(a.) One who is potent; one who possesses great power or sway; a prince, sovereign, or monarch.
Example Sentences:
(1) Neuromedin B (C50 6 x 10(-12) M) was 3 times less potent than bombesin-14.
(2) We have previously shown that serotonin is present in secretory granules of frog adrenochromaffin cells; concurrently, we have demonstrated that serotonin is a potent stimulator of corticosterone and aldosterone secretion by adrenocortical cells.
(3) administration of the potent short-acting opioid, fentanyl, elicited inhibition of rhythmic spontaneous reflex increases in vesical pressure (VP) evoked by urinary bladder distension.
(4) A novel bicyclic prostaglandin analogue, (1S)-[1 alpha,2 alpha(Z),3 alpha,4 alpha]-7-[3-[(hexylthio)methyl]-7- oxabicyclo [2.2.1]hept-2-yl]-5-heptenoic acid ((-)-10), and its cogeners were found to be potent antagonists at the TxA2 receptor.
(5) PBOP was as effective as polymyxin B nonapeptide (PMBN), the known very potent permeabilizer.
(6) )-induced gnawing behavior in rats was slightly more potent than that of clocapramine.
(7) We have confirmed this directly by showing that pure CCK is a potent inhibitor of gastric emptying.
(8) The purpose of the present study was to analyze the effects of cromakalim (BRL 34915), a potent drug from a new class of drugs characterized as "K+ channel openers", on the electrical activity of human skeletal muscle.
(9) We conclude that human hepatic lipocytes synthesize TIMP-1, a potent metalloproteinase inhibitor, and that TIMP-1 expression increases with lipocyte activation.
(10) Attachment of the graft to the wound is similar with and without the addition of human basic fibroblast growth factor, a potent angiogenic agent, to the skin replacement before graft placement on wounds.
(11) Substance P, a potent vasodilating peptide, seems to be released from trigeminal nerve endings in response to nervous stimulation and is involved in the transmission of painful stimuli within the periphery.
(12) Addition in the cultures of 4-deoxypyridoxine, a potent antagonist of vitamin B6 coenzymes, concurrently with the mitogen, inhibits the induction of serine hydroxymethyltransferase.
(13) These findings suggest that Sch 40120 is a potent anti-inflammatory agent that may be particularly useful in the treatment of inflammatory diseases such as psoriasis in which leukotrienes appear to be major mediators of the pathological symptoms that characterize the disease state.
(14) Mercury compounds and EDTA were found to be potent inhibitors of proteinase yscJ activity.
(15) We found that whereas idarubicin was 2-5 times more potent than the other three anthracycline analogs against these tumor cell lines, idarubicinol was 16-122 times more active than the other alcohol metabolites against the same three cell lines.
(16) Concanavalin A (con A) is a potent inhibitor of coagulant activity of native tissue factor.
(17) The alpha 2-adrenoceptor agonist clonidine is most potent for stimulating Isc.
(18) Chlorpromazine was clearly the most potent antagonist in all three experimental conditions.
(19) Moreover, the ribosylation inhibitors converted the glucocorticoid antagonist RU-486 into a potent agonist for cytolysis of L1210 cells.
(20) Aortic rings from the rabbit were similarly potently antagonized by the protein kinase C inhibitors, however, K(+)-induced contractions were also equally sensitive to these agents in both rat and rabbit tissues.
Potential
Definition:
(a.) Being potent; endowed with energy adequate to a result; efficacious; influential.
(a.) Existing in possibility, not in actuality.
(n.) Anything that may be possible; a possibility; potentially.
(n.) In the theory of gravitation, or of other forces acting in space, a function of the rectangular coordinates which determine the position of a point, such that its differential coefficients with respect to the coordinates are equal to the components of the force at the point considered; -- also called potential function, or force function. It is called also Newtonian potential when the force is directed to a fixed center and is inversely as the square of the distance from the center.
(n.) The energy of an electrical charge measured by its power to do work; hence, the degree of electrification as referred to some standard, as that of the earth; electro-motive force.
Example Sentences:
(1) Intrathecal injection of zopiclone potentiated morphine antinociception, while the intracerebroventricular injection of zopiclone failed to enhance morphine antinociception and the intracerebroventricular injection of flumazepil to antagonize the intraperitoneal-zopiclone-induced increase in morphine antinociception.
(2) Fibulin is a potential mediator of interactions between adhesion receptors and the cytoskeleton.
(3) The Na+ ionophore, gramicidin, had a small but significant inhibitory effect on Na(+)-dependent KG uptake, demonstrating that KG uptake was not the result of an intravesicular positive Na+ diffusion potential.
(4) Assessment of the likelihood of replication in humans has included in vitro exposure of human cells to the potential pesticidal agent.
(5) The outward currents are sensitive to TEA and their reversal potentials differ.
(6) With NaCl as the major constituent of the bathing solution (potassium-free pipette and external solutions) the reversal potential (Er) of the noradrenaline-evoked current was about 0 mV.
(7) Theophylline kinetics, as an in vivo probe for the potentially toxic cytochrome P-450I pathway of drug metabolism, were studied in 11 healthy volunteers and 11 patients with calcific chronic pancreatitis at Madras, South India.
(8) Interleukin-4 (IL-4) is a cytokine, with potential anti-neoplastic effects.
(9) Another interested party, the University of Miami, had been in talks with the Beckham group over the potential for a shared stadium project.
(10) In the presence of insulin, a qualitatively similar pattern of increasing responses to albumin is observed; the enhancement of each response by insulin is, however, only slightly potentiated by higher albumin concentrations.
(11) The following is a brief review of the history, mechanism of action, and potential adverse effects of neuromuscular blockers.
(12) Hoursoglou thinks a shortage of skilled people with a good grounding in core subjects such as maths and science is a potential problem for all manufacturers.
(13) This modulation results from repetitive, alternating bursts of excitatory and inhibitory postsynaptic potentials, which are caused at least in part by synaptic feedback to the command neurons from identified classes of neurons in the feeding network.
(14) The results show that endolymph is extremely inhomogenous with respect to calcium potentials.
(15) Bradykinin also stimulated arachidonic acid release in decidual fibroblasts, an effect which was potentiated in the presence of epidermal growth factor (EGF), but which was not accompanied by an increase in PGF2 alpha production.
(16) As prolongation of the action potential by TEA facilitates preferentially the hormone release evoked by low (ineffective) frequencies, it is suggested that a frequency-dependent broadening of action potentials which reportedly occurs on neurosecretory neurones may play an important role in the frequency-dependent facilitation of hormone release from the rat neurohypophysis.
(17) This was unlike the action of the calcium channel blocker, cadmium, which reduced the calcium action potential and the a.h.p.
(18) An initial complex-soma inflection was observed on the rising phase of the action potential of some cells.
(19) The HTCA is promising as a potential tool for studying the biology of tumors.
(20) Moreover, in DCVC-treated cells the mitochondria could not be stained with rhodamine-123, indicating severe mitochondrial damage and loss of membrane potential.