(n.) A circular hole formed in the rocky beds of rivers by the grinding action of stones or gravel whirled round by the water in what was at first a natural depression of the rock.
Example Sentences:
(1) The George Bush campaign juggernaut hit the first serious pothole of its cash-fuelled drive to the presidency yesterday, as the Texas governor tried in vain to fend off questions about whether he had used cocaine as a young man.
(2) The Washington DC transportation department put out a tweet saying that the coming apocalypse would have an impact on road maintenance: "Sorry, we will no longer be able to fill your potholes after Saturday."
(3) They once journeyed six hours out of sprawling Mexico City to deliver an order, using specially designed backpacks that protect the food from the city’s potholed streets.
(4) The heat is getting oppressive but we stay alert and try to move with the flow, sticking to the left as much as possible and keeping an eye out for potholes and drain covers whose grilles face the direction of travel – lying in wait to trap unwary bike tyres.
(5) On an otherwise ordinary-looking, potholed street in the district of Victoria Island in Lagos, Nigeria , is a stone encrusted gate with personalised initials.
(6) After eight hours of rallying, Kuti was dismissive of accepting anything short of a full governmental U-turn as he settled down to a spliff in his home, a rambling two-storey affair down a potholed road.
(7) A potholed gravel road runs to a campsite at the mouth of the Mattole river and from there you can wander south down the coast for 25 miles before you come to the next road, at Shelter Cove.
(8) It’s dawn and it’s sub-zero and it’s a potholed car park in Vilnius, eastern Lithuania, and a hobbit is preparing to tell the world about the Holocaust.
(9) The number 38 bus from Bury had skidded out of control on an icy pothole and crushed her against the wall of the Job Centre.
(10) I damaged my car and tyre after hitting a pothole in the dark.
(11) Weah embraces the familiar imagery of African nobility - the lion - and walks with a clear sense of self-worth through the smoking, potholed streets of Monrovia.
(12) Those potholes, cracks and poor surfaces add up to a $4.3tn investment deficit, according to the ASCE.
(13) Temperatures climb above 40C even before the sun has hit the pitted, potholed surface of the streets through which he pushes his vegetable barrow day after day.
(14) Walking through the dismal Leipzig suburbs feels like being transported back 20 years: there are potholes, weeds growing through the tarmac, dozens of uniform grey apartment blocks.
(15) Only 2% of the country's roads are paved, and these are riddled with potholes.
(16) The road falls and rises to the horizon like a highway across the American midwest, except that the surface is brick-red mud and stones and potholes.
(17) The hall where it was held is only a stone’s throw from Jaywick , the jumble of former holiday chalets and potholed streets that is reckoned to be the poorest council ward in England: on the face of it, a symbol of the kind of deep social problems that tend to be synonymous with political apathy.
(18) We even have an app to report potholes in the city, which in one month registered more than 2,000.
(19) If you can show the council was aware of a dangerous pothole, and yet several weeks later you drove into it and damaged your car, you have a claim.
(20) All very idealistic except for the potholes, lorries and dust!
Slough
Definition:
(a.) Slow.
(n.) A place of deep mud or mire; a hole full of mire.
(n.) A wet place; a swale; a side channel or inlet from a river.
() imp. of Slee, to slay. Slew.
(n.) The skin, commonly the cast-off skin, of a serpent or of some similar animal.
(n.) The dead mass separating from a foul sore; the dead part which separates from the living tissue in mortification.
(v. i.) To form a slough; to separate in the form of dead matter from the living tissues; -- often used with off, or away; as, a sloughing ulcer; the dead tissues slough off slowly.
(v. t.) To cast off; to discard as refuse.
Example Sentences:
(1) Mucosal sloughing with hemorrhage and infarction were observed at 3 hours.
(2) More suppliers have told the Guardian of extensive negotiations with Amazon staff in Slough, adding to the impression that the company carries out important trading activities in the UK and so could be liable for tax.
(3) In mammalian small intestine absorptive cells are known to migrate from the villus base to the villus tip from which they slough.
(4) The most marked effect of the ZnSO4 took the form of necrosis and sloughing of surface cells in both strains one-half day after ZnSO4 irrigation.
(5) Cameron’s call for the Malaysian political class to fight corruption came as he pitched the country’s financiers the chance to invest in £17bn worth of UK infrastructure projects ranging from a Leeds orbital road route, Slough town centre and prime residential properties along the Thames.
(6) The histopathologic features include peritubular sclerosis, small vessel sclerosis, premature germ cell sloughing, and variable degrees of hypospermatogenesis.
(7) Changes in sperm head morphology are caused by (1) a dramatic reshaping and consolidation of the acrosome in which excess plasma membrane overlying it is sloughed as a cluster of vesicles, (2) a reorientation of the nucleus almost parallel to the axis of the tail and (3) distal movement of the droplet from its initial envelopment of the nucleus to an eccentric position on the anterior segment of the midpiece.
(8) Acute hypothermia induced a sloughing of cells from the villi into the lumen of the gut, as indicated by an increased DNA in luminal washings.
(9) Toxic epidermal necrolysis results in skin sloughing that resembles a partial-thickness thermal injury.
(10) Scanning electron microscopy revealed that in diabetic BB rats there was consistent evidence of swollen cells, raised nuclei, and sloughing of nuclei in endothelial cells of the aorta.
(11) However, after sloughing of labelled cells in the intestinal lumen, Pu was reabsorbed by the distal epithelial cells.
(12) It places the implant deep to prevent skin slough and irregularities in skin surface contour.
(13) Newer communities have settled in towns and cities such as Milton Keynes, Slough, Northampton, Southampton, and in London, notably Ealing, Tower Hamlets and Newham.
(14) Sloughing vesiculobullous oral lesions are a frequent component.
(15) Within 1 day of injury, columnar epithelium sloughed intact from the trachea with a concomitant reduction of nearly 35% in the basal cell population.
(16) Early changes (0-2 hours) included focal tumor and endothelial cell vacuolation and swelling as well as sloughing of tumor cells into papillary spaces.
(17) Histologically, the 4.0 ppm animals demonstrated bronchiolar epithelial necrosis and sloughing, bronchiolar edema with macrophages, and focal pulmonary edema.
(18) Ciliated cells had a slightly vesiculated cytoplasm, and many were in the process of being sloughed from the epithelial surface.
(19) Preliminary histochemical studies show that terminin is also found in the superficial epithelial layer of the esophagus, where terminal differentiation is followed by apoptosis and sloughing off into the lumen.
(20) In both the mouse and the rat, some of the superficial cells sloughed between fetal day 18 or 19 and the day of birth.