(n.) That which pricks or pierces; the sharp end of anything, esp. the sharp end of a piercing instrument, as a needle or a pin.
(n.) An instrument which pricks or pierces, as a sort of needle used by engravers, etchers, lace workers, and others; also, a pointed cutting tool, as a stone cutter's point; -- called also pointer.
(n.) Anything which tapers to a sharp, well-defined termination. Specifically: A small promontory or cape; a tract of land extending into the water beyond the common shore line.
(n.) The mark made by the end of a sharp, piercing instrument, as a needle; a prick.
(n.) An indefinitely small space; a mere spot indicated or supposed. Specifically: (Geom.) That which has neither parts nor magnitude; that which has position, but has neither length, breadth, nor thickness, -- sometimes conceived of as the limit of a line; that by the motion of which a line is conceived to be produced.
(n.) An indivisible portion of time; a moment; an instant; hence, the verge.
(n.) A mark of punctuation; a character used to mark the divisions of a composition, or the pauses to be observed in reading, or to point off groups of figures, etc.; a stop, as a comma, a semicolon, and esp. a period; hence, figuratively, an end, or conclusion.
(n.) Whatever serves to mark progress, rank, or relative position, or to indicate a transition from one state or position to another, degree; step; stage; hence, position or condition attained; as, a point of elevation, or of depression; the stock fell off five points; he won by tenpoints.
(n.) That which arrests attention, or indicates qualities or character; a salient feature; a characteristic; a peculiarity; hence, a particular; an item; a detail; as, the good or bad points of a man, a horse, a book, a story, etc.
(n.) Hence, the most prominent or important feature, as of an argument, discourse, etc.; the essential matter; esp., the proposition to be established; as, the point of an anecdote.
(n.) A small matter; a trifle; a least consideration; a punctilio.
(n.) A dot or mark used to designate certain tones or time
(n.) A dot or mark distinguishing or characterizing certain tones or styles; as, points of perfection, of augmentation, etc.; hence, a note; a tune.
(n.) A dot placed at the right hand of a note, to raise its value, or prolong its time, by one half, as to make a whole note equal to three half notes, a half note equal to three quarter notes.
(n.) A fixed conventional place for reference, or zero of reckoning, in the heavens, usually the intersection of two or more great circles of the sphere, and named specifically in each case according to the position intended; as, the equinoctial points; the solstitial points; the nodal points; vertical points, etc. See Equinoctial Nodal.
(n.) One of the several different parts of the escutcheon. See Escutcheon.
(n.) One of the points of the compass (see Points of the compass, below); also, the difference between two points of the compass; as, to fall off a point.
(n.) A short piece of cordage used in reefing sails. See Reef point, under Reef.
(n.) A a string or lace used to tie together certain parts of the dress.
(n.) Lace wrought the needle; as, point de Venise; Brussels point. See Point lace, below.
(n.) A switch.
(n.) An item of private information; a hint; a tip; a pointer.
(n.) A fielder who is stationed on the off side, about twelve or fifteen yards from, and a little in advance of, the batsman.
(n.) The attitude assumed by a pointer dog when he finds game; as, the dog came to a point. See Pointer.
(n.) A standard unit of measure for the size of type bodies, being one twelfth of the thickness of pica type. See Point system of type, under Type.
(n.) A tyne or snag of an antler.
(n.) One of the spaces on a backgammon board.
(n.) A movement executed with the saber or foil; as, tierce point.
(n.) To give a point to; to sharpen; to cut, forge, grind, or file to an acute end; as, to point a dart, or a pencil. Used also figuratively; as, to point a moral.
(n.) To direct toward an abject; to aim; as, to point a gun at a wolf, or a cannon at a fort.
(n.) Hence, to direct the attention or notice of.
(n.) To supply with punctuation marks; to punctuate; as, to point a composition.
(n.) To mark (as Hebrew) with vowel points.
(n.) To give particular prominence to; to designate in a special manner; to indicate, as if by pointing; as, the error was pointed out.
(n.) To indicate or discover by a fixed look, as game.
(n.) To fill up and finish the joints of (a wall), by introducing additional cement or mortar, and bringing it to a smooth surface.
(n.) To cut, as a surface, with a pointed tool.
(v. i.) To direct the point of something, as of a finger, for the purpose of designating an object, and attracting attention to it; -- with at.
(v. i.) To indicate the presence of game by fixed and steady look, as certain hunting dogs do.
(v. i.) To approximate to the surface; to head; -- said of an abscess.
Example Sentences:
(1) Single-case experimental designs are presented and discussed from several points of view: Historical antecedents, assessment of the dependent variable, internal and external validity and pre-experimental vs experimental single-case designs.
(2) Well tolerated from the clinical and laboratory points of view, it proved remarkably effective.
(3) We are pursuing legal action because there are still so many unanswered questions about the viability of Shenhua’s proposed koala plan and it seems at this point the plan does not guarantee the survival of the estimated 262 koalas currently living where Shenhua wants to put its mine,” said Ranclaud.
(4) She knows you can’t force the opposition to submit to your point of view.
(5) The isoelectric points (pI) of E1 and E2 for all VEE strains studied were approx.
(6) Ofcom will conduct research, such as mystery shopping, to assess the transparency of contractual information given to customers by providers at the point of sale".
(7) Fifty-two pairs of canine femora were tested to failure in four-point bending.
(8) A one point dilution enzyme-linked immunosorbent assay (ELISA) procedure suitable for determining immunoglobulin G (IgG) antibody levels to Toxoplasma gondii (T. gondii) in community seroepidemiological surveys is described.
(9) Subsequent isoelectric focusing in sucrose revealed an isoelectric point of 9.0-9.2.
(10) Gross deformity, point tenderness and decrease in supination and pronation movements of the forearm were the best predictors of bony injury.
(11) Whole-virus vaccines prepared by Merck Sharp and Dohme (West Point, Pa.) and Merrell-National Laboratories (Cincinnati, Ohio) and subunit vaccines prepared by Parke, Davis and Company (Detroit, Mich.) and Wyeth Laboratories (Philadelphia, Pa.) were given intramuscularly in concentrations of 800, 400, or 200 chick cell-agglutinating units per dose.
(12) A Monte Carlo simulation was performed to characterize the spatial and energy distribution of bremsstrahlung radiation from beta point sources important to radioimmunotherapy (RIT).
(13) From the social economic point of view nosocomial infections represent a very important cost factor, which could be reduced to great deal by activities for prevention of nosocomial infection.
(14) He said Germany was Russia’s most important economic partner, and pointed out that 35% of German gas originated in Russia.
(15) Many examples are given to demonstrate the applications of these programs, and special emphasis has been laid on the problem of treating a point in tissue with different doses per fraction on alternate treatment days.
(16) In 11 of the 22 cells PAI-1 mRNA and in 6 of the 22 cells PAI-2 mRNA was found, pointing to a possible role of plasminogen activator inhibitors in the tumor-related plasminogen activator activity.
(17) Sequence specific binding of protein extracts from 13 different yeast species to three oligonucleotide probes and two points mutants derived from Saccharomyces cerevisiae DNA binding proteins were tested using mobility shift assays.
(18) Recent studies point to the involvement of regulatory peptides in diseases of the gut and lung.
(19) The positive predictive accuracy of a biophysical profile score of 0, with mortality and morbidity used as end points, was 100%.
(20) The starting point is the idea that the current system, because it works against biodiversity but fails to increase productivity, is broken.
Sharp
Definition:
(superl.) Having a very thin edge or fine point; of a nature to cut or pierce easily; not blunt or dull; keen.
(superl.) Terminating in a point or edge; not obtuse or rounded; somewhat pointed or edged; peaked or ridged; as, a sharp hill; sharp features.
(superl.) Affecting the sense as if pointed or cutting, keen, penetrating, acute: to the taste or smell, pungent, acid, sour, as ammonia has a sharp taste and odor; to the hearing, piercing, shrill, as a sharp sound or voice; to the eye, instantaneously brilliant, dazzling, as a sharp flash.
(superl.) High in pitch; acute; as, a sharp note or tone.
(superl.) Raised a semitone in pitch; as, C sharp (C/), which is a half step, or semitone, higher than C.
(superl.) So high as to be out of tune, or above true pitch; as, the tone is sharp; that instrument is sharp. Opposed in all these senses to flat.
(superl.) Very trying to the feelings; piercing; keen; severe; painful; distressing; as, sharp pain, weather; a sharp and frosty air.
(superl.) Cutting in language or import; biting; sarcastic; cruel; harsh; rigorous; severe; as, a sharp rebuke.
(superl.) Of keen perception; quick to discern or distinguish; having nice discrimination; acute; penetrating; sagacious; clever; as, a sharp eye; sharp sight, hearing, or judgment.
(superl.) Eager in pursuit; keen in quest; impatient for gratification; keen; as, a sharp appetite.
(superl.) Keenly or unduly attentive to one's own interest; close and exact in dealing; shrewd; as, a sharp dealer; a sharp customer.
(superl.) Composed of hard, angular grains; gritty; as, sharp sand.
(superl.) Steep; precipitous; abrupt; as, a sharp ascent or descent; a sharp turn or curve.
(superl.) Uttered in a whisper, or with the breath alone, without voice, as certain consonants, such as p, k, t, f; surd; nonvocal; aspirated.
(adv.) To a point or edge; piercingly; eagerly; sharply.
(adv.) Precisely; exactly; as, we shall start at ten o'clock sharp.
(n.) A sharp tool or weapon.
(n.) The character [/] used to indicate that the note before which it is placed is to be raised a half step, or semitone, in pitch.
(n.) A sharp tone or note.
(n.) A portion of a stream where the water runs very rapidly.
(n.) A sewing needle having a very slender point; a needle of the most pointed of the three grades, blunts, betweens, and sharps.
(n.) Same as Middlings, 1.
(n.) An expert.
(v. t.) To sharpen.
(v. t.) To raise above the proper pitch; to elevate the tone of; especially, to raise a half step, or semitone, above the natural tone.
(v. i.) To play tricks in bargaining; to act the sharper.
(v. i.) To sing above the proper pitch.
Example Sentences:
(1) Basal 20 alpha DHP levels remained low until a sharp rise at mid pro-oestrus.
(2) Whole-virus vaccines prepared by Merck Sharp and Dohme (West Point, Pa.) and Merrell-National Laboratories (Cincinnati, Ohio) and subunit vaccines prepared by Parke, Davis and Company (Detroit, Mich.) and Wyeth Laboratories (Philadelphia, Pa.) were given intramuscularly in concentrations of 800, 400, or 200 chick cell-agglutinating units per dose.
(3) Gonadectomy of females was accompanied by changes in the activity of individual HAS links in different direction--some reduction of ACTH in the hypophysis, a sharp and significant fall of the peripheral blood glucocorticoid level and a marked significant elevation of hydrococortisone production in the adrenal cortex in vitro.
(4) The University of the Arts London and Sunderland, Sheffield Hallam, Manchester Met and Leeds Met university have also experienced sharp declines in applications.
(5) A sharp decrease in oxygen uptake occurred in Neurospora crassa cells that were transferred from 30 degrees C to 45 degrees C, and the respiration that resumed later at 45 degrees C was cyanide-insensitive.
(6) In contrast to findings in the rat and dog, no sharp drop but a gradual fall in CLi was observed at decreasing FENa values down to 0.02%.
(7) A more specific differentiation, as indicated by the sharp increase in GAD levels which was concurrent with an increase in interneuronal contacts, lagged behind the initial growth.
(8) It appears that the decline in plasma IGF-I lags considerably behind the sharp fall in plasma GH levels and expression of hepatic IGF-I mRNA.
(9) Supplementation of Mg resulted in a sharp increase in serum PTH level with a rapid disappearance of the dissociation between the two immunoassays of PTH.
(10) A.CA animals were extremely susceptible, showing a sharp and sustained increase in parasitemia starting on day 12, followed by death no later than day 15 post-inoculation.
(11) There was a sharp transition with actin nearly saturated with S1: when the S1 to actin ratio was low, the kinetics were fast (K1 greater than 300 microM, k2 greater than 40 s-1); when it was high, they were slow (K1 = 14 microM, k2 = 2 s-1).
(12) Low calcium causes an increase in optimum frequency, a decrease in current threshold, and an increase in sharpness of tuning in both real axons and axons computed according to the Hodgkin-Huxley formulation; high calcium causes opposite effects.
(13) The Tea Party movement has turned climate denial into a litmus test of conservative credentials – and that has made climate change one of the most sharp divisions between Obama and Romney.
(14) The presence in lamprey kidney of a loop which is similar to Henle's loop in mammals and birds indicates that the development of the system of osmotic concentration conditioned by the formation in the kidney of the medulla and from a sharp increase in renal arterial blood supply.
(15) There is no longer a sharp dividing line between working and rentiering.
(16) We are going to see a sharp fall unless sellers hold the sector up by making aggressive offers.
(17) A sharp increase in the intensity of lipids biochemiluminiscence and decrease in the tissue homogenates biochemiluminiscence were observed during the period of progressive tumour growth on the 6-8 days following introduction of the virus.
(18) By no means is this a new theme, but it has taken on an added sharpness and urgency after the conferences.
(19) The blood lymphocytes were small with scanty cytoplasm, densely condensed nuclear chromatin, and deep clefts originating in sharp angles from the nuclear surface.
(20) In sharp contrast, the coverage provided by the various mainstream news channels and newspapers not only seems – with some exceptions – unresponsive and stilted, but often non-existent.