(1) On the basis of genetic, phenotypic and physiological criteria, these mutants are divided into four groups: 1) the cytochrome aa3 and b deficient "poky" variants that are defective in mitochondrial ribosomes assembly, 2) the cytochrome aa3 deficient mutants, [mi-3] and [exn-5], that appear to have genetic lesions affecting a component of a regulatory system controlling cytochrome aa3 synthesis, 3) the cytochrome aa3 and b deficient "stopper" mutants with physiological lesions that probably affect mitochondrial protein synthesis, and 4) cni-3, a mutant that is constitutive for an inducible mitochondrial cyanide-insensitive oxidase in spite of having a normal cytochrome mediated electron-transport system.
(2) Cell respiration in wild type and poky was studied as part of a long-term investigation of cyanide-resistant respiration in Neurospora.
(3) Six independently isolated Group 1 extranuclear mutants, namely [exn-1], [exn-2], [exn-4-a1, [stp-b1], [SG-1] and [SG-3-A1, which have growth and cytochrome phenotypes similar to [poky] also were found to be deficient in small subunits of mitochondrial ribosomes.
(4) Seven nonallelic nuclear suppressors of [poky] result in increased concentrations of the mt small rRNA and pre-rRNAs, but do not restore the ability to synthesize small rRNAs having the correct 5' ends.
(5) Group I consists of 8 female-fertile variants with both poky-like growth and cytochrome defects.
(6) Two-dimensional gel electrophoresis was used to examine mit ribosomal proteins from [poky] and six additional extra-nuclear mutants with defects in the assembly of mit small subunits.
(7) Six nuclear suppressors of the (poky) cytoplasmic mutant (sup-1, sup-3, sup-4, sup-5, sup-10, sup-14) have been obtained in Neurospora crassa.
(8) However, the transmission of the [poky] mutation does not appear to be correlated with the transmission of either of these insertions or of other physical markers.
(9) Mitochondria from the cytochrome-deficient mutant poky carried out substrate-driven K+ uptake at reduced rates, but oligomycin-sensitive, ATP-driven K+ uptake at rates about 60% greater than those shown by wild-type mitochondria.
(10) But actually Chote's team is only about 20-strong and they operate from a rather poky office on Victoria Street.
(11) We have compared the adenosine triphosphatase (ATPase) activity of mitochondria prepared from wild-type Neurospora crassa and from poky, a maternally inherited mutant known to possess defective mitochondrial ribosomes and reduced amounts of cytochromes aa3 and b. poky contains two distinct forms of mitochondrial ATPase.
(12) Pokie Nation, set to air next week on the ABC, has been edited to amend the claim.
(13) In all these experiments, no difference was detected between wild type and poky in base sequence or methylation of either 19 S or 25 S RNA.
(14) The six suppressors are nonallelic, suppress the phenotypic effects of (stp-Bl) in addition to (poky), but have no effect on the phenotype expression of the (mi-3) cytoplasmic mutant.
(15) An analysis of the paramagnetic components present in mitochondria isolated from the poky mutant of Neurospora crassa is described.
(16) Orta filmed the death of Eric Garner , capturing the moment the 43-year-old was placed in a banned chokehold by an NYPD officer and uttered his last words: “I can’t breathe.” Lawyers Ken Perry and William Aronin sit in the poky downtown Manhattan apartment that serves as their office.
(17) The mitochondrial phenotype of [poky] and other extranuclear Neurospora mutants is known to predominate over that of wild type in heteroplasmons.
(18) They are not allowed to draw in court, so they must observe, make notes about someone’s characteristics and clothes, and then retreat to a poky press room where they sketch and colour at high speed.
(19) The residual small rRNAs in [poky] appear to be synthesized via the upstream promoter(s), but are missing 37-44 nucleotides from their 5' ends, indicating either that pre-rRNAs are processed abnormally or that abnormal 5' RNA ends are unstable.
(20) The ribosomal defect shows an extrachromosomal pattern of inheritance in crosses of poky with wild type.
Porky
Definition:
Example Sentences:
(1) He was the kind of bloke you’d book the morning cutting session with and have a pint with him at lunchtime – you wouldn’t book the afternoon one because that’d be after his pint!” Porky also encouraged bands to scratch in their own messages.
(2) With its brightly punchy tomato sauce, good mound of rocket, decent if sparingly distributed mozzarella and porky, spicy salsiccia sausage, my sampler largely backed up such hype.
(3) Some did (the Porky's franchise ran and ran) and some didn't (anyone remember Squeeze Play?)
(4) Well how come you've been telling me a big bleedin' porky for the last six months?
(5) Power companies that do not meet their legal renewables obligations are telling porkies if they suggest that when you sign up for their green tariff, they will deliver more green electricity.
(6) April 30, 2015 O’Shaughnessy said: “Despite the odd porky Clegg is doing quite well.” And then added, “For clarity: I respect Clegg voting for £9,000 fees cos it’s a good policy.
(7) Now imagine that your neighbour has quietly accumulated debts of £30,000 over the years, and told a few porkies along the way to get their credit card limit raised.
(8) The kind of bawdy, sexually explicit antics that began with Porky's and resurfaced in the teenage and twentysomething-targeted "grossout" movies of the late 90s were extending their hold in films for those a little older.
(9) The roasted aroma of these porky treats emanates from La Reina de la Roma, a simple fonda with a few tables spilling on to the street, in the old Colonia Roma neighborhood, near its interesting central market.
(10) We have sex whenever we can and when we can’t we masturbate, ’cos being in a band takes up a lot of our time [Hillel starts to play an imaginary violin].” You once said: “We want to make the world a better place with our music.” I presume that’s a major-league porky pie?
(11) The patients were subdivided into two groups: a complex of commonly used curative measures according to the intensive therapy for AHI was applied in Group A (67 patients); in Group B (59 patients), alongside with the above measures, temporary organ substitution by hemoperfusion through a suspension of active porky hepatocytes was also performed.
(12) It also added dozens of diversions, the most needless of which was the ability of your controlled character, a young man named CJ, to get fat from eating health-restoring pizza and burgers – fat that could be burned off only by hauling CJ's porky ass down to the gym to ride a stationary bike and lift weights.
(13) Later imitations such as the Porky's series took the bawdiness of Animal House to a new level of explicitness, but overlooked the genuinely innovative aspect of the movie: its sophisticated frankness about rebellion.
(14) 1970s: a humble record-cutter popularises the “run-off groove” message George “Porky” Peckham cut records for the Beatles, Genesis and Led Zeppelin before setting up his own business in London’s West End, attracting punk and indie bands with cash-price deals.
(15) There’s not only the discount the government has inflicted on itself by telling porkies and playing cynical games with the voters, Abbott also faces the difficulties of the current political communication environment.
(16) When he finished a job, he’d “sign” his nickname into the deadwax between the music and the label – either Pecko, Pecko Duck, Porky, or his most famous inscription, “A Porky Prime Cut” – and add dryly humorous phrases.
(17) Marrying the ultimate in comfort and cured meat, J&D’s Bacon Scented Underwear represents the gold standard of meat-scented luxury undergarments,” says the Seattle-based food company behind the porky pants.
(18) As anyone who has ever tried to keep a car on the potholed roads of Bihar, in northern India, will know, that description is a giant porky.
(19) Why are former footballers like Alan Hansen and the one who looks like a porky hairdresser paid more than Jeremy Paxman , the most authoritative broadcast journalist in Britain?
(20) Please, send me your autograph.” Labour MP Jonathan Ashworth said: “This is all rather embarrassing for Eric Pickles, who’s been caught telling porkie pies about his pulling prowess.