, desmin, and nicotinic cholinergic receptor subunits gamma and delta (CHRNG and CHRND)], extracellular matrix proteins (collagen type VI alpha 3 chain, elastin, and fibronectin), transformation-associated products (intestinal alkaline phosphatase and L-plastin), and other genes (esterase D).
(4) Both schedules used plasma activated partial thrombo-plastin time (P-APTT) for adjustment of heparin infusion and aimed at the same therapeutic interval for P-APTT (1.5-2 times the value in normal pooled plasma).
(5) With the present trend in decreased requests for autopsies to be performed, the method of plastination and videotaping coupled with more traditional teaching methods provides a way to expand the information and knowledge that may be obtained from each autopsy in an academic medical center.
(6) In this model natural recombinant hirudins, rHV2 and rHV2-Lys47 injected 5 min before thrombo-plastin totally inhibited thrombosis in the same micrograms range as heparin or natural hirudin extracted from leeches.
(7) Fimbrin is also homologous in sequence with human L-plastin and T-plastin.
(8) A technique of plastination and its application to the preservation of oral pathology teaching specimens is presented.
(9) A microangiography of all femora occurred and after plastination transparent slices were produced.
(10) By means of macroscopic preparations and plastinated crossections of human bodies in the regions of the mons pubis a flat flat-pad (corpus adiposum), covered by connective tissue, was found, which can be demarcated from the subcutaneous adipose tissue.
(11) The finished plastinated specimen is dry to the touch, odorless, and nontoxic, yet it maintains its original shape and, in many cases, is reasonably close in color and consistency.
(12) Fibroblasts transformed in vitro by chemical carcinogens or SV40 virus and tumor-derived cancer cells of fibroblastoid or epithelioid origin usually express plastin and p220, a minor phosphorylated form of plastin.
(13) A morphological study concerning the development and arrangement of the connective tissue in the retrorectal region was performed by investigating 300-700 micron thick sections through fetal pelves, plastinated with the epoxy resin E 12 and cut with a diamond wire-saw.
(14) The modified Spalteholz technique with decalcification of sections and second plastination procedure for the preparation of transparent decalcified bone sections is described.
(15) The endotoxin-stimulated monocytes with their elevated tissue thrombo-plastin activity thus may play an important part in development of the DIC which so often follows septicemia.
(16) We report here that plastin is expressed as one of the most abundant proteins of normal, untransformed lymphocytes.
(17) A new histological method basing on the plastination technique (v. Hagens, Tiedemann, Kriz 1987) has recently been developed and applied to research in human fetal development.
(18) The relative values of different microangiographic techniques have been determined for the first time by means of further developments of the Spalteholz and plastination techniques, because they have provided the possibility of standardizing sections.
(19) Altmejd makes Damien Hirst look like a restrained aesthete, and Gunther von Hagen's plastinated corpses look like a major contribution to science.
(20) Plastinated whole jaws are still readily identifiable from antemortem records.