(n.) The doctrine that animals of the same species have sprung from more than one original pair.
Example Sentences:
(1) When power-transformed scores are used to eliminate skewness, there is evidence for one distribution and it is not possible to distinguish single gene from multifactorial (polygenic or cultural) inheritance.
(2) The polygenic control of diabetogenesis in NOD mice, in which a recessive gene linked to the major histocompatibility complex is but one of several controlling loci, suggests that similar polygenic interactions underlie this type of diabetes in humans.
(3) Inheritance of insulin-dependent diabetes mellitus (IDDM) is polygenic, and at least one of the genes conferring susceptibility to diabetes is tightly linked to the MHC.
(4) The M16 line of mice, selected for rapid postweaning gain, exhibits polygenically controlled obesity and hyperphagia.
(5) The maximum lifespan potential is a constitutional feature of speciation and must be subject to polygenic controls acting both in the domain of development and in the domain of the maintenance of macromolecular integrity.
(6) The pattern of familial clusters and the recurrence risk related to the number of affected relatives and to the severity of the disorder in the index patients support the theory of polygenic inheritance, a multifactorial-threshold aetiological model.
(7) The results showed that the low rate of bacterial clearance was recessive, that the rate of clearance was under polygenic control, and that an H-2-linked gene(s) plays a major role.
(8) The results are discussed in terms of 3 models: Lerner's concept of genetical homeostasis, additive and overdominance polygenic models.
(9) The writers agree with Mr Jiang sanduo's opinion that schizophrenic is a polygenic disease with a major dominant gene.
(10) Conditions such as these may be exclusively monogenic, polygenic or environmental, but in most cases both genetic and environmental factors are involved.
(11) The cultural model, the polygenic model, and the pseudopolygenic model share the common feature that all factors which are transmitted from parent to offspring may be represented by one parameter without any loss of information.
(12) The breeding genetic distance measure of a single locus (Carlson & Welch, 1977) is extended to polygenic traits.
(13) Polygenic variation can be maintained by a balance between mutation and stabilizing selection.
(14) Subsequent variance components analysis suggested that unmeasured polygenic loci and unmeasured shared environmental factors together account for at least an additional 36.7% of the variability in normalized fasting plasma glucose, with genes alone accounting for at least 27.3%.
(15) The posited codominant alleles represent the first single-locus component in the polygenic complexes creating susceptibility to seizures and epitomizes the small additive effects classically attributed to such genes.
(16) A new test of goodness of fit for the polygenic threshold model is proposed.
(17) Some of the abnormalities are due to detectable chromosome anomalies, while the majority of fetal abnormalities arise as a result of the interaction of polygenes and environmental factors.
(18) A general linear model of combined polygenic-cultural inheritance is described.
(19) At present, the strongest evidence is for a polygenic effect, not the effect of a single gene or gene locus.
(20) With non significant changes in triglycerides and HDL-C. We conclude that PP can be used as a complement of diet in the management of polygenic hypercholesterolemia.
Polygenist
Definition:
(n.) One who maintains that animals of the same species have sprung from more than one original pair; -- opposed to monogenist.