(1) On the basis of genetic, phenotypic and physiological criteria, these mutants are divided into four groups: 1) the cytochrome aa3 and b deficient "poky" variants that are defective in mitochondrial ribosomes assembly, 2) the cytochrome aa3 deficient mutants, [mi-3] and [exn-5], that appear to have genetic lesions affecting a component of a regulatory system controlling cytochrome aa3 synthesis, 3) the cytochrome aa3 and b deficient "stopper" mutants with physiological lesions that probably affect mitochondrial protein synthesis, and 4) cni-3, a mutant that is constitutive for an inducible mitochondrial cyanide-insensitive oxidase in spite of having a normal cytochrome mediated electron-transport system.
(2) Cell respiration in wild type and poky was studied as part of a long-term investigation of cyanide-resistant respiration in Neurospora.
(3) Six independently isolated Group 1 extranuclear mutants, namely [exn-1], [exn-2], [exn-4-a1, [stp-b1], [SG-1] and [SG-3-A1, which have growth and cytochrome phenotypes similar to [poky] also were found to be deficient in small subunits of mitochondrial ribosomes.
(4) Seven nonallelic nuclear suppressors of [poky] result in increased concentrations of the mt small rRNA and pre-rRNAs, but do not restore the ability to synthesize small rRNAs having the correct 5' ends.
(5) Group I consists of 8 female-fertile variants with both poky-like growth and cytochrome defects.
(6) Two-dimensional gel electrophoresis was used to examine mit ribosomal proteins from [poky] and six additional extra-nuclear mutants with defects in the assembly of mit small subunits.
(7) Six nuclear suppressors of the (poky) cytoplasmic mutant (sup-1, sup-3, sup-4, sup-5, sup-10, sup-14) have been obtained in Neurospora crassa.
(8) However, the transmission of the [poky] mutation does not appear to be correlated with the transmission of either of these insertions or of other physical markers.
(9) Mitochondria from the cytochrome-deficient mutant poky carried out substrate-driven K+ uptake at reduced rates, but oligomycin-sensitive, ATP-driven K+ uptake at rates about 60% greater than those shown by wild-type mitochondria.
(10) But actually Chote's team is only about 20-strong and they operate from a rather poky office on Victoria Street.
(11) We have compared the adenosine triphosphatase (ATPase) activity of mitochondria prepared from wild-type Neurospora crassa and from poky, a maternally inherited mutant known to possess defective mitochondrial ribosomes and reduced amounts of cytochromes aa3 and b. poky contains two distinct forms of mitochondrial ATPase.
(12) Pokie Nation, set to air next week on the ABC, has been edited to amend the claim.
(13) In all these experiments, no difference was detected between wild type and poky in base sequence or methylation of either 19 S or 25 S RNA.
(14) The six suppressors are nonallelic, suppress the phenotypic effects of (stp-Bl) in addition to (poky), but have no effect on the phenotype expression of the (mi-3) cytoplasmic mutant.
(15) An analysis of the paramagnetic components present in mitochondria isolated from the poky mutant of Neurospora crassa is described.
(16) Orta filmed the death of Eric Garner , capturing the moment the 43-year-old was placed in a banned chokehold by an NYPD officer and uttered his last words: “I can’t breathe.” Lawyers Ken Perry and William Aronin sit in the poky downtown Manhattan apartment that serves as their office.
(17) The mitochondrial phenotype of [poky] and other extranuclear Neurospora mutants is known to predominate over that of wild type in heteroplasmons.
(18) They are not allowed to draw in court, so they must observe, make notes about someone’s characteristics and clothes, and then retreat to a poky press room where they sketch and colour at high speed.
(19) The residual small rRNAs in [poky] appear to be synthesized via the upstream promoter(s), but are missing 37-44 nucleotides from their 5' ends, indicating either that pre-rRNAs are processed abnormally or that abnormal 5' RNA ends are unstable.
(20) The ribosomal defect shows an extrachromosomal pattern of inheritance in crosses of poky with wild type.
Swell
Definition:
(v. i.) To grow larger; to dilate or extend the exterior surface or dimensions, by matter added within, or by expansion of the inclosed substance; as, the legs swell in dropsy; a bruised part swells; a bladder swells by inflation.
(v. i.) To increase in size or extent by any addition; to increase in volume or force; as, a river swells, and overflows its banks; sounds swell or diminish.
(v. i.) To rise or be driven into waves or billows; to heave; as, in tempest, the ocean swells into waves.
(v. i.) To be puffed up or bloated; as, to swell with pride.
(v. i.) To be inflated; to belly; as, the sails swell.
(v. i.) To be turgid, bombastic, or extravagant; as, swelling words; a swelling style.
(v. i.) To protuberate; to bulge out; as, a cask swells in the middle.
(v. i.) To be elated; to rise arrogantly.
(v. i.) To grow upon the view; to become larger; to expand.
(v. i.) To become larger in amount; as, many little debts added, swell to a great amount.
(v. i.) To act in a pompous, ostentatious, or arrogant manner; to strut; to look big.
(v. t.) To increase the size, bulk, or dimensions of; to cause to rise, dilate, or increase; as, rains and dissolving snow swell the rivers in spring; immigration swells the population.
(v. t.) To aggravate; to heighten.
(v. t.) To raise to arrogance; to puff up; to inflate; as, to be swelled with pride or haughtiness.
(v. t.) To augment gradually in force or loudness, as the sound of a note.
(n.) The act of swelling.
(n.) Gradual increase.
(n.) Increase or augmentation in bulk; protuberance.
(n.) Increase in height; elevation; rise.
(n.) Increase of force, intensity, or volume of sound.
(n.) Increase of power in style, or of rhetorical force.
(n.) A gradual ascent, or rounded elevation, of land; as, an extensive plain abounding with little swells.
(n.) A wave, or billow; especially, a succession of large waves; the roll of the sea after a storm; as, a heavy swell sets into the harbor.
(n.) A gradual increase and decrease of the volume of sound; the crescendo and diminuendo combined; -- generally indicated by the sign.
(n.) A showy, dashing person; a dandy.
(a.) Having the characteristics of a person of rank and importance; showy; dandified; distinguished; as, a swell person; a swell neighborhood.
Example Sentences:
(1) Furthermore echography revealed a collateral subperiosteal edema and a moderate thickening of extraocular muscles and bone periostitis, a massive swelling of muscles and bone defects in subperiosteal abscesses as well as encapsulated abscesses of the orbit and a concomitant retrobulbar neuritis in orbital cellulitis.
(2) Undaunted by the sickening swell of the ocean and wrapped up against the chilly wind, Straneo, of Woods Hole Oceanographic Institution, one of the world's leading oceanographic research centres, continues to take measurements from the waters as the long Arctic dusk falls.
(3) Axons emerge from proximal dendrites within 50 microns of the soma, and more rarely from the soma, in a tapering initial segment, commonly interrupted by one or two large swellings.
(4) It is a specific clinical picture with extensive soft tissue gas and swelling of the forearm.
(5) Psychiatric morbidity is further increased when adjuvant chemotherapy is used and when treatment results in persistent arm pain and swelling.
(6) Chromatolysis and swelling of the cell bodies of cut axons are more prolonged than after optic nerve section and resolve in more central regions of retina first.
(7) At 7 days axonal swellings were infrequently observed and the main structural feature was a reduction in myelin thickness in affected nerve fibers.
(8) In the companion paper, we quantitatively account for the observation that the ability of a solute to promote fusion depends on its permeability properties and the method of swelling.
(9) Admission venom levels also correlated with the extent of local swelling and the occurrence of tissue necrosis at the site of the bite.
(10) After 40 minutes of coronary occlusion and 20 minutes of reflow, significant cardiac weight gain occurred in association with characteristic alterations in the ischemic region, including widespread interstitial edema and focal vascular congestion and hemorrhage and swelling of cardiac muscle cells.
(11) The intensity of involvement varies in different arteries, localized swelling is of particular importance as a measure of atherosclerotic involvement.
(12) The DTH responses were induced by subcutaneous injection of allogeneic epidermal cells (ECs) and were assayed by footpad swelling.
(13) Adjunctive usage of elastic stockings and intermittent compression pneumatic boots in the perioperative period was helpful in controlling leg swelling and promoting wound healing.
(14) (1970) Endocrinology 87, 993--999), in stimulating both mitochondrial protein synthesis and swelling.
(15) Rapid swelling of the knee following a blow or twisting injury is considered a significant injury.
(16) Attachment appeared to involve a very close physical proximity of treponemes to the cultured cells; at the site of attachment, no changes such as swelling or indentation of the cultured cell surface were observed.
(17) The method is based upon osmotic swelling, sonication and centrifugation in sucrose.
(18) By contrast, all the semen samples that fertilized oocytes showed a 60% or higher reaction in the hypoosmotic swelling test, whereas the majority of the "infertile" semen samples showed less than 60% swelling.
(19) The changes included swelling, blunting, and flattening of epithelial foot processes, were accompanied by decreased stainability of glomerular anionic sites, and were largely reversed by subsequent perfusion with the polyanion heparin.
(20) After 3-5 days of side-arm traction, swelling had usually diminished sufficiently to allow the elbow to be safely hyperflexed to stabilize the fracture after elective closed reduction.