(n.) The gratification of the senses or of the mind; agreeable sensations or emotions; the excitement, relish, or happiness produced by the expectation or the enjoyment of something good, delightful, or satisfying; -- opposed to pain, sorrow, etc.
(n.) Amusement; sport; diversion; self-indulgence; frivolous or dissipating enjoyment; hence, sensual gratification; -- opposed to labor, service, duty, self-denial, etc.
(n.) What the will dictates or prefers as gratifying or satisfying; hence, will; choice; wish; purpose.
(n.) That which pleases; a favor; a gratification.
(v. t.) To give or afford pleasure to; to please; to gratify.
(v. i.) To take pleasure; to seek pursue pleasure; as, to go pleasuring.
Example Sentences:
(1) The bank tellers who saw their positions filled by male superiors took special pleasure in going to the bank and keeping them busy.
(2) Black males with low intentions to use condoms reported significantly more negative attitudes about the use of condoms (eg, using condoms is disgusting) and reacted with more intense anger when their partners asked about previous sexual contacts, when a partner refused sex without a condom, or when they perceived condoms as interfering with foreplay and sexual pleasure.
(3) Walking for pleasure was generally the most common physical activity for both sexes throughout the year.
(4) I like to think of Shakespeare as one delicious smorgasbord that I have a lifelong pleasure in eating.
(5) Saudi Arabia As one might imagine, Saudi television rather wants for the bounty we enjoy here - reality shows in which footballers' mistresses administer handjobs to barnyard animals, and all those other things which make living in the godless west such a pleasure.
(6) The clashes between the moralistic Levin and his friend Oblonsky, sometimes affectionate, sometimes angry, and Levin's linkage of modernity to Oblonsky's attitudes – that social mores are to be worked around and subordinated to pleasure, that families are base camps for off-base nooky – undermine one possible reading of Anna Karenina , in which Anna is a martyr in the struggle for the modern sexual freedoms that we take for granted, taken down by the hypocritical conservative elite to which she, her lover and her husband belong.
(7) Data from human and animal studies indicate a correlation between ictal pleasure or reinforcement and the subject's ability to induce seizures.
(8) I have had the awe-inducing pleasure of standing alone among the giant trees, both sequoias and redwoods, and hearing nothing but the chatter of the squirrels and the high wind in the tallest branches.
(9) Nondrinkers reported a greater likelihood of both positive and negative effects; heavier drinkers reported more pleasurable effects.
(10) A survey last year found that almost 4 million British adults never read books for pleasure , and as in Pellerin’s case, a lack of time was the dominant factor.
(11) We like to enjoy ourselves, if you enjoy the way you play you’ll win a lot of games.” It is a long time, and several managers, since Sunderland fans have derived any sustained pleasure from observing their team in action and sure enough, watching Allardyce’s charges was once again, a somewhat gruelling experience.
(12) (Like humans, they have sex for pleasure as well as for procreation.)
(13) But a big part of the High Line's success is its planting and landscaping, which is intelligent, imaginative and well considered, in the way it converts industrial relics into a place of urban pleasure.
(14) There is an enjoyment that comes with owning it, a pleasure, but also he is an astute businessman.
(15) He confessed to over-indulgence in this pleasure at some stages of his life, and to the recreational use of drugs.
(16) The opposite of a guilty pleasure: a guilty torture.
(17) We would have been denied the pleasure of seeing the official Tongan team anorak, for a start, and it was a bit special, wasn’t it?
(18) "It gives them a sense of pleasure when they believe that they've destroyed me or taken me down.
(19) No changes in plasma beta-endorphin or ACTH concentrations were observed with pentagastrin nor after the meal, despite the combination of very high sensory pleasure with intake of a very large amount of food.
(20) It was the book that turned me on to the intoxicating pleasure of theatre criticism and – well-thumbed and much borrowed from – it has stayed with me ever since.
Stimulation
Definition:
(n.) The act of stimulating, or the state of being stimulated.
(n.) The irritating action of various agents (stimuli) on muscles, nerves, or a sensory end organ, by which activity is evoked; especially, the nervous impulse produced by various agents on nerves, or a sensory end organ, by which the part connected with the nerve is thrown into a state of activity; irritation.
Example Sentences:
(1) Stimulation of human leukocytes with various chemical mediators such as TPA, f-Met-Leu-Phe, LTB4, etc.
(2) The optimal size for stimulation was between 5 degrees and 12 degrees (visual angle).
(3) After stimulation with lipopolysaccharide and calcium ionophore A23187, culture supernatants of clones c18A and c29A showed cytotoxic activity against human melanoma A375 Met-Mix and other cell lines which were resistant to the tumor necrosis factor, lymphotoxin and interleukin 1.
(4) Apparently, the irradiation with visible light of a low intensity creates an additional proton gradient and thus stimulates a new replication and division cycle in the population of cells whose membranes do not have delta pH necessary for the initiation of these processes.
(5) In conclusion, in S-rats a glucose-stimulated insulin release is accompanied by an increase in IBF, but this is not observed in P-rats.
(6) Stimulation is also observed with mixtures of APC expressing DPw3 and APC expressing A1, and likewise, DPw3+ APC become stimulatory when preincubated with supernatants from A1-positive cells.
(7) We have previously shown that serotonin is present in secretory granules of frog adrenochromaffin cells; concurrently, we have demonstrated that serotonin is a potent stimulator of corticosterone and aldosterone secretion by adrenocortical cells.
(8) Cyclic AMP stimulated phosphorylation by [gamma-32P]ATP of two proteins of apparent Mr = 20,000 and 7,000 that were concentrated in sarcoplasmic reticulum, but the stimulation was markedly dependent on the presence of added soluble cyclic AMP-dependent protein kinase.
(9) We have investigated a physiological role of endogenous insulin on exocrine pancreatic secretion stimulated by a liquid meal as well as exogenous secretin and cholecystokinin octapeptide (CCK-8) in conscious rats.
(10) Whether hen's egg yolk can be used as a sperm motility stimulant in the treatment of such conditions as asthenospermia and oligospermia is subjected for further study.
(11) Some of those drugs are able to stimulate the macrophages, even in an aspecific way, via the gut associated lymphatic tissue (GALT), that is in connection with the bronchial associated lymphatic tissue (BALT).
(12) The results also suggest that the dispersed condition of pigment in the melanophores represents the "resting state" of the melanophores when they are under no stimulation.
(13) dl-Methionine stimulated the synthesis of cephalosporins when added after the growth phase.
(14) Bradykinin also stimulated arachidonic acid release in decidual fibroblasts, an effect which was potentiated in the presence of epidermal growth factor (EGF), but which was not accompanied by an increase in PGF2 alpha production.
(15) Pokeweed mitogen-stimulated rat spleen cells were identified as a reliable source of rat burst-promoting activity (PBA), which permitted development of a reproducible assay for rat bone marrow erythroid burst-forming units (BFU-E).
(16) To investigate the mechanism of enhanced responsiveness of cholesterol-enriched human platelets, we compared stimulation by surface-membrane-receptor (thrombin) and post-receptor (AlF4-) G-protein-directed pathways.
(17) Estimates of potential for gastrointestinal side effects using the rat enteropooling assay and in vivo monkey effects indicate that diarrhea will be substantially reduced with retention of uterine stimulating potency.
(18) Because it has been suggested that the lathyrogen, BAPN, may stimulate the release of proteases, the protease inhibitors Trasylol and epsilon-aminocaproic acid (EACA) were given alone or in combination to BAPN-treated rats.
(19) The present study was designed to test the hypothesis that the decreased Epi response following ET was due to 1) depletion of adrenal Epi content such that adrenomedullary stimulation would not release Epi, 2) decreased Epi release with direct stimulation, i.e., desensitization of release, or 3) decreased afferent signals generated by ET itself.
(20) Stimulation of atrial H1-receptors is suggested to directly cause an increase in Ca-channel conductance independent of intracellular cAMP content.